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List of works by David A Keire

31P nuclear magnetic resonance spectra and dissociation constants of lac repressor headpiece.duplex operator complexes: the importance of phosphate backbone flexibility in protein.DNA recognition

scientific article published on 01 July 1993

A Cautionary Tale: Quantitative LC-HRMS Analytical Procedures for the Analysis of N-Nitrosodimethylamine in Metformin

scientific article published on 01 July 2020

A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36)

scientific article published on 08 April 2008

Analyses of marketplace tacrolimus drug product quality: bioactivity, NMR and LC-MS.

scientific article published on 12 July 2013

Analysis of crude heparin by (1)H NMR, capillary electrophoresis, and strong-anion-exchange-HPLC for contamination by over sulfated chondroitin sulfate.

scientific article published on 30 October 2009

Analytical techniques and bioactivity assays to compare the structure and function of filgrastim (granulocyte-colony stimulating factor) therapeutics from different manufacturers.

scientific article

Assay of possible economically motivated additives or native impurities levels in heparin by 1H NMR, SAX-HPLC, and anticoagulation time approaches.

scientific article published on 20 February 2010

Characterization of currently marketed heparin products: analysis of molecular weight and heparinase-I digest patterns.

scientific article

Characterization of currently marketed heparin products: key tests for LMWH quality assurance.

scientific article published on 16 July 2013

Characterization of currently marketed heparin products: key tests for quality assurance

scientific article

Characterization of currently marketed heparin products: reversed-phase ion-pairing liquid chromatography mass spectrometry of heparin digests.

scientific article

Chelators for radioimmunotherapy: I. NMR and ab initio calculation studies on 1,4,7,10-tetra(carboxyethyl)-1,4,7,10-tetraazacyclododecane (DO4Pr) and 1,4,7-tris(carboxymethyl)-10-(carboxyethyl)-1,4,7,10-tetraazacyclododecane (DO3A1Pr).

scientific article published in August 2001

Chemoenzymatic synthesis and structural characterization of 2-O-sulfated glucuronic acid-containing heparan sulfate hexasaccharides

scientific article

Combining (1)H NMR spectroscopy and chemometrics to identify heparin samples that may possess dermatan sulfate (DS) impurities or oversulfated chondroitin sulfate (OSCS) contaminants.

scientific article published on 16 December 2010

Combining NMR Spectroscopy and Chemometrics to Monitor Structural Features of Crude Hep-arin

scientific article published on 08 July 2017

Crucial role of position 40 for interactions of CCK-58 revealed by sequence of cat CCK-58

scientific article published on 28 July 2006

Detection of possible economically motivated adulterants in heparin sodium and low molecular weight heparins with a colorimetric microplate based assay

scientific article published on 22 August 2011

Determination of galactosamine impurities in heparin samples by multivariate regression analysis of their (1)H NMR spectra.

scientific article published on 16 October 2010

Differences in receptor binding and stability to enzymatic digestion between CCK-8 and CCK-58.

scientific article published in October 2002

Differential bile-pancreatic secretory effects of CCK-58 and CCK-8 ⬇️

scientific article published on November 6, 2003

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

scientific article published on 22 December 2018

Ghost-Pill-Buster: A Case Study of Intact Levetiracetam Extended-Release Tablets after Dissolution Testing

scientific article published on 01 May 2016

High-throughput differentiation of heparin from other glycosaminoglycans by pyrolysis mass spectrometry

scientific article published on 24 July 2013

Identical primary sequence but different conformations of the bioactive regions of canine CCK-8 and CCK-58.

scientific article published on December 1999

Identification of heparin samples that contain impurities or contaminants by chemometric pattern recognition analysis of proton NMR spectral data.

scientific article

Minor N-Glycan Mapping of Monoclonal Antibody Therapeutics Using Middle-Down NMR Spectroscopy

scientific article published on 11 December 2020

Modern analytics for naturally derived complex drug substances: NMR and MS tests for protamine sulfate from chum salmon

scientific article published on 27 September 2014

Modern analytics for synthetically derived complex drug substances: NMR, AFFF-MALS, and MS tests for glatiramer acetate

scientific article

NMR evidence for different conformations of the bioactive region of rat CCK-8 and CCK-58

scientific article published on 01 May 2002

NMR profiling of biomolecules at natural abundance using 2D 1H-15N and 1H-13C multiplicity-separated (MS) HSQC spectra

scientific article

NMR studies of the metal-loading kinetics and acid-base chemistry of DOTA and butylamide-DOTA.

scientific article published on May 1999

PYY(1-36) is the major form of PYY in rat distal small intestine: quantification using high-resolution mass spectrometry

scientific article published on 06 July 2010

Rat progastrin processing yields peptides with altered potency at the CCK-B receptor.

scientific article published in May 2003

Sensitive detection of oversulfated chondroitin sulfate in heparin sodium or crude heparin with a colorimetric microplate based assay

scientific article published on 30 March 2011

Sequence variation outside the "active" region of dog and rabbit cholecystokinin-58 results in bioactivity differences.

scientific article

Simple NMR methods for evaluating higher order structures of monoclonal antibody therapeutics with quinary structure.

scientific article published on 7 June 2016

Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry.

scientific article published in May 2013

Structure and receptor binding of PYY analogs.

scientific article

Synthesis and detection of N-sulfonated oversulfated chondroitin sulfate in marketplace heparin

scientific article published on 13 August 2015

Synthesis of biologically active canine CCK-58.

scientific article published in May 2003

The US regulatory and pharmacopeia response to the global heparin contamination crisis.

scientific article published in June 2016

The conformation of substance P in lipid environments.

scientific article published on April 1996

The impact of standard accelerated stability conditions on antibody higher order structure as assessed by mass spectrometry

scientific article published on 15 April 2019

The interaction of beta-amyloid protein fragment (12-28) with lipid environments.

scientific article published on March 1997

The lipid-associated 3D structure of SPA, a broad-spectrum neuropeptide antagonist with anticancer properties.

scientific article

The micelle-associated 3D structures of Boc-Y(SO3)-Nle-G-W-Nle-D-2-phenylethylester (JMV-180) and CCK-8(s) share conformational elements of a calculated CCK1 receptor-bound model.

scientific article published on 10 June 2008

[Anaphylactoid reactions associated with contaminated heparin from China]

scientific article published on 02 August 2011

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