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List of works by Trevor Dale

3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors

scientific article published on 18 August 2020

A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators.

scientific article published on 8 December 2015

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.

scientific article

A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes

scientific article published in Nature

Alterations of the growth characteristics of the fibroblast cell line C3H 10T1/2 by members of the Wnt gene family.

scientific article published on September 1994

Amyloid-associated nucleic acid hybridisation.

scientific article

An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts

scientific article published on 01 November 1998

Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases

scientific article (publication date: 9 December 2016)

Comparison of methods for generating planar DNA-modified surfaces for hybridization studies.

scientific article

Compartment switching of WNT-2 expression in human breast tumors

scientific article published on 01 October 1996

Conditional disruption of Axin1 leads to development of liver tumors in mice

scientific article published on 6 September 2012

Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice

scientific article published on 7 July 2005

Developmental and hormonal regulation of Wnt gene expression in the mouse mammary gland

scientific article published in September 1994

Developmentally regulated splice variants mediate transcriptional repressor functions during eye formation

scientific article published on 12 December 2019

Discovery of potent, orally bioavailable, small-molecule inhibitors of WNT signaling from a cell-based pathway screen.

scientific article published on 13 February 2015

Dishevelled (Dvl-2) activates canonical Wnt signalling in the absence of cytoplasmic puncta.

scientific article published in November 2005

Doing More with Less: A Method for Low Total Mass, Affinity Measurement Using Variable-Length Nanotethers ⬇️

scientific article published on November 8, 2011

Erratum to: Functional and molecular characterisation of mammary side population cells

scientific article

Evolutionary routes from a prebiotic ANA-world ⬇️

scientific article published on March 1, 2012

Expression patterns of the novel receptor-like tyrosine kinase, DDR, in human breast tumours

scientific article published on 01 February 1995

Glycogen synthase kinase 3: a key regulator of cellular fate.

scientific article

H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC

scientific article

HGF/SF: a potent cytokine for mammary growth, morphogenesis and development

scientific article

High-level expression of the rat whey acidic protein gene is mediated by elements in the promoter and 3' untranslated region ⬇️

scientific article published on March 1, 1992

Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway

scientific article published on 18 March 2014

Identification of the Axin and Frat binding region of glycogen synthase kinase-3.

scientific article

In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system ⬇️

scientific article published on April 2, 2012

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

scientific article published on May 1999

Investigating h-Prune activation of Wnt signalling in breast cancer.

scientific article published on 13 May 2008

Kinase cogs go forward and reverse in the Wnt signaling machine

scientific article published in January 2006

Protein and nucleic acid together: a mechanism for the emergence of biological selection

scientific article published on 14 November 2005

Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins

scientific article

Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development

scientific journal article

Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium.

scientific article published in June 2000

Signal transduction by the Wnt family of ligands ⬇️

scientific article published on January 15, 1998

Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening.

scientific article published on 4 August 2016

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

scientific article

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

scientific article

The potential for targeting oncogenic WNT/beta-catenin signaling in therapy.

scientific article

The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP.

scientific article published on 9 September 2002

The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt ⬇️

scientific article

Toward a quantitative understanding of the Wnt/β-catenin pathway through simulation and experiment

scientific article published on 29 March 2013

Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C. elegans

scientific article

WNT-3A regulates an Axin1/NRF2 complex that regulates antioxidant metabolism in hepatocytes.

scientific article

Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids

scientific article published on 26 October 2016

Wnt signal transduction: kinase cogs in a nano-machine?

scientific article published in July 2002

Wnt signalling in murine postnatal mammary gland development.

scientific article published on 22 April 2011

Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

scientific article published on 12 September 2016

Wnt-4 expression induces a pregnancy-like growth pattern in reconstituted mammary glands in virgin mice

scientific article published in August 1995

Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development

scientific journal article

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