List of works - Mitchell Smith

A multicenter phase II trial to determine the safety and efficacy of combination therapy with denileukin diftitox and cyclophosphamide, doxorubicin, vincristine and prednisone in untreated peripheral T-cell lymphoma: the CONCEPT study.

scientific article

A phase 1 dose-escalation study of XmAb® 2513 in patients with relapsed or refractory Hodgkin lymphoma

scientific article published on 01 October 2014

A unique EBV-negative low-grade lymphoma line (WSU-FSCCL) exhibiting both t(14;18) and t(8;11).

scientific article published on October 1993

Aberrant Huntingtin interacting protein 1 in lymphoid malignancies

scientific article published on 01 September 2007

Allogeneic transplantation for lymphoma: risk-benefit balance is in the eye of the beholder

scientific article published on 14 May 2014

Altered levels of prothymosin immunoreactive peptide, a growth-related gene product, during liver regeneration after chronic ethanol feeding

scientific article published on 01 June 1994

An open-label phase 2 trial of entospletinib in indolent non-Hodgkin lymphoma and mantle cell lymphoma

scientific article published on 05 September 2018

Antibodies and hematologic malignancies.

scientific article published on May 2008

Antisense oligonucleotides complementary to immunoglobulin sequences of BCL-2/immunoglobulin fusion transcript induce apoptosis of t(14;18) lymphoma cells

scientific article published in December 2000

Bortezomib sensitizes non-Hodgkin's lymphoma cells to apoptosis induced by antibodies to tumor necrosis factor related apoptosis-inducing ligand (TRAIL) receptors TRAIL-R1 and TRAIL-R2.

scientific article

Brentuximab vedotin activity in diffuse large B-cell lymphoma with CD30 undetectable by visual assessment of conventional immunohistochemistry

scientific article

Brentuximab vedotin in anaplastic large cell lymphoma ⬇️

scientific article published on March 27, 2012

Clinical approach to diffuse large B cell lymphoma

scientific article

Clonal evolution of chronic lymphocytic leukemia to acute lymphoblastic leukemia

scientific article published on 01 February 1996

Coexisting myelodysplasia and myeloproliferative features in a single clone containing 5q-, Ph and i(17q)

scientific article published on 01 October 1999

Combination of ibrutinib with ABT-199: synergistic effects on proliferation inhibition and apoptosis in mantle cell lymphoma cells through perturbation of BTK, AKT and BCL2 pathways.

scientific article published on 4 October 2014

Comment on "Phase II study of weekly low-dose paclitaxel for relapsed and refractory non-Hodgkin's lymphoma: a Wisconsin Oncology Network Study," by Kahl et al., Cancer Investigation, 2005, 23(1), pp. 13-18

scientific article published on 01 January 2005

Contribution of flow cytometry in the diagnosis of cutaneous lymphoid lesions

scientific article published in December 2003

Cutaneous B-cell lymphoma responds to rituximab: a report of five cases and a review of the literature.

scientific article published on September 2006

Cutaneous precursor B-cell lymphoblastic lymphoma in 2 adult patients: clinicopathologic and molecular cytogenetic studies with a review of the literature.

scientific article published on September 2008

Dexamethasone plus retinoids decrease IL-6/IL-6 receptor and induce apoptosis in myeloma cells

scientific article published on 01 September 1998

Dose dependent effects on cell cycle checkpoints and DNA repair by bendamustine

scientific article

Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice.

scientific article published on 13 June 2018

Emergence of myeloid stem cell line from T-lymphoid blastic phase of chronic myeloid leukemia in culture ⬇️

scientific article published on January 1, 1992

Extranodal NK/T-cell lymphoma nasal type: efficacy of pegaspargase. Report of two patients from the United Sates and review of literature.

scientific article

Frontline bortezomib and rituximab for the treatment of newly diagnosed high tumour burden indolent non-Hodgkin lymphoma: a multicentre phase II study

scientific article published on 25 April 2014

Gastric mucosa-associated lymphoid tissue lymphoma

scientific article published on 01 June 2010

Ibrutinib: a force with a dark side?

scientific article

Identification of Ezrin-Radixin-Moesin proteins as novel regulators of pathogenic B-cell receptor signaling and tumor growth in diffuse large B-cell lymphoma.

scientific article

Immunotherapy of cancer

scientific article published on 20 October 2009

Is early hematopoietic stem-cell transplantation necessary in mantle-cell lymphoma?

scientific article published on 16 December 2013

Lacrimal gland lymphoma: Role of radiation therapy

scientific article published in January 2012

Long-term outcomes, secondary malignancies and stem cell collection following bendamustine in patients with previously treated non-Hodgkin lymphoma.

scientific article published on 17 April 2017

Low NK cell counts in peripheral blood are associated with inferior overall survival in patients with follicular lymphoma.

scientific article published on 07 August 2013

MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies

scientific article

Management of mantle cell lymphoma in the elderly.

scientific article published on 12 May 2012

Mechanisms of polyanion stimulation of nuclear DNA synthesis. Examination of thermal destabilization

scientific article published on 01 November 1977

Milatuzumab and veltuzumab induce apoptosis through JNK signalling in an NF-κB dependent human transformed follicular lymphoma cell line

scientific article

Molecular subtype classification of formalin-fixed, paraffin-embedded diffuse large B-cell lymphoma samples on the ICEPlex® system

scientific article

Murine mantle cell lymphoma model cell line ⬇️

scientific article published on December 28, 2012

Murine model for mantle cell lymphoma

scientific article published on 01 May 2006

Noninvasive phosphorus magnetic resonance spectroscopic imaging predicts outcome to first-line chemotherapy in newly diagnosed patients with diffuse large B-cell lymphoma

scientific article published on September 2013

Nucleosome arrangement in α-satellite chromatin of African green monkey cells ⬇️

scientific article published on August 24, 1984

Optimal use of novel agents in chronic lymphocytic leukemia

scientific article published on 07 May 2018

Parametric model of combination therapy for Non-Hodgkin Lymphoma

scientific article

Pediatric nodal marginal zone lymphoma may develop in the adult population.

scientific article published on January 2010

Phase 1/2 study of ocaratuzumab, an Fc-engineered humanized anti-CD20 monoclonal antibody, in low-affinity FcγRIIIa patients with previously treated follicular lymphoma.

scientific article published on 14 July 2014

Phase I study of bryostatin 1 and fludarabine in patients with chronic lymphocytic leukemia and indolent (non-Hodgkin's) lymphoma.

scientific article published on October 2006

Phase II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in combination with rituximab in patients with recurrent B-cell non-Hodgkin lymphoma

scientific article published on 01 September 2008

Phase II study of paclitaxel and estramustine in patients with recurrent and refractory non-Hodgkin lymphoma

scientific article

Phase II trial of idiotype vaccination in previously treated patients with indolent non-Hodgkin's lymphoma resulting in durable clinical responses

scientific article published on 05 June 2006

Prediction and Early Detection of Response by NMR Spectroscopy and Imaging

scientific article

Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905.

scientific article published on 24 March 2014

Prothymosin alpha: in search of a function.

scientific article published on July 1995

Quantitative electrophoretic transfer of DNA from polyacrylamide or agarose gels to nitrocellulose

scientific article published on 01 February 1984

Radioimmunotherapy in mantle cell lymphoma.

scientific article published on 09 May 2012

Results of a phase 1 study of AME-133v (LY2469298), an Fc-engineered humanized monoclonal anti-CD20 antibody, in FcγRIIIa-genotyped patients with previously treated follicular lymphoma

scientific article published on 05 January 2012

Role of ubiquitin carboxyl terminal hydrolase in the differentiation of human acute lymphoblastic leukemia cell line, Reh.

scientific article published on March 1996

Safety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab

scientific article

Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma: results of a phase I study

scientific article

Should there be a standard therapy for mantle cell lymphoma?

scientific article

Splenic marginal zone lymphoma: excellent outcomes in 64 patients treated in the rituximab era.

scientific article published on 20 January 2017

Stat3 Inhibition Augments the Immunogenicity of B-cell Lymphoma Cells, Leading to Effective Antitumor Immunity ⬇️

scientific article published on June 22, 2012

Targeting mTORC1-mediated metabolic addiction overcomes fludarabine resistance in malignant B cells.

scientific article

Tetanus Toxoid Reactive Lymphadenopathy Masquerading as T-Cell Lymphoma ⬇️

scientific article published on May 1, 2012

Treatment-related myelodysplastic syndrome following abdominopelvic radiotherapy for endometrial cancer

scientific article published on 01 June 1995

Urea reduces the thermal stability of polyanion-treated chromatin

scientific article published on February 21, 1977

Utilization of fine-needle aspiration cytology and flow cytometry in the diagnosis and subclassification of primary and recurrent lymphoma

scientific article published on 01 August 1998

List of works by Mitchell Smith

A multicenter phase II trial to determine the safety and efficacy of combination therapy with denileukin diftitox and cyclophosphamide, doxorubicin, vincristine and prednisone in untreated peripheral T-cell lymphoma: the CONCEPT study.

A phase 1 dose-escalation study of XmAb® 2513 in patients with relapsed or refractory Hodgkin lymphoma

A unique EBV-negative low-grade lymphoma line (WSU-FSCCL) exhibiting both t(14;18) and t(8;11).

Aberrant Huntingtin interacting protein 1 in lymphoid malignancies

Allogeneic transplantation for lymphoma: risk-benefit balance is in the eye of the beholder

Altered levels of prothymosin immunoreactive peptide, a growth-related gene product, during liver regeneration after chronic ethanol feeding

An open-label phase 2 trial of entospletinib in indolent non-Hodgkin lymphoma and mantle cell lymphoma

Antibodies and hematologic malignancies.

Antisense oligonucleotides complementary to immunoglobulin sequences of BCL-2/immunoglobulin fusion transcript induce apoptosis of t(14;18) lymphoma cells

Bortezomib sensitizes non-Hodgkin's lymphoma cells to apoptosis induced by antibodies to tumor necrosis factor related apoptosis-inducing ligand (TRAIL) receptors TRAIL-R1 and TRAIL-R2.

Brentuximab vedotin activity in diffuse large B-cell lymphoma with CD30 undetectable by visual assessment of conventional immunohistochemistry

Brentuximab vedotin in anaplastic large cell lymphoma ⬇️

Clinical approach to diffuse large B cell lymphoma

Clonal evolution of chronic lymphocytic leukemia to acute lymphoblastic leukemia

Coexisting myelodysplasia and myeloproliferative features in a single clone containing 5q-, Ph and i(17q)

Combination of ibrutinib with ABT-199: synergistic effects on proliferation inhibition and apoptosis in mantle cell lymphoma cells through perturbation of BTK, AKT and BCL2 pathways.

Comment on "Phase II study of weekly low-dose paclitaxel for relapsed and refractory non-Hodgkin's lymphoma: a Wisconsin Oncology Network Study," by Kahl et al., Cancer Investigation, 2005, 23(1), pp. 13-18

Contribution of flow cytometry in the diagnosis of cutaneous lymphoid lesions

Cutaneous B-cell lymphoma responds to rituximab: a report of five cases and a review of the literature.

Cutaneous precursor B-cell lymphoblastic lymphoma in 2 adult patients: clinicopathologic and molecular cytogenetic studies with a review of the literature.

Dexamethasone plus retinoids decrease IL-6/IL-6 receptor and induce apoptosis in myeloma cells

Dose dependent effects on cell cycle checkpoints and DNA repair by bendamustine

Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice.

Emergence of myeloid stem cell line from T-lymphoid blastic phase of chronic myeloid leukemia in culture ⬇️

Extranodal NK/T-cell lymphoma nasal type: efficacy of pegaspargase. Report of two patients from the United Sates and review of literature.

Frontline bortezomib and rituximab for the treatment of newly diagnosed high tumour burden indolent non-Hodgkin lymphoma: a multicentre phase II study

Gastric mucosa-associated lymphoid tissue lymphoma

Ibrutinib: a force with a dark side?

Identification of Ezrin-Radixin-Moesin proteins as novel regulators of pathogenic B-cell receptor signaling and tumor growth in diffuse large B-cell lymphoma.

Immunotherapy of cancer

Is early hematopoietic stem-cell transplantation necessary in mantle-cell lymphoma?

Lacrimal gland lymphoma: Role of radiation therapy

Long-term outcomes, secondary malignancies and stem cell collection following bendamustine in patients with previously treated non-Hodgkin lymphoma.

Low NK cell counts in peripheral blood are associated with inferior overall survival in patients with follicular lymphoma.

MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies

Management of mantle cell lymphoma in the elderly.

Mechanisms of polyanion stimulation of nuclear DNA synthesis. Examination of thermal destabilization

Milatuzumab and veltuzumab induce apoptosis through JNK signalling in an NF-κB dependent human transformed follicular lymphoma cell line

Molecular subtype classification of formalin-fixed, paraffin-embedded diffuse large B-cell lymphoma samples on the ICEPlex® system

Murine mantle cell lymphoma model cell line ⬇️

Murine model for mantle cell lymphoma

Noninvasive phosphorus magnetic resonance spectroscopic imaging predicts outcome to first-line chemotherapy in newly diagnosed patients with diffuse large B-cell lymphoma

Nucleosome arrangement in α-satellite chromatin of African green monkey cells ⬇️

Optimal use of novel agents in chronic lymphocytic leukemia

Parametric model of combination therapy for Non-Hodgkin Lymphoma

Pediatric nodal marginal zone lymphoma may develop in the adult population.

Phase 1/2 study of ocaratuzumab, an Fc-engineered humanized anti-CD20 monoclonal antibody, in low-affinity FcγRIIIa patients with previously treated follicular lymphoma.

Phase I study of bryostatin 1 and fludarabine in patients with chronic lymphocytic leukemia and indolent (non-Hodgkin's) lymphoma.

Phase II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in combination with rituximab in patients with recurrent B-cell non-Hodgkin lymphoma

Phase II study of paclitaxel and estramustine in patients with recurrent and refractory non-Hodgkin lymphoma

Phase II trial of idiotype vaccination in previously treated patients with indolent non-Hodgkin's lymphoma resulting in durable clinical responses

Prediction and Early Detection of Response by NMR Spectroscopy and Imaging

Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905.

Prothymosin alpha: in search of a function.

Quantitative electrophoretic transfer of DNA from polyacrylamide or agarose gels to nitrocellulose

Radioimmunotherapy in mantle cell lymphoma.

Results of a phase 1 study of AME-133v (LY2469298), an Fc-engineered humanized monoclonal anti-CD20 antibody, in FcγRIIIa-genotyped patients with previously treated follicular lymphoma

Role of ubiquitin carboxyl terminal hydrolase in the differentiation of human acute lymphoblastic leukemia cell line, Reh.

Safety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab

Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma: results of a phase I study

Should there be a standard therapy for mantle cell lymphoma?

Splenic marginal zone lymphoma: excellent outcomes in 64 patients treated in the rituximab era.

Stat3 Inhibition Augments the Immunogenicity of B-cell Lymphoma Cells, Leading to Effective Antitumor Immunity ⬇️

Targeting mTORC1-mediated metabolic addiction overcomes fludarabine resistance in malignant B cells.

Tetanus Toxoid Reactive Lymphadenopathy Masquerading as T-Cell Lymphoma ⬇️

Treatment-related myelodysplastic syndrome following abdominopelvic radiotherapy for endometrial cancer

Urea reduces the thermal stability of polyanion-treated chromatin

Utilization of fine-needle aspiration cytology and flow cytometry in the diagnosis and subclassification of primary and recurrent lymphoma