List of works - Aude Bonehill

A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients ⬇️

scientific article published on July 31, 2013

Activation of monocytes via the CD14 receptor leads to the enhanced lentiviral transduction of immature dendritic cells

scientific article published in June 2004

Characterization of CD8+ T-cell responses in the peripheral blood and skin injection sites of melanoma patients treated with mRNA electroporated autologous dendritic cells (TriMixDC-MEL)

scientific article published on 3 January 2013

Dendritic Cells Loaded With mRNA Encoding Full-length Tumor Antigens Prime CD4+ and CD8+ T Cells in Melanoma Patients ⬇️

scientific article published on February 28, 2012

Design of an Optimized Wilms' Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo

scientific article

Engineering Dendritic Cells to Enhance Cancer Immunotherapy ⬇️

scientific article published on 05 April 2011

Epitope and HLA-type independent monitoring of antigen-specific T-cells after treatment with dendritic cells presenting full-length tumor antigens

scientific article published on 16 January 2012

Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells

scientific article

Functional T-cell responses generated by dendritic cells expressing the early HIV-1 proteins Tat, Rev and Nef.

scientific article

Hemorrhagic regression of melanoma metastases during therapeutic vaccination: a report of three cases

scientific article published in December 2009

Induction of antigen-specific CD8+ cytotoxic T cells by dendritic cells co-electroporated with a dsRNA analogue and tumor antigen mRNA.

scientific article published on 2 March 2006

Inefficient exogenous loading of a tapasin-dependent peptide onto HLA-B*44:02 can be improved by acid treatment or fixation of target cells

scientific article published on June 2012

Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient

scientific article published on 10 December 2011

Lumenal part of the DC-LAMP protein is not required for induction of antigen-specific T cell responses by means of antigen-DC-LAMP messenger RNA-electroporated dendritic cells.

scientific article published in April 2010

Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70.

scientific article published on 10 July 2013

Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula

scientific article

Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy

scientific article published on 15 February 2012

Restoration of tumor equilibrium after immunotherapy for advanced melanoma: three illustrative cases

scientific article published on 01 April 2011

Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.

scientific article published on 5 May 2009

List of works by Aude Bonehill

A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients ⬇️

Activation of monocytes via the CD14 receptor leads to the enhanced lentiviral transduction of immature dendritic cells

Characterization of CD8+ T-cell responses in the peripheral blood and skin injection sites of melanoma patients treated with mRNA electroporated autologous dendritic cells (TriMixDC-MEL)

Dendritic Cells Loaded With mRNA Encoding Full-length Tumor Antigens Prime CD4+ and CD8+ T Cells in Melanoma Patients ⬇️

Design of an Optimized Wilms' Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo

Engineering Dendritic Cells to Enhance Cancer Immunotherapy ⬇️

Epitope and HLA-type independent monitoring of antigen-specific T-cells after treatment with dendritic cells presenting full-length tumor antigens

Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells

Functional T-cell responses generated by dendritic cells expressing the early HIV-1 proteins Tat, Rev and Nef.

Hemorrhagic regression of melanoma metastases during therapeutic vaccination: a report of three cases

Induction of antigen-specific CD8+ cytotoxic T cells by dendritic cells co-electroporated with a dsRNA analogue and tumor antigen mRNA.

Inefficient exogenous loading of a tapasin-dependent peptide onto HLA-B*44:02 can be improved by acid treatment or fixation of target cells

Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient

Lumenal part of the DC-LAMP protein is not required for induction of antigen-specific T cell responses by means of antigen-DC-LAMP messenger RNA-electroporated dendritic cells.

Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70.

Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula

Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy

Restoration of tumor equilibrium after immunotherapy for advanced melanoma: three illustrative cases

Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.