List of works - Allan Basbaum

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

scholarly article

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain ⬇️

scientific article published on November 16, 2011

A neuropeptide courier for delta-opioid receptors?

scientific article published in August 2005

A new way to lose your nerve

scientific article published on 14 April 2004

A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1.

scientific article published on 25 December 2013

Ablation of spinal cord estrogen receptor α-expressing interneurons reduces chemically induced modalities of pain and itch

scientific article published on 24 December 2019

Anatomical and functional analysis of aquaporin 1, a water channel in primary afferent neurons

scientific journal article

Behavioral indices of ongoing pain are largely unchanged in male mice with tissue or nerve injury-induced mechanical hypersensitivity

scientific article

Brain Responses to Noxious Stimuli in Patients With Chronic Pain: A Systematic Review and Meta-analysis

scientific article published on 04 January 2021

CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine

scientific article

Cell transplants to treat the "disease" of neuropathic pain and itch

scientific article

Cellular and Molecular Mechanisms of Pain

scientific article (publication date: October 2009)

Change is coming!

scientific article published on 18 December 2008

Characterization of Wide Dynamic Range Neurons in the Deep Dorsal Horn of the Spinal Cord in Preprotachykinin-A Null Mice In Vivo

scientific article published on 07 January 2004

Chemogenetic management of neuropathic pain.

scientific article published in October 2017

Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat.

scientific article published in April 2004

Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences

scholarly article

Contribution of substance P and neurokinin A to the differential injury-induced thermal and mechanical responsiveness of lamina I and V neurons

scientific article published on 01 January 2007

Contribution of the Reelin signaling pathways to nociceptive processing

scientific article

Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis

scientific article published on 15 January 2020

Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system

scientific article (publication date: 9 September 2005)

Decoy peptides that bind dynorphin noncovalently prevent NMDA receptor-mediated neurotoxicity

scientific article

Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn

scientific article published on 19 March 2014

Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn

scientific article

Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli

scientific article published on August 2010

Dissociation of the opioid receptor mechanisms that control mechanical and heat pain

scientific article

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

scholarly article

Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury.

scientific article published on 29 October 2015

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

scientific article published on 14 January 2020

Effect of topical 0.5% morphine on postoperative pain after photorefractive keratectomy

scientific article

Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations

scientific article

Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch

scientific article published on April 2013

Forebrain GABAergic neuron precursors integrate into adult spinal cord and reduce injury-induced neuropathic pain

scientific article published on May 2012

Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits.

scientific article

Functional Synaptic Integration of Forebrain GABAergic Precursors into the Adult Spinal Cord

scientific article

GABAergic cell transplants in the anterior cingulate cortex reduce neuropathic pain aversiveness

scientific article published on 01 September 2019

Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits

scientific article published on April 2008

Hippocalcin-like 4, a neural calcium sensor, has a limited contribution to pain and itch processing

scientific article published on 03 February 2020

Identification of multisegmental nociceptive afferents that modulate locomotor circuits in the neonatal mouse spinal cord.

scientific article published in August 2013

Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat.

scientific article published in March 2004

In Memoriam Jean-Marie Besson 1938-2014.

scientific article

Injured sensory neuron-derived CSF1 induces microglial proliferation and DAP12-dependent pain.

scientific article published on 7 December 2015

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

scientific article

Innocuous, not noxious, input activates PKCgamma interneurons of the spinal dorsal horn via myelinated afferent fibers

scientific article published on August 2008

Inputs to serotonergic neurons revealed by conditional viral transneuronal tracing

scientific article published on May 2009

Interneurons from embryonic development to cell-based therapy

scientific article

Introducing the Biennial review of pain

scientific article published on 07 December 2010

Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo

scientific article

Long-term deprivation of substance P in PPT-A mutant mice alters the anoxic response of the isolated respiratory network

scientific article published in July 2002

Long-term, dynamic synaptic reorganization after GABAergic precursor cell transplantation into adult mouse spinal cord

scientific article published on 13 November 2017

Loss of function genetic screens reveal MTGR1 as an intracellular repressor of beta1 integrin-dependent neurite outgrowth

scientific article

Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release

scientific article published on 6 March 2017

Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli

scientific article

Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion

scientific article published on 25 April 2019

Mispositioned Neurokinin-1 Receptor-Expressing Neurons Underlie Heat Hyperalgesia in Disabled-1 Mutant Mice.

scientific article published in May 2019

Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn

scientific article published on 01 February 2019

Mu and delta opioid receptor-like immunoreactivity in the cervical spinal cord of the rat after dorsal rhizotomy or neonatal capsaicin: an analysis of pre- and postsynaptic receptor distributions

scientific article published in March 2002

NaV1.1 inhibition can reduce visceral hypersensitivity

scientific article published on 07 June 2018

Neuronal aromatase expression in pain processing regions of the medullary and spinal cord dorsal horn

scientific article published on 26 June 2017

Olfactory ensheathing glia express aquaporin 1.

scientific article

Pain behavior in the formalin test persists after ablation of the great majority of C-fiber nociceptors

scientific article

Pain relief by supraspinal gabapentin requires descending noradrenergic inhibitory controls.

scientific article published on 17 July 2018

Paradoxical surrogate markers of dental injury-induced pain in the mouse

scientific article published on 11 April 2013

Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor

scientific article

Peptidergic nociceptors of both trigeminal and dorsal root ganglia express serotonin 1D receptors: implications for the selective antimigraine action of triptans.

scientific article

Peripheral and central neuronal ATF3 precedes CD4+ T-cell infiltration in EAE.

scientific article

Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T.

scientific article

Preprotachykinin-A gene deletion protects mice against acute pancreatitis and associated lung injury.

scientific article published in May 2003

Presynaptic Inputs to Any CNS Projection Neuron Identified by Dual Recombinant Virus Infection

scientific article published on 15 October 2015

Primary Afferent-Derived BDNF Contributes Minimally to the Processing of Pain and Itch

scientific article published on 01 November 2018

Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns

scientific article

Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan

scientific article published on 23 August 2008

Rebuilding CNS inhibitory circuits to control chronic neuropathic pain and itch

scientific article published on 2 January 2017

Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation

scientific article published in June 2002

Restriction of Transient Receptor Potential Vanilloid-1 to the Peptidergic Subset of Primary Afferent Neurons Follows Its Developmental Downregulation in Nonpeptidergic Neurons ⬇️

scientific article published on July 13, 2011

Reviews: topical, systematic and once again, comprehensive

scientific article published on 23 August 2006

Sciatic nerve transection triggers release and intercellular transfer of a genetically expressed macromolecular tracer in dorsal root ganglia ⬇️

scientific article published on September 1, 2011

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain

scientific journal article

Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis ⬇️

scientific article published on October 1, 2003

Spider toxins activate the capsaicin receptor to produce inflammatory pain.

scientific article

Spinal cord projection neurons: a superficial, and also deep, analysis

scientific article published on 10 October 2019

Sustaining intrinsic growth capacity of adult neurons promotes spinal cord regeneration

scientific article

Synergistic antipruritic effects of gamma aminobutyric acid A and B agonists in a mouse model of atopic dermatitis

scientific article published on 20 February 2017

Systemic morphine-induced release of serotonin in the rostroventral medulla is not mimicked by morphine microinjection into the periaqueductal gray

scientific article published in September 2003

TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing

scientific journal article

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

scientific journal article

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

scientific article

Targeting Pain Where It Resides … In the Brain ⬇️

scientific article published on January 12, 2011

The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. ⬇️

scientific article published in February 2002

The menthol receptor TRPM8 is the principal detector of environmental cold

scientific journal article

The modality-specific contribution of peptidergic and non-peptidergic nociceptors is manifest at the level of dorsal horn nociresponsive neurons

scientific article

Tissue injury regulates serotonin 1D receptor expression: implications for the control of migraine and inflammatory pain

scientific article

Toward better pain control.

scientific article

Transgenic Mouse Models for the Tracing of “Pain” Pathways ⬇️

scientific article published on September 2, 2011

Transition to chronic pain: opportunities for novel therapeutics

scientific article published on 01 July 2018

Transmitting pain and itch messages: a contemporary view of the spinal cord circuits that generate gate control.

scientific article published on May 2014

Transneuronal tracing of diverse CNS circuits by Cre-mediated induction of wheat germ agglutinin in transgenic mice

scientific article

Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch

scientific article published on 8 July 2014

Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity

scientific article published on June 2015

TrkB signaling is required for both the induction and maintenance of tissue and nerve injury-induced persistent pain

scientific article published on April 2009

Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells

scientific article

VGLUT2 expression in primary afferent neurons is essential for normal acute pain and injury-induced heat hypersensitivity.

scientific article

Where do triptans act in the treatment of migraine?

scientific article published on May 2005

List of works by Allan Basbaum

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain ⬇️

A neuropeptide courier for delta-opioid receptors?

A new way to lose your nerve

A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1.

Ablation of spinal cord estrogen receptor α-expressing interneurons reduces chemically induced modalities of pain and itch

Anatomical and functional analysis of aquaporin 1, a water channel in primary afferent neurons

Behavioral indices of ongoing pain are largely unchanged in male mice with tissue or nerve injury-induced mechanical hypersensitivity

Brain Responses to Noxious Stimuli in Patients With Chronic Pain: A Systematic Review and Meta-analysis

CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine

Cell transplants to treat the "disease" of neuropathic pain and itch

Cellular and Molecular Mechanisms of Pain

Change is coming!

Characterization of Wide Dynamic Range Neurons in the Deep Dorsal Horn of the Spinal Cord in Preprotachykinin-A Null Mice In Vivo

Chemogenetic management of neuropathic pain.

Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat.

Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences

Contribution of substance P and neurokinin A to the differential injury-induced thermal and mechanical responsiveness of lamina I and V neurons

Contribution of the Reelin signaling pathways to nociceptive processing

Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis

Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system

Decoy peptides that bind dynorphin noncovalently prevent NMDA receptor-mediated neurotoxicity

Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn

Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn

Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli

Dissociation of the opioid receptor mechanisms that control mechanical and heat pain

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury.

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

Effect of topical 0.5% morphine on postoperative pain after photorefractive keratectomy

Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations

Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch

Forebrain GABAergic neuron precursors integrate into adult spinal cord and reduce injury-induced neuropathic pain

Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits.

Functional Synaptic Integration of Forebrain GABAergic Precursors into the Adult Spinal Cord

GABAergic cell transplants in the anterior cingulate cortex reduce neuropathic pain aversiveness

Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits

Hippocalcin-like 4, a neural calcium sensor, has a limited contribution to pain and itch processing

Identification of multisegmental nociceptive afferents that modulate locomotor circuits in the neonatal mouse spinal cord.

Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat.

In Memoriam Jean-Marie Besson 1938-2014.

Injured sensory neuron-derived CSF1 induces microglial proliferation and DAP12-dependent pain.

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

Innocuous, not noxious, input activates PKCgamma interneurons of the spinal dorsal horn via myelinated afferent fibers

Inputs to serotonergic neurons revealed by conditional viral transneuronal tracing

Interneurons from embryonic development to cell-based therapy

Introducing the Biennial review of pain

Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo

Long-term deprivation of substance P in PPT-A mutant mice alters the anoxic response of the isolated respiratory network

Long-term, dynamic synaptic reorganization after GABAergic precursor cell transplantation into adult mouse spinal cord

Loss of function genetic screens reveal MTGR1 as an intracellular repressor of beta1 integrin-dependent neurite outgrowth

Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release

Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli

Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion

Mispositioned Neurokinin-1 Receptor-Expressing Neurons Underlie Heat Hyperalgesia in Disabled-1 Mutant Mice.

Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn

Mu and delta opioid receptor-like immunoreactivity in the cervical spinal cord of the rat after dorsal rhizotomy or neonatal capsaicin: an analysis of pre- and postsynaptic receptor distributions

NaV1.1 inhibition can reduce visceral hypersensitivity

Neuronal aromatase expression in pain processing regions of the medullary and spinal cord dorsal horn

Olfactory ensheathing glia express aquaporin 1.

Pain behavior in the formalin test persists after ablation of the great majority of C-fiber nociceptors

Pain relief by supraspinal gabapentin requires descending noradrenergic inhibitory controls.

Paradoxical surrogate markers of dental injury-induced pain in the mouse

Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor

Peptidergic nociceptors of both trigeminal and dorsal root ganglia express serotonin 1D receptors: implications for the selective antimigraine action of triptans.

Peripheral and central neuronal ATF3 precedes CD4+ T-cell infiltration in EAE.

Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T.

Preprotachykinin-A gene deletion protects mice against acute pancreatitis and associated lung injury.

Presynaptic Inputs to Any CNS Projection Neuron Identified by Dual Recombinant Virus Infection

Primary Afferent-Derived BDNF Contributes Minimally to the Processing of Pain and Itch

Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns

Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan

Rebuilding CNS inhibitory circuits to control chronic neuropathic pain and itch

Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation

Restriction of Transient Receptor Potential Vanilloid-1 to the Peptidergic Subset of Primary Afferent Neurons Follows Its Developmental Downregulation in Nonpeptidergic Neurons ⬇️

Reviews: topical, systematic and once again, comprehensive

Sciatic nerve transection triggers release and intercellular transfer of a genetically expressed macromolecular tracer in dorsal root ganglia ⬇️

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain

Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis ⬇️