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List of works by David Allsop

A demonstration of the advantages of immunostaining in the quantification of amyloid plaque deposits

scientific article published in January 1989

A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson's disease.

scientific article published on January 2013

A monoclonal antibody to common acute lymphoblastic leukemia antigen (neutral endopeptidase) immunostains senile plaques in the brains of patients with Alzheimer's disease ⬇️

scientific article published on January 2, 1991

A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease

scientific article

A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on beta-amyloid and alpha-synuclein

scientific article published in July 2006

Aggregation and metal-binding properties of mutant forms of the amyloid A beta peptide of Alzheimer's disease.

scientific article published in February 1996

Aggregation of Alzheimer's peptides

scientific article published on 01 February 1994

Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome.

scientific article published on July 1999

Amyloid deposition as the central event in the aetiology of Alzheimer's disease ⬇️

scientific article (publication date: October 1991)

Amyloid β-peptide and Alzheimer's disease.

scientific article published on January 2014

Amyloidosis in Alzheimer's disease.

scientific article

An investigation into the lipid-binding properties of alpha-, beta- and gamma-synucleins in human brain and cerebrospinal fluid

scientific article published on 20 July 2007

An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells

scientific article published on 01 February 1994

Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis

scientific article published on 15 October 2019

Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease

scientific article

Blood-based near-infrared spectroscopy for the rapid low-cost detection of Alzheimer's disease

scientific article published on 01 December 2018

CNS amyloid proteins in neurodegenerative diseases

scientific article published in October 1988

Cerebral amyloid angiopathy as a cause of subarachnoid hemorrhage.

scientific article

Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein.

scientific article published in October 1988

Combined use of CSF NfL and CSF TDP-43 improves diagnostic performance in ALS

scientific article published on 19 November 2019

Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126

scientific article published on 01 January 2003

Copper-mediated formation of hydrogen peroxide from the amylin peptide: A novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?

article

Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples ⬇️

scientific article published on June 27, 2013

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease

scientific article published on 14 August 2006

Designed Glycopeptidomimetics Disrupt Protein-Protein Interactions Mediating Amyloid β-Peptide Aggregation and Restore Neuroblastoma Cell Viability.

scientific article published on 20 January 2016

Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide.

scientific article published on 12 January 2008

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

scientific article published on 20 January 2009

Development & automation of a novel [(18)F]F prosthetic group, 2-[(18)F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide

scientific article published on 27 July 2016

Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

scientific article published on April 2010

Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes

scientific article published on 20 October 2017

Diagnostic Biomarkers for Alzheimer's Disease Using Non-Invasive Specimens

scientific article published on 01 June 2020

Differential diagnosis of Alzheimer's disease using spectrochemical analysis of blood.

scientific article published on 5 September 2017

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

scientific article

Donepezil for severe Alzheimer's disease

scientific article published in The Lancet

Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy.

scientific article

Effect of aluminium on expression and processing of amyloid precursor protein

scientific article published in November 1996

Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide.

scientific article published on 29 June 2011

Effects of different isoforms of apoE on aggregation of the α-synuclein protein implicated in Parkinson's disease

scientific article

Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid beta/A4 peptide

scientific article published in October 1993

Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme.

scientific article published on September 1993

Evidence for the derivation of a peptide ligand from the amyloid beta-protein precursor of Alzheimer's disease.

scientific article

Evidence of amyloid beta-protein immunoreactive early plaque lesions in Down's syndrome brains

article

Fe(II)‐induced DNA damage in α‐synuclein‐transfected human dopaminergic BE(2)‐M17 neuroblastoma cells: detection by the Comet assay ⬇️

scientific article published on November 1, 2003

Fibrillogenesis of beta-amyloid

scientific article published in August 1998

Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease

scientific article

Galantamine inhibits beta-amyloid aggregation and cytotoxicity

scientific article

Gelatinase A not alpha-secretase?

scientific article published in Nature

Gerstmann-Sträussler-Scheinker disease showing beta-protein type cerebellar and cerebral amyloid angiopathy

scientific article published on 01 January 1994

High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

scientific article

Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research.

scientific article published on November 1994

Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.

scientific article

Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

scientific article published on 07 November 2008

Increased levels of plasma total tau in adult Down syndrome.

scientific article published on 30 November 2017

Inflammatory mechanisms in Alzheimer's disease.

scientific article published on December 1994

Inherited frontotemporal dementia in nine British families associated with intronic mutations in the tau gene.

scientific article published on April 2002

Liposome delivery systems for the treatment of Alzheimer's disease

scholarly article by Callum Ross et al published 12 December 2018 in International Journal of Nanomedicine

Magnetite pollution nanoparticles in the human brain

scientific article published on 06 September 2016

Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease.

scientific article published on December 2008

Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

scientific article published in July 1986

Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. An immunohistochemical study using amyloid beta-protein antibody.

scientific article published in January 1989

New evidence that the Alzheimer beta-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps.

scientific article published in May 2001

Parkinson disease: Progress towards a molecular biomarker for Parkinson disease

scientific article published on 01 July 2010

Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease and related disorders

scientific article published on 01 March 2012

Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

scientific article published on 24 August 2011

Pick's disease is associated with mutations in the tau gene

scientific article published in December 2000

Plasma amyloid-β concentrations in Alzheimer's disease: an alternative hypothesis

scientific article published on 01 December 2006

Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

scientific article published on 05 April 2019

Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

scientific article

Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies.

scientific article published on 10 August 2011

Presenilins--in search of functionality

scientific article published in August 1998

Quantification of beta A4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type

scientific article published on August 3, 1992

Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease and down syndrome.

scientific article published on 4 September 2017

Quantitative differences in the deposition of beta A4 protein in the sulci and gyri of frontal and temporal isocortex in Alzheimer's disease

scientific article published in February 1992

Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

scientific article

Raman Spectroscopy to Diagnose Alzheimer's Disease and Dementia with Lewy Bodies in Blood

scientific article published on 14 June 2018

Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer's Aβ peptide

scientific article published on 18 October 2016

Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks beta/A4 amyloid immunoreactivity

scientific article published in March 1993

Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives.

scientific article published on 08 March 2017

TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype

scientific article

TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration

scientific article published on 28 May 2008

The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation

scientific article published on 2 June 2011

The immunoreactive profile at the N-terminal region of A beta 1-39/40 but not A beta 1-42 changes with transition from monomer/dimer to further peptide aggregates

scientific article published on 01 December 1995

The isolation and amino acid composition of senile plaque core protein

scientific article published in January 1983

Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation.

scientific article

Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aβ oligomers

scientific article published on 3 May 2012

Variability of beta-amyloid protein deposited lesions in Down's syndrome brains

scientific article published in November 1994

alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro

scientific article

α-Synuclein Interacts with Lipoproteins in Plasma.

scientific article published on 8 September 2017

β(A4)-amyloid protein and parkinsonian-dementia complex of Guam ⬇️

scientific article published on January 5, 1991

β-Hairpin mimics containing a piperidine-pyrrolidine scaffold modulate the β-amyloid aggregation process preserving the monomer species.

scientific article published on 7 October 2016

β-amyloid fibrils in Alzheimer disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species.

scientific article published on 11 March 2014

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