Search filters

List of works by Dirk M Zajonc

A 'GEM' of a cell

scientific article published in July 2013

A Novel Glycolipid Antigen for NKT Cells That Preferentially Induces IFN-γ Production

scientific article

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense

scientific article

A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides

scientific article published on 07 August 2019

A γδ T-cell glimpse of glycolipids

scientific article

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on 08 October 2009

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on December 2009

Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor

scientific article

Anatomy of CD1-lipid antigen complexes

scientific article

Antibody Recognition of Immunodominant Vaccinia Virus Envelope Proteins

scientific article published on January 2017

Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail

scientific article

Autoreactivity to Sulfatide by Human Invariant NKT Cells

scientific article published on 19 May 2017

CD1 assembly and the formation of CD1-antigen complexes

scientific article

CD1 mediated T cell recognition of glycolipids

scientific article published on 24 October 2007

CD1, MR1, NKT, and MAIT: evolution and origins of non-peptidic antigen recognition by T lymphocytes

scientific article published on August 2016

CD1c caves in on lipids

scientific article published on 01 April 2018

Carbohydrate specificity of the recognition of diverse glycolipids by natural killer T cells

scientific article published on July 2009

Cardiolipin Binds to CD1d and Stimulates CD1d-Restricted    T Cells in the Normal Murine Repertoire

scientific article

Catching a complex for optimal signaling

scientific article published on 01 September 2019

Characterization of murine antibody responses to vaccinia virus envelope protein A14 reveals an immunodominant antigen lacking of effective neutralization targets

scientific article published on 17 March 2018

Conservation of CD1 protein expression patterns in the chicken

scientific article

Crystal Structure of Bovine CD1b3 with Endogenously Bound Ligands

scientific article

Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A’ Pocket Unable to Bind Long-Chain Glycolipids

scientific article published in 2012

Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids

scientific article

Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A

scientific article

Crystal structure of Qa-1a with bound Qa-1 determinant modifier peptide

scientific article

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.

scientific article

Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding

scientific article published in Journal of Biological Chemistry

Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier

scientific article published in Journal of Biological Chemistry

Cutting Edge: Structural Basis for the Recognition of  -Linked Glycolipid Antigens by Invariant NKT Cells

scientific article

Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d

scholarly article

Divergent synthetic approach to 6''-modified α-GalCer analogues ⬇️

scientific article

Enhanced TCR Footprint by a Novel Glycolipid Increases NKT-Dependent Tumor Protection

scientific article

Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants

scientific article (publication date: April 2009)

Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

scientific article

Galactosylsphingamides: new α-GalCer analogues to probe the F'-pocket of CD1d

scientific article

Glycolipids that Elicit IFN-γ-Biased Responses from Natural Killer T Cells

scientific article

Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells

scientific article published on 02 December 2013

Histamine-releasing factor has a proinflammatory role in mouse models of asthma and allergy

scientific article published on December 2011

IEDB-3D: structural data within the immune epitope database

scientific article

ISC1-encoded inositol phosphosphingolipid phospholipase C is involved in Na+/Li+ halotolerance of Saccharomyces cerevisiae

scientific article

Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells ⬇️

scientific article published on February 21, 2012

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

scientific article

Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox

scientific article published on 17 February 2016

Lipid and Carbohydrate Modifications of α-Galactosylceramide Differently Influence Mouse and Human Type I Natural Killer T Cell Activation

scientific article published on 27 May 2015

Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

scientific article

Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V 14i NKT Cells

scientific article

Molecular basis of lipid antigen presentation by CD1d and recognition by natural killer T cells

scientific article

Molecular mechanism of lipopeptide presentation by CD1a

scientific article

Murine anti-vaccinia virus D8 antibodies target different epitopes and differ in their ability to block D8 binding to CS-E

scientific article

NKT cell ligand recognition logic: molecular basis for a synaptic duet and transmission of inflammatory effectors

scientific article published on August 2011

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria

scientific article published on 20 August 2006

Phage display generation of a novel human anti‐CD1A monoclonal antibody with potent cytolytic activity ⬇️

scientific article published on August 30, 2012

Polyclonal IgE induces mast cell survival and cytokine production

scientific article

Potent Neutralization of Vaccinia Virus by Divergent Murine Antibodies Targeting a Common Site of Vulnerability in L1 Protein

scientific article

Recognition of Microbial Glycolipids by Natural Killer T Cells

scientific article (publication date: 2015)

Recognition of lysophosphatidylcholine by type II NKT cells and protection from an inflammatory liver disease

scientific article

Role of lipid trimming and CD1 groove size in cellular antigen presentation

scientific article published on 22 June 2006

Structural Basis for Lipid-Antigen Recognition in Avian Immunity

scientific article

Structural Basis for the Recognition of C20:2-αGalCer by the Invariant Natural Killer T Cell Receptor-like Antibody L363

scientific article

Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5

scientific article

Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer

scientific article published on September 2015

Structural and Functional Characterization of a Novel Nonglycosidic Type I NKT Agonist with Immunomodulatory Properties

scientific article

Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity

scientific article

Structural basis of NKT cell inhibition using the T-cell receptor-blocking anti-CD1d antibody 1B1

scientific article published on 11 July 2019

Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d

scientific article published on October 2006

Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor

scientific article

Structure of an α-Helical Peptide and Lipopeptide Bound to the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule CD1d

scientific article published on 22 March 2016

Structure of human cytomegalovirus UL141 binding to TRAIL-R2 reveals novel, non-canonical death receptor interactions

scientific article

Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell lymphocyte attenuator

scientific article published on 24 May 2019

Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.

scientific article published on 9 November 2017

Synthesis and evaluation of amino-modified alpha-GalCer analogues

scientific article published on July 2010

Synthesis of C-5″ and C-6″-modified α-GalCer analogues as iNKT-cell agonists

scientific article

Synthesis of dideoxymycobactin antigens presented by CD1a reveals T cell fine specificity for natural lipopeptide structures

scientific article published on 15 July 2009

T cell activation by lipopeptide antigens

scientific article

T-cell activation by lipopeptide antigens

scientific article

The CD1 family: serving lipid antigens to T cells since the Mesozoic era.

scientific article

The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode

scientific article

The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid

scientific article published on 11 September 2012

The crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1

scientific article

The identification of the endogenous ligands of natural killer T cells reveals the presence of mammalian α-linked glycosylceramides

scientific article

The structure of cytomegalovirus immune modulator UL141 highlights structural Ig-fold versatility for receptor binding

scientific article

Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove

scientific article published on 29 January 2016

Two canine CD1a proteins are differentially expressed in skin

scientific article published on 17 May 2008

Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens

scientific article

Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.

scientific article

Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells

scientific article

Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine

scientific article published on 14 November 2012

Using a combined computational-experimental approach to predict antibody-specific B cell epitopes

scientific article published on 13 March 2014

pH-dependent interdomain tethers of CD1b regulate its antigen capture

scientific article published on June 2008

Paulina is supported by:

About Paulina

Help