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List of works by Helge Wiig

0729. Interstitial changes in spleen during sepsis.

scientific article

A 'new' mechanism for oedema generation: strongly negative interstitial fluid pressure causes rapid fluid flow into thermally injured skin

scientific article published on 01 March 1987

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

scientific article

A new method for isolation of interstitial fluid from human solid tumors applied to proteomic analysis of ovarian carcinoma tissue

scientific article

A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions.

scientific article published on 21 May 2008

Access to the spleen microenvironment through lymph shows local cytokine production, increased cell flux, and altered signaling of immune cells during lipopolysaccharide-induced acute inflammation

scientific article published on 17 March 2010

Acute kidney failure with renal carcinomatous lymphangitis secondary to advanced colon cancer.

scientific article published in August 2013

Acute peritoneal dialysis in rats results in a marked reduction of interstitial colloid osmotic pressure.

scientific article published in December 2004

Acute postburn edema: role of strongly negative interstitial fluid pressure

scientific article published on 01 November 1988

Adipose tissue macrophages: the inflammatory link between obesity and cancer?

scientific article

Age-related changes in rat dermal extracellular matrix composition affect the distribution of plasma proteins as a function of size and charge

scientific article published on 31 October 2014

Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume

scientific article

Blockade of Lymphangiogenesis Shapes Tumor-Promoting Adipose Tissue Inflammation

scientific article published on 29 July 2019

Blockade of beta 1-integrins in skin causes edema through lowering of interstitial fluid pressure

scientific article published in October 1992

Blood flow and interstitial fluid pressure in the rat submandibular gland during changes in perfusion

scientific article published in November 2003

Blood-tissue transport of exogenous albumin and immunoglobulin G in genetically analbuminemic rats

scientific article published on 01 February 1993

Colloid osmotic pressure of interstitial fluid in rat subcutis and skeletal muscle: comparison of various wick sampling techniques

scientific article published on 01 June 1988

Comparison of methods for measurement of interstitial fluid pressure in cat skin/subcutis and muscle

scientific article published in November 1985

Compliance of the interstitial space in rats. I. Studies on hindlimb skeletal muscle

scientific article published in January 1981

Compliance of the interstitial space in rats. II. Studies on skin

scientific article published in January 1981

Compliance of the interstitial space in rats. III. Contribution of skin and skeletal muscle interstitial fluid volume to changes in total extracellular fluid volume

scientific article published on 01 May 1984

Cornea fluid dynamics. I: measurement of hydrostatic and colloid osmotic pressure in rabbits

scientific article published in December 1989

Cytokine signalling in rat pulp interstitial fluid and transcapillary fluid exchange during lipopolysaccharide-induced acute inflammation

scientific article published on 09 March 2006

Cytokines are produced locally by myocytes in rat skeletal muscle during endotoxemia

scientific article published on 16 January 2009

Demonstration of altered signaling responses in bone marrow extracellular fluid during increased hematopoiesis in rats using a centrifugation method

scientific article published on 08 January 2004

Dendritic Cells Loaded with Tumor Antigens and a Dual Immunostimulatory and Anti-Interleukin 10-Specific Small Interference RNA Prime T Lymphocytes against Leukemic Cells.

scientific article published on December 2009

Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema

scientific article

Determination of lymph flow in murine oral mucosa using depot clearance of near-infrared-labeled albumin

scientific article published on 2 July 2015

Differential cytokine response in interstitial fluid in skin and serum during experimental inflammation in rats

scientific article published on 14 January 2004

Differential degradation of matrix proteoglycans and edema development in rabbit lung

scientific article published on 7 October 2005

Distribution of interstitial fluid pressure and fluid volumes in hind-limb skin of rats: relation to meridians?

scientific article

Distribution spaces for hyaluronan and albumin in rat tail tendons

scientific article

Distribution volumes of macromolecules in human ovarian and endometrial cancers--effects of extracellular matrix structure

scientific article published on 7 November 2014

Drainage of plasma proteins from the renal medullary interstitium in rats

scientific article published in October 2001

Effect of charge on interstitial distribution of albumin in rat dermis in vitro

scientific article published on 23 May 2003

Effect of hydration on interstitial distribution of charged albumin in rat dermis in vitro.

scientific article

Effect of topical anaesthetics on interstitial colloid osmotic pressure in human subcutaneous tissue sampled by wick technique

scientific article

Effects of hydration on steric and electric charge-induced interstitial volume exclusion--a model.

scientific article published on September 2013

Electrostatic, elastic and hydration-dependent interactions in dermis influencing volume exclusion and macromolecular transport

scientific article published on 11 April 2016

Fluid accumulation after closure of atrial septal defects: the role of colloid osmotic pressure

scientific article

Fluid accumulation in the staged Fontan procedure: the impact of colloid osmotic pressures

scientific article published on 01 April 2019

Fluid pressure in human dermal fibroblast aggregates measured with micropipettes

scientific article published on 23 July 2003

Fluid transport from the dental pulp revisited

scientific article published on 14 August 2020

GRHL2 Is Required for Collecting Duct Epithelial Barrier Function and Renal Osmoregulation

scientific article published on 13 December 2017

Gingival lymphatic drainage protects against Porphyromonas gingivalis-induced bone loss in mice

scientific article published on 01 September 2012

Hemodynamics and interstitial fluid pressure in the rat tail

scientific article published in July 1984

High dose vitamin C counteracts the negative interstitial fluid hydrostatic pressure and early edema generation in thermally injured rats.

scientific article

High-Salt Diet Causes Expansion of the Lymphatic Network and Increased Lymph Flow in Skin and Muscle of Rats

scientific article published on 01 September 2018

High-Salt Diet Causes Osmotic Gradients and Hyperosmolality in Skin Without Affecting Interstitial Fluid and Lymph.

scientific article

High-salt diet increases hormonal sensitivity in skin pre-capillary resistance vessels.

scientific article published on 10 January 2013

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

scientific article published on 03 June 2013

Impaired lymphatic function accelerates cancer growth

scientific article published on 13 June 2016

Importance of lymph vessels in the transcapillary fluid balance in the gingiva studied in a transgenic mouse model

scientific article published on 14 May 2010

In vivo determination of steric and electrostatic exclusion of albumin in rat skin and skeletal muscle

scientific article published on 22 August 2003

Increased WD-repeat containing protein 1 in interstitial fluid from ovarian carcinomas shown by comparative proteomic analysis of malignant and healthy gynecological tissue

scientific article published on 21 May 2013

Increased interstitial protein because of impaired lymph drainage does not induce fibrosis and inflammation in lymphedema

scientific article

Increased negativity of interstitial fluid pressure contributes to development of oedema in rat skin following application of xylene

scientific article published on 01 December 1990

Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumor model

scientific article published on August 2009

Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis.

scientific article published on 22 May 2012

Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma

scientific article published on December 2006

Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis

scientific article published on 08 November 2018

Interstitial IgG antibody pharmacokinetics assessed by combined in vivo- and physiologically-based pharmacokinetic modelling approaches.

scientific article published on 27 September 2017

Interstitial albumin mass and transcapillary extravasation rate of albumin in DMBA-induced rat mammary tumours

scientific article published on 01 October 1983

Interstitial compliance and transcapillary Starling pressures in cat skin and skeletal muscle

scientific article published on 01 May 1985

Interstitial compliance and transcapillary fluid balance in renal hypertensive rats

scientific article published on 01 July 1986

Interstitial exclusion of IgG in rat tissues estimated by continuous infusion

scientific article published in January 1994

Interstitial exclusion of albumin in rabbit lung during development of pulmonary oedema.

scientific article published on 21 March 2003

Interstitial exclusion of albumin in rabbit lung measured with the continuous infusion method in combination with the wick technique.

scientific article published in April 2003

Interstitial exclusion of albumin in rat dermis and subcutis in over- and dehydration

scientific article published on 01 December 1989

Interstitial exclusion of albumin in rat tissues measured by a continuous infusion method

scientific article published on October 1, 1992

Interstitial exclusion of macromolecules studied by graded centrifugation of rat tail tendon

scientific article published on 01 December 1997

Interstitial exclusion of positively and negatively charged IgG in rat skin and muscle.

scientific article published in April 2001

Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer

scientific article

Interstitial fluid colloid osmotic pressure in healthy children

scientific article

Interstitial fluid drainage from rat apical area takes place via vessels in the mandibular canal

scientific article published on 19 April 2020

Interstitial fluid pressure and hemodynamics in a sarcoma implanted in the rat tail

scientific article published on 01 March 1985

Interstitial fluid pressure in DMBA-induced rat mammary tumours

scientific article published on 01 April 1982

Interstitial fluid pressure in human skin measured by micropuncture and wick-in-needle

scientific article published on 01 May 1983

Interstitial fluid pressure surrounding rat mesenteric venules during changes in fluid filtration.

scientific article

Interstitial fluid pressure, composition of interstitium, and interstitial exclusion of albumin in hypothyroid rats

scientific article published on 01 May 2000

Interstitial fluid-a reflection of the tumor cell microenvironment and secretome.

scientific article published on 31 January 2013

Interstitial fluid: the overlooked component of the tumor microenvironment?

scientific article

Intraperitoneal immunotherapy for metastatic ovarian carcinoma: Resistance of intratumoral collagen to antibody penetration.

scientific article published on March 2006

Investigation of therapy resistance mechanisms in myeloid leukemia by protein profiling of bone marrow extracellular fluid ⬇️

scientific article published on December 1, 2012

Isolation of interstitial fluid and demonstration of local proinflammatory cytokine production and increased absorptive gradient in chronic peritoneal dialysis

scientific article published on 14 November 2012

Isolation of interstitial fluid from rat mammary tumors by a centrifugation method

scientific article published on 12 September 2002

Isolation of interstitial fluid from skeletal muscle and subcutis in mice using a wick method

scientific article

Isolation of interstitial fluid in skin during volume expansion: evaluation of a method in pigs.

scientific article published on 6 August 2010

Isolation of rat trachea interstitial fluid and demonstration of local cytokine production in lipopolysaccharide-induced systemic inflammation

scientific article published on 10 January 2008

Limits to steady-state lymph flow rates derived from plasma-to-tissue uptake measurements.

scientific article

Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4-dependent pathway and limits sensitivity to fluid therapy in mice

scientific article published on 16 December 2019

Loss of adipocyte specification and necrosis augment tumor-associated inflammation

scientific article published on 19 April 2013

Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion.

scientific article

Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model

scientific article

Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration

scientific article

Lymphangiogenesis and lymphatic function in periodontal disease.

scientific article published on 12 September 2013

Lymphatic function and responses in periodontal disease

scientific article published on 03 February 2014

Lymphatic vessels regulate immune microenvironments in human and murine melanoma

scientific article published on 15 August 2016

Measurement of colloid osmotic pressure in submicrolitre samples

scientific article published on 01 April 1988

Measurement of interstitial fluid pressure in dogs: evaluation of methods

scientific article published on 01 August 1987

Measurement of interstitial fluid pressure: comparison of methods

scientific article published on 01 January 1986

Mechanisms behind increased dermal imbibition pressure in acute burn edema

scientific article published on 01 April 1989

Micropuncture measurement of interstitial fluid pressure in rat subcutis and skeletal muscle: comparison to wick-in-needle technique

scientific article published on 01 May 1981

Microvascular pressures in DMBA-induced rat mammary tumours

scientific article published on 01 April 1982

Minimally invasive quantification of lymph flow in mice and rats by imaging depot clearance of near-infrared albumin

scientific article published on 18 November 2011

Modeling In Vivo Interstitial Hydration-Pressure Relationships in Skin and Skeletal Muscle

scientific article published on 04 August 2018

New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences.

scientific article

PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis

scientific article

Pathophysiology of tissue fluid accumulation in inflammation ⬇️

scientific article published on April 11, 2011

Peritumoral TNFalpha administration influences tumour stroma structure and physiology independently of growth in DMBA-induced mammary tumours

scientific article published in January 2008

Physiology and pathology of collagen receptors.

scientific article published on July 2007

Plasma protein charge: a major determinant of fluid exchange

scientific article published on 01 December 2008

Proteomic evaluation of inflammatory proteins in rat spleen interstitial fluid and lymph during LPS-induced systemic inflammation reveals increased levels of ADAMST1

Quantification of the concentration gradient of biomarkers between ovarian carcinoma interstitial fluid and blood.

scientific article

Rat brain interstitial fluid pressure measured with micropipettes

scientific article published on 01 February 1983

Regulation of Fluid Volume From the Outside: A Role of Glycosaminoglycans in the Skin Interstitium?

scientific article published on 01 July 2018

Relationship between interstitial fluid volume and pressure (compliance) in hypothyroid rats

scientific article published in September 2001

Role of Hyperplasia of Gingival Lymphatics in Periodontal Inflammation

scientific article published on December 2016

Sampling interstitial fluid from rat skeletal muscles by intermuscular wicks ⬇️

scientific article published on July 1, 1991

Simultaneous measurement of interstitial fluid pressure and load in rat skin after strain application in vitro

scientific article published in November 2003

Subcutaneous interstitial fluid colloid osmotic pressure in dehydrated rats

scientific article published on 01 July 1988

Subcutaneous interstitial pressure and volume characteristics in renal impairment associated with edema ⬇️

scientific article published on June 5, 2013

Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats

scientific article

The alpha11beta1 integrin has a mechanistic role in control of interstitial fluid pressure and edema formation in inflammation

scientific article published on 3 September 2009

The interstitial distribution of macromolecules in rat tumours is influenced by the negatively charged matrix components.

scientific article published on 30 June 2005

The interstitium conducts extrarenal storage of sodium and represents a third compartment essential for extracellular volume and blood pressure homeostasis

scientific article published on 28 November 2017

The notochord in Atlantic salmon (Salmo salar L.) undergoes profound morphological and mechanical changes during development

scientific article published on 8 August 2017

The problem of gaining access to interstitial fluid. An attempt to rationalize a wicked discussion on wicks

scientific article published on September 1997

The role of the extracellular matrix in tissue distribution of macromolecules in normal and pathological tissues: potential therapeutic consequences

scientific article published on May 2008

Transcapillary fluid balance consequences of missing initial lymphatics studied in a mouse model of primary lymphoedema

article

Transcapillary fluid flux and inflammatory response during neonatal therapeutic hypothermia: an open, longitudinal, observational study

scientific article published on 23 February 2018

Tumor Interstitial Fluid Formation, Characterization, and Clinical Implications

scientific article published on 26 May 2015

Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis

scientific article published on 01 October 2005

Unilateral renal ischaemia in rats induces a rapid secretion of inflammatory markers to renal lymph and increased capillary permeability.

scientific article published on 20 November 2015

Volume-pressure relationship (compliance) of interstitium in dog skin and muscle

scientific article published on 01 August 1987

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