List of works - Ulrike Kuckelkorn

20S proteasome-dependent generation of an IEpp89 murine cytomegalovirus-derived H-2L(d) epitope from a recombinant protein

scientific article published on 8 February 2007

Analysis of Proteasome Generated Antigenic Peptides by Mass Spectrometry ⬇️

scientific article published on January 1, 2013

Anti-20S proteasome autoantibodies inhibit proteasome stimulation by proteasome activator PA28

scientific article published on 01 July 2006

Anti-tumor activity of the proteasome inhibitor BSc2118 against human multiple myeloma

scientific article

Antigen-presentation capacity of dendritic cells is impaired in ongoing enterovirus myocarditis

scientific article published on 29 July 2011

Antitopes define preferential proteasomal cleavage site usage.

scientific article published on 18 April 2008

Assessment of proteasomal cleavage probabilities from kinetic analysis of time-dependent product formation

scientific article

BSc2118 is a novel proteasome inhibitor with activity against multiple myeloma

scientific article published on 31 March 2010

Biodistribution and Efficacy Studies of the Proteasome Inhibitor BSc2118 in a Mouse Melanoma Model

scientific article

Circulating proteasome levels are an independent prognostic factor for survival in multiple myeloma

scientific article

Circulating proteasomes are markers of cell damage and immunologic activity in autoimmune diseases

scientific article (publication date: October 2002)

Combined effect of proteasome and calpain inhibition on cisplatin-resistant human melanoma cells

scientific article published on August 2006

Curcumin diminishes human osteoclastogenesis by inhibition of the signalosome-associated I kappaB kinase

scientific article

Differential interferon responses enhance viral epitope generation by myocardial immunoproteasomes in murine enterovirus myocarditis

scientific article published on 9 July 2009

Elastase-like Activity Is Dominant to Chymotrypsin-like Activity in 20S Proteasome's β5 Catalytic Subunit

scientific article

Expression of proteasomal immunosubunit beta1i is dysregulated in inflammatory infiltrates of minor salivary glands in Sjogren's syndrome

scientific article published on 15 October 2009

Gene expression of catalytic proteasome subunits and resistance toward proteasome inhibition of B lymphocytes from patients with primary sjogren syndrome

scientific article published on 15 March 2013

Generation of in silico predicted coxsackievirus B3-derived MHC class I epitopes by proteasomes

scientific article published on 9 December 2009

Heme oxygenase-1 ameliorates ischemia/reperfusion injury by targeting dendritic cell maturation and migration

scientific article published on 01 December 2007

Humoral anti-proteasomal autoimmunity in dilated cardiomyopathy

scientific article published in January 2010

Immunoproteasomes are essential for clearance of Listeria monocytogenes in nonlymphoid tissues but not for induction of bacteria-specific CD8+ T cells

scientific article published on 01 November 2006

Immunoproteasomes are important for proteostasis in immune responses

scientific article published in February 2013

Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress

scientific article

Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis

scientific article

Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing

scientific article

LDL suppresses angiogenesis through disruption of the HIF pathway via NF-κB inhibition which is reversed by the proteasome inhibitor BSc2118.

scientific article published on 15 September 2015

Lack of evidence for a pathogenic role of proteasome-directed autoimmunity in dilated cardiomyopathy

scientific article published on 25 March 2010

Link between organ-specific antigen processing by 20S proteasomes and CD8(+) T cell-mediated autoimmunity

scientific article published on April 2002

Mapping of O-GlcNAc sites of 20 S proteasome subunits and Hsp90 by a novel biotin-cystamine tag ⬇️

scientific article published on May 3, 2012

Ongoing coxsackievirus myocarditis is associated with increased formation and activity of myocardial immunoproteasomes

scientific article

Pioglitazone, a PPAR-gamma ligand, exerts cytostatic/cytotoxic effects against cancer cells, that do not result from inhibition of proteasome.

scientific article

Prevalence of 20S proteasome, anti-nuclear and thyroid antibodies in young patients at onset of type 1 diabetes mellitus and the risk of autoimmune thyroiditis

scientific article

Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

scientific article published on 20 November 2014

Rapid degradation of solid-phase bound peptides by the 20S proteasome

scientific article published on 28 July 2013

Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma

scientific article published on 20 December 2007

Systemic Proteasome Inhibition Induces Sustained Post-stroke Neurological Recovery and Neuroprotection via Mechanisms Involving Reversal of Peripheral Immunosuppression and Preservation of Blood-Brain-Barrier Integrity

scientific article published on 16 November 2015

The N-terminal flanking region of the TRP2360-368 melanoma antigen determines proteasome activator PA28 requirement for epitope liberation

scientific article published on 16 February 2007

The effect of the interferon-gamma-inducible processing machinery on the generation of a naturally tumor-associated human cytotoxic T lymphocyte epitope within a wild-type and mutant p53 sequence context

scientific article

The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis

scientific article

The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35 -specific T-cell recognition

scientific article published on 24 September 2015

The proteasome system in infection: impact of β5 and LMP7 on composition, maturation and quantity of active proteasome complexes

scientific article

Tripeptide mimetics inhibit the 20 S proteasome by covalent bonding to the active threonines

scientific article published on 26 May 2005

Trypanosoma cruzi infection down-modulates the immunoproteasome biosynthesis and the MHC class I cell surface expression in HeLa cells

scientific article

α-Keto phenylamides as P1'-extended proteasome inhibitors

scientific article

List of works by Ulrike Kuckelkorn

20S proteasome-dependent generation of an IEpp89 murine cytomegalovirus-derived H-2L(d) epitope from a recombinant protein

Analysis of Proteasome Generated Antigenic Peptides by Mass Spectrometry ⬇️

Anti-20S proteasome autoantibodies inhibit proteasome stimulation by proteasome activator PA28

Anti-tumor activity of the proteasome inhibitor BSc2118 against human multiple myeloma

Antigen-presentation capacity of dendritic cells is impaired in ongoing enterovirus myocarditis

Antitopes define preferential proteasomal cleavage site usage.

Assessment of proteasomal cleavage probabilities from kinetic analysis of time-dependent product formation

BSc2118 is a novel proteasome inhibitor with activity against multiple myeloma

Biodistribution and Efficacy Studies of the Proteasome Inhibitor BSc2118 in a Mouse Melanoma Model

Circulating proteasome levels are an independent prognostic factor for survival in multiple myeloma

Circulating proteasomes are markers of cell damage and immunologic activity in autoimmune diseases

Combined effect of proteasome and calpain inhibition on cisplatin-resistant human melanoma cells

Curcumin diminishes human osteoclastogenesis by inhibition of the signalosome-associated I kappaB kinase

Differential interferon responses enhance viral epitope generation by myocardial immunoproteasomes in murine enterovirus myocarditis

Elastase-like Activity Is Dominant to Chymotrypsin-like Activity in 20S Proteasome's β5 Catalytic Subunit

Expression of proteasomal immunosubunit beta1i is dysregulated in inflammatory infiltrates of minor salivary glands in Sjogren's syndrome

Gene expression of catalytic proteasome subunits and resistance toward proteasome inhibition of B lymphocytes from patients with primary sjogren syndrome

Generation of in silico predicted coxsackievirus B3-derived MHC class I epitopes by proteasomes

Heme oxygenase-1 ameliorates ischemia/reperfusion injury by targeting dendritic cell maturation and migration

Humoral anti-proteasomal autoimmunity in dilated cardiomyopathy

Immunoproteasomes are essential for clearance of Listeria monocytogenes in nonlymphoid tissues but not for induction of bacteria-specific CD8+ T cells

Immunoproteasomes are important for proteostasis in immune responses

Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress

Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis

Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing

LDL suppresses angiogenesis through disruption of the HIF pathway via NF-κB inhibition which is reversed by the proteasome inhibitor BSc2118.

Lack of evidence for a pathogenic role of proteasome-directed autoimmunity in dilated cardiomyopathy

Link between organ-specific antigen processing by 20S proteasomes and CD8(+) T cell-mediated autoimmunity

Mapping of O-GlcNAc sites of 20 S proteasome subunits and Hsp90 by a novel biotin-cystamine tag ⬇️

Ongoing coxsackievirus myocarditis is associated with increased formation and activity of myocardial immunoproteasomes

Pioglitazone, a PPAR-gamma ligand, exerts cytostatic/cytotoxic effects against cancer cells, that do not result from inhibition of proteasome.

Prevalence of 20S proteasome, anti-nuclear and thyroid antibodies in young patients at onset of type 1 diabetes mellitus and the risk of autoimmune thyroiditis

Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

Rapid degradation of solid-phase bound peptides by the 20S proteasome

Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma

Systemic Proteasome Inhibition Induces Sustained Post-stroke Neurological Recovery and Neuroprotection via Mechanisms Involving Reversal of Peripheral Immunosuppression and Preservation of Blood-Brain-Barrier Integrity

The N-terminal flanking region of the TRP2360-368 melanoma antigen determines proteasome activator PA28 requirement for epitope liberation

The effect of the interferon-gamma-inducible processing machinery on the generation of a naturally tumor-associated human cytotoxic T lymphocyte epitope within a wild-type and mutant p53 sequence context

The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis

The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35 -specific T-cell recognition

The proteasome system in infection: impact of β5 and LMP7 on composition, maturation and quantity of active proteasome complexes

Tripeptide mimetics inhibit the 20 S proteasome by covalent bonding to the active threonines

Trypanosoma cruzi infection down-modulates the immunoproteasome biosynthesis and the MHC class I cell surface expression in HeLa cells

α-Keto phenylamides as P1'-extended proteasome inhibitors