List of works - Guanghong Wei

Adsorption and Orientation of Human Islet Amyloid Polypeptide (hIAPP) Monomer at Anionic Lipid Bilayers: Implications for Membrane-Mediated Aggregation

scientific article published on 19 March 2013

All-Atom Stability and Oligomerization Simulations of Polyglutamine Nanotubes with and without the 17-Amino-Acid N-Terminal Fragment of the Huntingtin Protein

Atomic-Level Study of Adsorption, Conformational Change, and Dimerization of an α-Helical Peptide at Graphene Surface

article by Luchun Ou et al published 18 August 2011 in Journal of Physical Chemistry

Atomistic Insights into A315E Mutation-Enhanced Pathogenicity of TDP-43 Core Fibrils

scientific article published in 2022

Atomistic-level study of the interactions between hIAPP protofibrils and membranes: Influence of pH and lipid composition.

scientific article published on 8 February 2018

Aβ(16-22) peptides can assemble into ordered β-barrels and bilayer β-sheets, while substitution of phenylalanine 19 by tryptophan increases the population of disordered aggregates

scientific article

Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning

scientific article published on 5 October 2017

Carbon nanotube inhibits the formation of β-sheet-rich oligomers of the Alzheimer's amyloid-β(16-22) peptide

scientific article published on November 2011

Common cancer mutations R175H and R273H drive the p53 DNA-binding domain towards aggregation-prone conformations

scientific article published on 20 April 2020

Complex folding pathways in a simple beta-hairpin

scientific article published in August 2004

Computational Investigation of Gantenerumab and Crenezumab's Recognition of Aβ Fibrils in Alzheimer's Disease Brain Tissue

scientific article published on 29 September 2020

Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau.

scientific article

Conformational distribution and α-helix to β-sheet transition of human amylin fragment dimer

scientific article published on 16 December 2013

Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization

scientific article published on 8 August 2016

Conformational stability and dynamics of the cancer-associated isoform Δ133p53β are modulated by p53 peptides and p53-specific DNA

scientific article published on 12 December 2018

Critical nucleus of Greek-key-like core of α-synuclein protofibril and its disruption by dopamine and norepinephrine

scientific article published on 01 December 2019

Cross-seeding and conformational selection between three- and four-repeat human Tau proteins

scientific article published on 5 March 2012

Deciphering the Rules for Amino Acid Co-Assembly Based on Interlayer Distances

scientific article published on 25 January 2019

Dihydrochalcone molecules destabilize Alzheimer's amyloid-β protofibrils through binding to the protofibril cavity

article published in 2018

Effect of impurity on ion neutralization

scientific article published on 01 September 1995

Effect of the disulfide bond on the monomeric structure of human amylin studied by combined Hamiltonian and temperature replica exchange molecular dynamics simulations

scientific article published in May 2010

Effects of G33A and G33I mutations on the structures of monomer and dimer of the amyloid-β fragment 29-42 by replica exchange molecular dynamics simulations

scientific article

Effects of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: a coarse-grained molecular dynamics study

scientific article published on 29 November 2011

Effects of solvent on the structure of the Alzheimer amyloid-beta(25-35) peptide

scientific article

Effects of the RGTFEGKF Inhibitor on the Structures of the Transmembrane Fragment 70−86 of Glycophorin A: An All-Atom Molecular Dynamics Study

Epigallocatechin Gallate Destabilizes α-Synuclein Fibril by Disrupting the E46-K80 Salt-Bridge and Inter-protofibril Interface

scientific article published on 13 November 2020

Expanding the structural diversity of peptide assemblies by coassembling dipeptides with diphenylalanine

scientific article published on 23 January 2020

Exploring the early steps of aggregation of amyloid-forming peptide KFFE

Exploring the energy landscape of proteins: A characterization of the activation-relaxation technique

Formation of α-helical and β-sheet structures in membrane-bound human IAPP monomer and the resulting membrane deformation

scientific article published on 01 September 2019

Gate-Controlled Sum-Frequency Vibrational Spectroscopy for Probing Charged Oxide/Water Interfaces

scientific article published on 20 September 2019

Hydrophobic interaction drives surface-assisted epitaxial assembly of amyloid-like peptides

scientific article

Induced beta-barrel formation of the Alzheimer's Abeta25-35 oligomers on carbon nanotube surfaces: implication for amyloid fibril inhibition

scientific article published in September 2009

Influence of fullerenol on hIAPP aggregation: amyloid inhibition and mechanistic aspects

scientific article published on 01 February 2019

Inhibitory effect of hydrophobic fullerenes on the β-sheet-rich oligomers of a hydrophilic GNNQQNY peptide revealed by atomistic simulations

scholarly article in RSC Advances, vol. 7 no. 23, 2017

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.

scientific article published on April 2016

Interactions of Aβ25-35 β-barrel-like oligomers with anionic lipid bilayer and resulting membrane leakage: an all-atom molecular dynamics study

scientific article

Investigation of the Dissociation Mechanism of Single-Walled Carbon Nanotube on Mature Amyloid-β Fibrils at Single Nanotube Level

scientific article published on 13 April 2020

Lattice dynamics of zinc-blende GaN and AlN: I. Bulk phonons

article

Lattice dynamics of zinc-blende GaN and AlN: II. Superlattice phonons

Lipid interaction and membrane perturbation of human islet amyloid polypeptide monomer and dimer by molecular dynamics simulations.

scientific article

Long-range-order effects on the ion neutralization process

scientific article published on 01 October 1995

Mechanistic insight into E22Q-mutation-induced antiparallel-to-parallel β-sheet transition of Aβ16-22 fibrils: an all-atom simulation study

scientific article published on 01 July 2019

Mechanistic insights into the inhibition and size effects of graphene oxide nanosheets on the aggregation of an amyloid-β peptide fragment

Membrane binding and insertion of a pHLIP peptide studied by all-atom molecular dynamics simulations

scientific article published on 12 July 2013

Molecular Dynamics Simulations Reveal the Inhibitory Mechanism of Dopamine against Human Islet Amyloid Polypeptide (hIAPP) Aggregation and Its Destabilization Effect on hIAPP Protofibrils

scientific article published on 03 September 2019

Molecular dynamics simulations reveal the mechanism of graphene oxide nanosheet inhibition of Aβ1-42 peptide aggregation

scientific article published on 21 May 2019

Molecular insights into the reversible formation of tau protein fibrils

scientific article published on May 2013

Norepinephrine Inhibits Alzheimer's Amyloid-β Peptide Aggregation and Destabilizes Amyloid-β Protofibrils: A Molecular Dynamics Simulation Study

scientific article published on 15 January 2019

Pathway complexity of Alzheimer's beta-amyloid Abeta16-22 peptide assembly

scientific article published in July 2004

Phase transition of nanotube-confined water driven by electric field

scientific article

Plugging into Proteins: Poisoning Protein Function by a Hydrophobic Nanoparticle

Probing ion channel activity of human islet amyloid polypeptide (amylin).

scientific article

Probing the Self-Assembly Mechanism of Diphenylalanine-Based Peptide Nanovesicles and Nanotubes

Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel–Lindau tumor suppressor protein

Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell

scientific article published on 25 January 2016

Replica Exchange Molecular Dynamics: A Practical Application Protocol with Solutions to Common Problems and a Peptide Aggregation and Self-Assembly Example

scientific article published on 01 January 2018

STRUCTURAL INSIGHT INTO THE POLYMORPHISM OF NNQNTF PROTOFIBRIL: IMPORTANCE OF INTERFACIAL WATER, POLAR AND AROMATIC RESIDUES

Sampling the complex energy landscape of a simple β-hairpin

article

Sampling the self-assembly pathways of KFFE hexamers

scientific article published on 17 September 2004

Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant.

scientific article published on 29 February 2016

Self-assembly of amyloid-forming peptides by molecular dynamics simulations

scientific article published on May 2008

Self-assembly of the beta2-microglobulin NHVTLSQ peptide using a coarse-grained protein model reveals a beta-barrel species

article

Sequence effects on peptide assembly characteristics observed by using scanning tunneling microscopy

scientific article

Single mutations in tau modulate the populations of fibril conformers through seed selection

scientific article

Structural Insight into Tau Protein's Paradox of Intrinsically Disordered Behavior, Self-Acetylation Activity, and Aggregation

scientific article

Structural Polymorphism in a Self-Assembled Tri-Aromatic Peptide System.

scientific article published on 20 March 2018

Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms

scientific article published in Journal of Biological Chemistry

Structural diversity of dimers of the Alzheimer amyloid-beta(25-35) peptide and polymorphism of the resulting fibrils

scientific article published on 11 March 2010

Structural diversity of the soluble trimers of the human amylin(20-29) peptide revealed by molecular dynamics simulations

scientific article

Structural, thermodynamical, and dynamical properties of oligomers formed by the amyloid NNQQ peptide: Insights from coarse-grained simulations

Structure and Thermodynamics of Amylin Dimer Studied by Hamiltonian-Temperature Replica Exchange Molecular Dynamics Simulations

article

Structure and aggregation mechanism of beta(2)-microglobulin (83-99) peptides studied by molecular dynamics simulations

scientific article

Study on Molecular Cavity of Oligoamide Macrocycles by Using Scanning Tunneling Microscopy

The Inhibitory Effect of Hydroxylated Carbon Nanotubes on the Aggregation of Human Islet Amyloid Polypeptide Revealed by a Combined Computational and Experimental Study

The beta-strand-loop-beta-strand conformation is marginally populated in beta2-microglobulin (20-41) peptide in solution as revealed by replica exchange molecular dynamics simulations

scientific article published on 11 April 2008

The distinct structural preferences of tau protein repeat domains

Thermodynamics and dynamics of amyloid peptide oligomerization are sequence dependent

article

List of works by Guanghong Wei

Adsorption and Orientation of Human Islet Amyloid Polypeptide (hIAPP) Monomer at Anionic Lipid Bilayers: Implications for Membrane-Mediated Aggregation

All-Atom Stability and Oligomerization Simulations of Polyglutamine Nanotubes with and without the 17-Amino-Acid N-Terminal Fragment of the Huntingtin Protein

Atomic-Level Study of Adsorption, Conformational Change, and Dimerization of an α-Helical Peptide at Graphene Surface

Atomistic Insights into A315E Mutation-Enhanced Pathogenicity of TDP-43 Core Fibrils

Atomistic-level study of the interactions between hIAPP protofibrils and membranes: Influence of pH and lipid composition.

Aβ(16-22) peptides can assemble into ordered β-barrels and bilayer β-sheets, while substitution of phenylalanine 19 by tryptophan increases the population of disordered aggregates

Binding of protofibrillar Aβ trimers to lipid bilayer surface enhances Aβ structural stability and causes membrane thinning

Carbon nanotube inhibits the formation of β-sheet-rich oligomers of the Alzheimer's amyloid-β(16-22) peptide

Common cancer mutations R175H and R273H drive the p53 DNA-binding domain towards aggregation-prone conformations

Complex folding pathways in a simple beta-hairpin

Computational Investigation of Gantenerumab and Crenezumab's Recognition of Aβ Fibrils in Alzheimer's Disease Brain Tissue

Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau.

Conformational distribution and α-helix to β-sheet transition of human amylin fragment dimer

Conformational dynamics of cancer-associated MyD88-TIR domain mutant L252P (L265P) allosterically tilts the landscape toward homo-dimerization

Conformational stability and dynamics of the cancer-associated isoform Δ133p53β are modulated by p53 peptides and p53-specific DNA

Critical nucleus of Greek-key-like core of α-synuclein protofibril and its disruption by dopamine and norepinephrine

Cross-seeding and conformational selection between three- and four-repeat human Tau proteins

Deciphering the Rules for Amino Acid Co-Assembly Based on Interlayer Distances

Dihydrochalcone molecules destabilize Alzheimer's amyloid-β protofibrils through binding to the protofibril cavity

Effect of impurity on ion neutralization

Effect of the disulfide bond on the monomeric structure of human amylin studied by combined Hamiltonian and temperature replica exchange molecular dynamics simulations

Effects of G33A and G33I mutations on the structures of monomer and dimer of the amyloid-β fragment 29-42 by replica exchange molecular dynamics simulations

Effects of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: a coarse-grained molecular dynamics study

Effects of solvent on the structure of the Alzheimer amyloid-beta(25-35) peptide

Effects of the RGTFEGKF Inhibitor on the Structures of the Transmembrane Fragment 70−86 of Glycophorin A: An All-Atom Molecular Dynamics Study

Epigallocatechin Gallate Destabilizes α-Synuclein Fibril by Disrupting the E46-K80 Salt-Bridge and Inter-protofibril Interface

Expanding the structural diversity of peptide assemblies by coassembling dipeptides with diphenylalanine

Exploring the early steps of aggregation of amyloid-forming peptide KFFE

Exploring the energy landscape of proteins: A characterization of the activation-relaxation technique

Formation of α-helical and β-sheet structures in membrane-bound human IAPP monomer and the resulting membrane deformation

Gate-Controlled Sum-Frequency Vibrational Spectroscopy for Probing Charged Oxide/Water Interfaces

Hydrophobic interaction drives surface-assisted epitaxial assembly of amyloid-like peptides

Induced beta-barrel formation of the Alzheimer's Abeta25-35 oligomers on carbon nanotube surfaces: implication for amyloid fibril inhibition

Influence of fullerenol on hIAPP aggregation: amyloid inhibition and mechanistic aspects

Inhibitory effect of hydrophobic fullerenes on the β-sheet-rich oligomers of a hydrophilic GNNQQNY peptide revealed by atomistic simulations

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.

Interactions of Aβ25-35 β-barrel-like oligomers with anionic lipid bilayer and resulting membrane leakage: an all-atom molecular dynamics study

Investigation of the Dissociation Mechanism of Single-Walled Carbon Nanotube on Mature Amyloid-β Fibrils at Single Nanotube Level

Lattice dynamics of zinc-blende GaN and AlN: I. Bulk phonons

Lattice dynamics of zinc-blende GaN and AlN: II. Superlattice phonons

Lipid interaction and membrane perturbation of human islet amyloid polypeptide monomer and dimer by molecular dynamics simulations.

Long-range-order effects on the ion neutralization process

Mechanistic insight into E22Q-mutation-induced antiparallel-to-parallel β-sheet transition of Aβ16-22 fibrils: an all-atom simulation study

Mechanistic insights into the inhibition and size effects of graphene oxide nanosheets on the aggregation of an amyloid-β peptide fragment

Membrane binding and insertion of a pHLIP peptide studied by all-atom molecular dynamics simulations

Molecular Dynamics Simulations Reveal the Inhibitory Mechanism of Dopamine against Human Islet Amyloid Polypeptide (hIAPP) Aggregation and Its Destabilization Effect on hIAPP Protofibrils

Molecular dynamics simulations reveal the mechanism of graphene oxide nanosheet inhibition of Aβ1-42 peptide aggregation

Molecular insights into the reversible formation of tau protein fibrils

Norepinephrine Inhibits Alzheimer's Amyloid-β Peptide Aggregation and Destabilizes Amyloid-β Protofibrils: A Molecular Dynamics Simulation Study

Pathway complexity of Alzheimer's beta-amyloid Abeta16-22 peptide assembly

Phase transition of nanotube-confined water driven by electric field

Plugging into Proteins: Poisoning Protein Function by a Hydrophobic Nanoparticle

Probing ion channel activity of human islet amyloid polypeptide (amylin).

Probing the Self-Assembly Mechanism of Diphenylalanine-Based Peptide Nanovesicles and Nanotubes

Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel–Lindau tumor suppressor protein

Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell

Replica Exchange Molecular Dynamics: A Practical Application Protocol with Solutions to Common Problems and a Peptide Aggregation and Self-Assembly Example

STRUCTURAL INSIGHT INTO THE POLYMORPHISM OF NNQNTF PROTOFIBRIL: IMPORTANCE OF INTERFACIAL WATER, POLAR AND AROMATIC RESIDUES

Sampling the complex energy landscape of a simple β-hairpin

Sampling the self-assembly pathways of KFFE hexamers

Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant.

Self-assembly of amyloid-forming peptides by molecular dynamics simulations

Self-assembly of the beta2-microglobulin NHVTLSQ peptide using a coarse-grained protein model reveals a beta-barrel species

Sequence effects on peptide assembly characteristics observed by using scanning tunneling microscopy

Single mutations in tau modulate the populations of fibril conformers through seed selection

Structural Insight into Tau Protein's Paradox of Intrinsically Disordered Behavior, Self-Acetylation Activity, and Aggregation

Structural Polymorphism in a Self-Assembled Tri-Aromatic Peptide System.

Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms

Structural diversity of dimers of the Alzheimer amyloid-beta(25-35) peptide and polymorphism of the resulting fibrils

Structural diversity of the soluble trimers of the human amylin(20-29) peptide revealed by molecular dynamics simulations

Structural, thermodynamical, and dynamical properties of oligomers formed by the amyloid NNQQ peptide: Insights from coarse-grained simulations

Structure and Thermodynamics of Amylin Dimer Studied by Hamiltonian-Temperature Replica Exchange Molecular Dynamics Simulations

Structure and aggregation mechanism of beta(2)-microglobulin (83-99) peptides studied by molecular dynamics simulations

Study on Molecular Cavity of Oligoamide Macrocycles by Using Scanning Tunneling Microscopy

The Inhibitory Effect of Hydroxylated Carbon Nanotubes on the Aggregation of Human Islet Amyloid Polypeptide Revealed by a Combined Computational and Experimental Study

The beta-strand-loop-beta-strand conformation is marginally populated in beta2-microglobulin (20-41) peptide in solution as revealed by replica exchange molecular dynamics simulations

The distinct structural preferences of tau protein repeat domains

Thermodynamics and dynamics of amyloid peptide oligomerization are sequence dependent