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List of works by Raul Torres-Ruiz

A chemokine targets the nucleus: Cxcl12-gamma isoform localizes to the nucleolus in adult mouse heart

scientific article

A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

scientific article published on 17 February 2022

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

scientific article published on 25 November 2021

An integration-defective lentivirus-based resource for site-specific targeting of an edited safe-harbour locus in the human genome.

scientific article published on 6 February 2014

CRISPR-Cas9 technology: applications and human disease modelling

scientific article published on 26 June 2016

CRISPR-Cas9: A Revolutionary Tool for Cancer Modelling

scientific article

CRISPR/Cas9 for Cancer Therapy: Hopes and Challenges

scientific article published on 12 November 2018

Clinically Relevant Correction of Recessive Dystrophic Epidermolysis Bullosa by Dual sgRNA CRISPR/Cas9-Mediated Gene Editing

scientific article published on 15 March 2019

Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9.

scientific article

Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system

scientific article published on 3 June 2014

Epigenetic reprogramming of primary pancreatic cancer cells counteracts their in vivo tumourigenicity

scientific article published on 15 July 2019

Gain-of-function mutations in DNMT3A in patients with paraganglioma

scientific article published on 08 May 2018

Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA

scientific article published on 16 October 2019

Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity.

scientific article

In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells

scientific article published on 08 October 2020

Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism

scientific article published on 25 November 2021

Narrowing the Genetic Causes of Language Dysfunction in the 1q21.1 Microduplication Syndrome.

scientific article published on 5 June 2018

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy

scientific article published in November 2011

Non-integrative lentivirus drives high-frequency cre-mediated cassette exchange in human cells

scientific article

Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

scientific article published on 13 April 2018

The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia

scientific article published on 20 June 2017

Truncated RUNX1 protein generated by a novel t(1;21)(p32;q22) chromosomal translocation impairs the proliferation and differentiation of human hematopoietic progenitors

scientific article

mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis

scientific article

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