Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines

Elephants, Mobility and Captivity: What Can These Mighty and Majestic Animals Teach Us About Joint Health and Osteoarthritis?

Elephants, Mobility and Captivity: What Can These Mighty and Majestic Animals Teach Us About Joint Health and Osteoarthritis?

Faculty Opinions recommendation of A biphasic multiscale study of the mechanical microenvironment of chondrocytes within articular cartilage under unconfined compression.

Faculty Opinions recommendation of A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats.

Faculty Opinions recommendation of A gene expression study of normal and damaged cartilage in anteromedial gonarthrosis, a phenotype of osteoarthritis.

Faculty Opinions recommendation of A new initiative on precision medicine.

Faculty Opinions recommendation of A single blunt impact on cartilage promotes fibronectin fragmentation and upregulates cartilage degrading stromelysin-1/matrix metalloproteinase-3 in a bovine ex vivo model.

Faculty Opinions recommendation of Advances in TRP channel drug discovery: from target validation to clinical studies.

Faculty Opinions recommendation of Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.

Faculty Opinions recommendation of Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism.

Faculty Opinions recommendation of Articular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis.

Faculty Opinions recommendation of Association between cartilage and bone biomarkers and incidence of radiographic knee osteoarthritis (RKOA) in UK females: a prospective study.

Faculty Opinions recommendation of Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization.

Faculty Opinions recommendation of Cell-based articular cartilage repair: the link between development and regeneration.

Faculty Opinions recommendation of Clinical settings in knee osteoarthritis: Pathophysiology guides treatment.

Faculty Opinions recommendation of Comparison of rheumatoid arthritis (RA) and osteoarthritis (OA) based on microarray profiles of human joint fibroblast-like synoviocytes.

Faculty Opinions recommendation of Concept endpoints informing design considerations for confirmatory clinical trials in osteoarthritis.

Faculty Opinions recommendation of Differentiation of adipose-derived stem cells into contractile smooth muscle cells induced by transforming growth factor-beta1 and bone morphogenetic protein-4.

Faculty Opinions recommendation of Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone.

Faculty Opinions recommendation of Effect of Magnetic Resonance Imaging vs Conventional Treat-to-Target Strategies on Disease Activity Remission and Radiographic Progression in Rheumatoid Arthritis: The IMAGINE-RA Randomized Clinical Trial.

Faculty Opinions recommendation of Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease.

Faculty Opinions recommendation of Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes.

Faculty Opinions recommendation of FK506 protects against articular cartilage collagenous extra-cellular matrix degradation.

Faculty Opinions recommendation of Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function.

Faculty Opinions recommendation of How to pick a graduate advisor.

Faculty Opinions recommendation of Identification of serological biomarker profiles associated with total joint replacement in osteoarthritis patients.

Faculty Opinions recommendation of In-vitro and in-vivo imaging of MMP activity in cartilage and joint injury.

Faculty Opinions recommendation of Inflammation induces irreversible biophysical changes in isolated nucleus pulposus cells.

Faculty Opinions recommendation of KCa1.1 inhibition attenuates fibroblast-like synoviocyte invasiveness and ameliorates disease in rat models of rheumatoid arthritis.

Faculty Opinions recommendation of Learning to be a mentor.

Faculty Opinions recommendation of Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment.

Faculty Opinions recommendation of MRI-based screening for structural definition of eligibility in clinical DMOAD trials: Rapid OsteoArthritis MRI Eligibility Score (ROAMES).

Faculty Opinions recommendation of Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin.

Faculty Opinions recommendation of Osteoarthritis.

Faculty Opinions recommendation of Osteoarthritis: In search of phenotypes.

Faculty Opinions recommendation of Patient evaluation and OA study design: oarsi/biomarker qualification.

Faculty Opinions recommendation of Quantification of "end products" of tissue destruction in inflammation may reflect convergence of cytokine and signaling pathways -- implications for modern clinical chemistry.

Faculty Opinions recommendation of Serological biomarker profiles of rapidly progressive osteoarthritis in tanezumab-treated patients.

Faculty Opinions recommendation of Synovial fluid biomarkers associated with osteoarthritis severity reflect macrophage and neutrophil related inflammation.

Faculty Opinions recommendation of TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading.

Faculty Opinions recommendation of The active form of MMP-3 is a marker of synovial inflammation and cartilage turnover in inflammatory joint diseases.

Faculty Opinions recommendation of The genetic program for cartilage development has deep homology within Bilateria.

Faculty Opinions recommendation of Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis.

Faculty Opinions recommendation of Use of biomarkers to identify phenotypes and endotypes of severe asthma.

Faculty Opinions recommendation of Where should I send it? Optimizing the submission decision process.

Faculty Opinions recommendation of Why training and specialization is needed for peer review: a case study of peer review for randomized controlled trials.

Osteoarthritis

Over-production of Therapeutic Growth Factors for Articular Cartilage Regeneration by Protein Production Platforms and Protein Packaging Cell Lines

Physiological Effects of the Electrogenic Current Generated by the Na /K Pump in Mammalian Articular Chondrocytes

The Antihypertensive Drug Nifedipine Modulates the Metabolism of Chondrocytes and Human Bone Marrow-Derived Mesenchymal Stem Cells