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List of works by Mehmet K Tur

An anti-GD2 single chain Fv selected by phage display and fused to Pseudomonas exotoxin A develops specific cytotoxic activity against neuroblastoma derived cell lines.

scientific article

An aptamer-siRNA chimera silences the eukaryotic elongation factor 2 gene and induces apoptosis in cancers expressing αvβ3 integrin.

scientific article published on April 2013

Antibody Selection on FFPE Tissue Slides

scientific article published in January 2018

CD30 as a therapeutic target for lymphoma

scientific article

Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2.

scientific article

Combined human papillomavirus typing and TP53 mutation analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma

scientific article published on 09 March 2018

Combining phage display and screening of cDNA expression libraries: a new approach for identifying the target antigen of an scFv preselected by phage display.

scientific article

Construction of phage display libraries from reactive lymph nodes of breast carcinoma patients and selection for specifically binding human single chain Fv on cell lines.

scientific article published in October 2004

Detection of an activated JAK3 variant and a Xq26.3 microdeletion causing loss of PHF6 and miR-424 expression in myelodysplastic syndromes by combined targeted next generation sequencing and SNP array analysis.

scientific article published on 23 February 2014

Development of a monoclonal sandwich ELISA for direct detection of bluetongue virus 8 in infected animals.

scientific article

Fcgamma receptor 1 (CD64), a target beyond cancer.

scientific article published on January 2009

Generation of recombinant antibody fragments that target canine dendritic cells by phage display technology.

scientific article

Granzyme B-H22(scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes.

scientific article published on September 2008

Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma ⬇️

scientific article published on December 15, 2001

Immunokinases, a novel class of immunotherapeutics for targeted cancer therapy.

scientific article published on January 2009

Improved immunotoxins with novel functional elements.

scientific article published on January 2009

In vitro effects and ex vivo binding of an EGFR-specific immunotoxin on rhabdomyosarcoma cells

scientific article

In vivo efficacy of the recombinant anti-CD64 immunotoxin H22(scFv)-ETA' in a human acute myeloid leukemia xenograft tumor model

scientific article published on 26 February 2011

Measurement of antibody-membrane interactions by surface plasmon resonance.

scientific article

Metalloproteinase inhibition augments antitumor efficacy of the anti-CD30 immunotoxin Ki-3(scFv)-ETA' against human lymphomas in vivo

scientific article published in September 2004

Molecular Targeting Therapy against EGFR Family in Breast Cancer: Progress and Future Potentials

scientific article published on 20 November 2019

Novel PSCA targeting scFv-fusion proteins for diagnosis and immunotherapy of prostate cancer

scientific article

Phage display-based generation of novel internalizing antibody fragments for immunotoxin-based treatment of acute myeloid leukemia.

scientific article

Phage display-based on-slide selection of tumor-specific antibodies on formalin-fixed paraffin-embedded human tissue biopsies.

scientific article published on 2 June 2015

Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells.

scientific article published in December 2003

Recombinant soluble human Fcgamma receptor I with picomolar affinity for immunoglobulin G.

scientific article published on 2 November 2005

Restoration of DAP Kinase Tumor Suppressor Function: A Therapeutic Strategy to Selectively Induce Apoptosis in Cancer Cells Using Immunokinase Fusion Proteins.

scientific article published on 4 October 2017

SNAP-tag technology mediates site specific conjugation of antibody fragments with a photosensitizer and improves target specific phototoxicity in tumor cells.

scientific article published on 3 November 2011

Secretion of functional anti-CD30-angiogenin immunotoxins into the supernatant of transfected 293T-cells.

scientific article published on April 2003

Short-chain fluorescent tryptophan tags for on-line detection of functional recombinant proteins

scientific article

Targeted Next-Generation Sequencing Is a Sensitive Tool for Differential Diagnosis of Myelodysplastic Syndromes in Bone Marrow Trephines

scientific article published on 19 February 2018

Targeted killing of rhabdomyosarcoma cells by a MAP-based human cytolytic fusion protein

scientific article

Targeted restoration of down-regulated DAPK2 tumor suppressor activity induces apoptosis in Hodgkin lymphoma cells

scientific article

The 140-kD isoform of CD56 (NCAM1) directs the molecular pathogenesis of ischemic cardiomyopathy.

scientific article published on 8 February 2013

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