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List of works by Johnny X Huang

A new antibiotic with potent activity targets MscL.

scientific article published on 4 February 2015

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.

scientific article published on 6 January 2016

An "Unlikely" Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI.

scientific article published on 17 May 2016

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

scientific article published on 23 June 2020

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

scientific article published on 14 June 2014

Antibacterial Low Molecular Weight Cationic Polymers: Dissecting the Contribution of Hydrophobicity, Chain Length and Charge to Activity

scientific article

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F.

scientific article published on 29 December 2015

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

scientific article published on 21 July 2015

Cationic Acrylate Oligomers Comprising Amino Acid Mimic Moieties Demonstrate Improved Antibacterial Killing Efficiency.

scientific article published on 13 December 2016

Cell- and biomarker-based assays for predicting nephrotoxicity

scientific article

Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites.

scientific article

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach

scientific article published on 30 March 2015

Drug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations.

scientific article

Drug-drug plasma protein binding interactions of ivacaftor

scientific article published on 24 February 2015

Efficient synthesis of anacardic acid analogues and their antibacterial activities.

scientific article published on 29 January 2013

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

scientific article published on 15 May 2015

Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium congestum

scientific article published on 18 August 2015

Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring

scientific article published on 05 November 2019

Identification of antitubercular benzothiazinone compounds by ligand-based design

scientific article published on 31 August 2012

Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.

scientific article

Molecular Characterization of Lipopolysaccharide Binding to Human α-1-Acid Glycoprotein

scientific article published on 20 December 2012

Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.

scientific article

Mucin Binding Reduces Colistin Antimicrobial Activity.

scientific article

Plasma Protein Binding Structure-Activity Relationships Related to the N-Terminus of Daptomycin.

scientific article

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity

scientific article published on August 2016

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

scientific article published on 2 January 2018

Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus

scientific article published on 2 September 2014

Structure aided design of chimeric antibiotics

article by Tomislav Karoli et al published April 2012 in Bioorganic & Medicinal Chemistry Letters

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

scientific article published on 23 January 2018

Structure-Function Studies of Polymyxin B Lipononapeptides

scientific article published on 02 February 2019

Structure-activity relationships for the binding of polymyxins with human α-1-acid glycoprotein

scientific article

Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.

scientific article

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

scientific article published on 01 June 2015

Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation

scientific article published in January 2015

Synthesis of essramycin and comparison of its antibacterial activity

scientific article published on 4 November 2010

Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria.

scientific article published on 12 April 2017

The Plasma Protein Binding Proteome of Ertapenem: A Novel Compound-Centric Proteomic Approach for Elucidating Drug-Plasma Protein Binding Interactions.

scientific article published on 28 September 2016

The antigenic architecture of the hemagglutinin of influenza H5N1 viruses ⬇️

scientific article published on August 7, 2013

The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach

scientific article

Truncated Latrunculins as Actin Inhibitors Targeting Plasmodium falciparum Motility and Host Cell Invasion.

scientific article published on 02 December 2016

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.

scientific article

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