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List of works by Alexander Klibanov

152 Gadolinium-labeled liposomes as a DENSE-compatible, positive MRI contrast agent for serially assessing macrophage activity and regional contractile function in the murine heart after myocardial infarction

article

3D perfusion mapping in post-infarct mice using myocardial contrast echocardiography

scientific article

5th International Symposium on Focused Ultrasound: North Bethesda, MD, USA. 28 August- 1 September 2016.

scientific article published on 21 November 2016

A Targeted Molecular Localization Imaging Method Applied to Tumor Microvasculature

scientific article published on 23 September 2020

A flow focusing microfluidic device with an integrated Coulter particle counter for production, counting and size characterization of monodisperse microbubbles

scientific article published on 01 August 2018

Acoustic attenuation by contrast agent microbubbles in superficial tissue markedly diminishes petechiae bioeffects in deep tissue

scientific article

Acoustic radiation force enhances targeted delivery of ultrasound contrast microbubbles: in vitro verification

scientific article (publication date: March 2005)

Acoustic radiation force in vivo: a mechanism to assist targeting of microbubbles

scientific article (publication date: October 1999)

All-optical photoacoustic microscopy based on plasmonic detection of broadband ultrasound

scientific article (publication date: 12 October 2015)

Analysis of focused ultrasound-induced blood-brain barrier permeability in a mouse model of Alzheimer's disease using two-photon microscopy

scientific article

Analysis of in vitro transfection by sonoporation using cationic and neutral microbubbles

scientific article

Assessment of endogenous and therapeutic arteriogenesis by contrast ultrasound molecular imaging of integrin expression

scientific article

Augmentation of brain tumor interstitial flow via focused ultrasound promotes brain-penetrating nanoparticle dispersion and transfection

scientific article published on 01 May 2020

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

scientific article

Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow

scientific article

Binding dynamics of targeted microbubbles in response to modulated acoustic radiation force

scientific article

Broadband time-domain reflectometry measurement of attenuation and phase velocity in highly attenuating suspensions with application to the ultrasound contrast medium Albunex

scientific article published on 01 August 2000

Changes in cell fate determine the regenerative and functional capacity of the developing kidney before and after release of obstruction

scientific article published on 05 December 2018

Changes in the echoes from ultrasonic contrast agents with imaging parameters

scientific article

Closed-loop feedback control of microbubble diameter from a flow-focusing microfluidic device

scientific article published on 07 May 2020

Co-administration of Microbubbles and Drugs in Ultrasound-Assisted Drug Delivery: Comparison with Drug-Carrying Particles

scientific article

Correction: A flow focusing microfluidic device with an integrated Coulter particle counter for production, counting and size characterization of monodisperse microbubbles

scientific article published on 01 May 2019

Deformable gas-filled microbubbles targeted to P-selectin

scientific article

Destruction of contrast agent microbubbles in the ultrasound field: the fate of the microbubble shell and the importance of the bubble gas content

scientific article published on 01 May 2002

Detection of individual microbubbles of an ultrasound contrast agent: fundamental and pulse inversion imaging

scientific article

Detection of individual microbubbles of ultrasound contrast agents: imaging of free-floating and targeted bubbles

scientific article

Development of target-specific liposomes for delivering small molecule drugs after reperfused myocardial infarction

scientific article

Direct Video-Microscopic Observation of the Dynamic Effects of Medical Ultrasound on Ultrasound Contrast Microspheres

scientific article published on 01 December 1998

Dual frequency method for simultaneous translation and real-time imaging of ultrasound contrast agents within large blood vessels

scientific article

Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis.

scientific article published on 2 November 2017

Dual targeting improves microbubble contrast agent adhesion to VCAM-1 and P-selectin under flow

scientific article

Early-Stage Alzheimer Disease Image-guided Therapy Clinical Trial Serendipity: Glymphatic Efflux and Prolonged Meningeal Venous Permeability Enhancement

scientific article published on 05 January 2021

Effect of microbubble ligation to cells on ultrasound signal enhancement: implications for targeted imaging

scientific article

Efficacy of Sonothrombolysis Using Microbubbles Produced by a Catheter-Based Microfluidic Device in a Rat Model of Ischemic Stroke

scientific article published on 28 January 2019

Enhanced targeting of ultrasound contrast agents using acoustic radiation force

scientific article

Evaluation of pharmacokinetic and pharmacodynamic profiles of liposomes for the cell type-specific delivery of small molecule drugs

scientific article published on 25 July 2017

Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification

scientific article published on 7 July 2017

Focused in vivo delivery of plasmid DNA to the porcine vascular wall via intravascular ultrasound destruction of microbubbles

scientific article

Focused ultrasound-mediated drug delivery from microbubbles reduces drug dose necessary for therapeutic effect on neointima formation--brief report

scientific article

Formation of Microbubbles for Targeted Ultrasound Contrast Imaging: Practical Translation Considerations

scientific article published on 04 January 2019

From Anatomy to Functional and Molecular Biomarker Imaging and Therapy: Ultrasound Is Safe, Ultrafast, Portable, and Inexpensive

scientific article published on 01 September 2020

High-resolution myocardial perfusion imaging in mice with high-frequency echocardiographic detection of a depot contrast agent

scientific article published in February 2007

Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation

scientific article

Imaging tumor angiogenesis with contrast ultrasound and microbubbles targeted to alpha(v)beta3.

scientific article

Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects

scientific article published on 14 November 2019

In Vitro Sonothrombolysis Enhancement by Transiently Stable Microbubbles Produced by a Flow-Focusing Microfluidic Device

scientific article published on 30 November 2017

In vivo imaging of microfluidic-produced microbubbles

scientific article

In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects

scientific article published on 01 January 2020

Influence of microbubble surface charge on capillary transit and myocardial contrast enhancement

scientific article

Inhibition of glioma growth by microbubble activation in a subcutaneous model using low duty cycle ultrasound without significant heating ⬇️

scientific article published on January 7, 2011

Intravascular ultrasound catheter to enhance microbubble-based drug delivery via acoustic radiation force ⬇️

scientific article published on October 1, 2012

Intravascular ultrasound detection and delivery of molecularly targeted microbubbles for gene delivery ⬇️

scientific article published on July 1, 2012

Klf4 has an unexpected protective role in perivascular cells within the microvasculature.

scientific article published on 6 April 2018

Localized in vivo model drug delivery with intravascular ultrasound and microbubbles.

scientific article

Localized ultrasound enhances delivery of rapamycin from microbubbles to prevent smooth muscle proliferation ⬇️

scientific article published on April 23, 2011

MR-guided focused ultrasound surgery, present and future ⬇️

scientific article published on August 1, 2013

Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation

scientific article

Markedly enhanced skeletal muscle transfection achieved by the ultrasound-targeted delivery of non-viral gene nanocarriers with microbubbles ⬇️

scientific article published on July 16, 2012

Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli

scientific article

Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin- and complement-mediated adherence to activated leukocytes

scientific article

Microbubble-endothelial cell interactions as a basis for assessing endothelial function

scientific article

Microbubble-enhanced ultrasound to deliver an antisense oligodeoxynucleotide targeting the human androgen receptor into prostate tumours

scientific article published on 20 October 2006

Microbubble-mediated intravascular ultrasound imaging and drug delivery

scientific article published on September 2015

Microbubbles as Ultrasound Contrast Agents for Molecular Imaging: Preparation and Application ⬇️

scientific article published on August 1, 2012

Microbubbles in ultrasound-triggered drug and gene delivery

scientific article

Microbubbles induce renal hemorrhage when exposed to diagnostic ultrasound in anesthetized rats

scientific article published on 01 November 2002

Microglial Cells Contribute to Endogenous Brain Defenses after Acute Neonatal Focal Stroke ⬇️

scientific article published on September 7, 2011

Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo

scientific article

Microvascular remodeling and accelerated hyperemia blood flow restoration in arterially occluded skeletal muscle exposed to ultrasonic microbubble destruction

scientific article

Modulating targeted adhesion of an ultrasound contrast agent to dysfunctional endothelium

scientific article published on 01 September 2002

Molecular imaging of atherosclerotic plaque targeted to oxidized LDL receptor LOX-1 using magnetic resonance

Molecular imaging of atherosclerotic plaques targeted to oxidized LDL receptor LOX-1 by SPECT/CT and magnetic resonance

scientific article

Monocyte and/or macrophage infiltration of heart after myocardial infarction: MR imaging by using T1-shortening liposomes

scientific article

Muscle contraction, but not insulin, increases microvascular blood volume in the presence of free fatty acid-induced insulin resistance

scientific article

Muscle-derived extracellular superoxide dismutase inhibits endothelial activation and protects against multiple organ dysfunction syndrome in mice

scientific article published on 2 October 2017

Nanobody-coupled microbubbles as novel molecular tracer

scientific article

Non-Invasive, Focal Disconnection of Brain Circuitry Using Magnetic Resonance-Guided Low-Intensity Focused Ultrasound to Deliver a Neurotoxin

scientific article

Non-invasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound.

scientific article

Noninvasive assessment of angiogenesis by ultrasound and microbubbles targeted to alpha(v)-integrins

scientific article

Noninvasive imaging of myocardial reperfusion injury using leukocyte-targeted contrast echocardiography

scientific article

Noninvasive ultrasound imaging of inflammation using microbubbles targeted to activated leukocytes

scientific article

Novel Focused Ultrasound Gene Therapy Approach Noninvasively Restores Dopaminergic Neuron Function in a Rat Parkinson's Disease Model

scientific article

Nucleic acid delivery with microbubbles and ultrasound.

scientific article

Optical Verification of Microbubble Response to Acoustic Radiation Force in Large Vessels With In Vivo Results

scientific article

Optical and acoustical observations of the effects of ultrasound on contrast agents

scientific article

Oscillatory Dynamics and In Vivo Photoacoustic Imaging Performance of Plasmonic Nanoparticle-Coated Microbubbles

scientific article

Phagocytic activity of neuronal progenitors regulates adult neurogenesis

scientific article

Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion

scientific article

Plectin-targeted liposomes enhance the therapeutic efficacy of a PARP inhibitor in the treatment of ovarian cancer.

scientific article

Preparation, Administration, and Assessment of In vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes

scientific article published on 30 July 2020

Pulsed ultrasound attenuates the hyperglycemic exacerbation of myocardial ischemia-reperfusion injury

scientific article published on 02 November 2019

Real-Time Technique for Improving Molecular Imaging and Guiding Drug Delivery in Large Blood Vessels: In Vitro and Ex Vivo Results ⬇️

scientific article published on April 26, 2011

Reducing Neointima Formation in a Swine Model with IVUS and Sirolimus Microbubbles

scientific article

Selectin ligands promote ultrasound contrast agent adhesion under shear flow

scientific article

Shear forces from flow are responsible for a distinct statistical signature of adherent microbubbles in large vessels.

scientific article

Simultaneous integrin alphavbeta3 and glycoprotein IIb/IIIa inhibition causes reduction in infarct size in a model of acute coronary thrombosis and primary angioplasty

scientific article

Sonoselective transfection of cerebral vasculature without blood-brain barrier disruption

scientific article published on 02 March 2020

Synthesis and Testing of Modular Dual-Modality Nanoparticles for Magnetic Resonance and Multispectral Photoacoustic Imaging

scientific article

Synthesis and characterization of transiently stable albumin-coated microbubbles via a flow-focusing microfluidic device

scientific article

Targeted Gene Transfection from Microbubbles into Vascular Smooth Muscle Cells Using Focused, Ultrasound-Mediated Delivery ⬇️

scientific article published on September 1, 2010

Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry

scientific article published on 27 September 2020

Targeted Ultrasound Contrast Imaging of Tumor Vasculature With Positively Charged Microbubbles

scientific article published on 18 June 2020

Targeted delivery of nanoparticles bearing fibroblast growth factor-2 by ultrasonic microbubble destruction for therapeutic arteriogenesis

scientific article

Targeted gene transfer to the brain via the delivery of brain-penetrating DNA nanoparticles with focused ultrasound

scientific article

Targeted in vivo labeling of receptors for vascular endothelial growth factor: approach to identification of ischemic tissue

scientific article published on 23 June 2003

Targeted tissue transfection with ultrasound destruction of plasmid-bearing cationic microbubbles

scientific article

Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow

scientific article

Targeting and ultrasound imaging of microbubble-based contrast agents

scientific article published on 01 August 1999

Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease

scientific article

Targeting of microbubbles: contrast agents for ultrasound molecular imaging.

scientific article published on 20 December 2017

Targeting of ultrasound contrast material. An in vitro feasibility study

scientific article published on January 1, 1997

Targeting of ultrasound contrast material: Selective imaging of microbubbles in vitro ⬇️

scientific article published on 01 April 1998

The Use of Acoustic Radiation Force Decorrelation-Weighted Pulse Inversion for Enhanced Ultrasound Contrast Imaging

scientific article

Therapeutic arteriogenesis by ultrasound-mediated VEGF165 plasmid gene delivery to chronically ischemic skeletal muscle

scientific article published on 21 June 2007

Ultra-Low-Dose Ultrasound Molecular Imaging for the Detection of Angiogenesis in a Mouse Murine Tumor Model: How Little Can We See?

scientific article

Ultrasonic imaging of tumor angiogenesis using contrast microbubbles targeted via the tumor-binding peptide arginine-arginine-leucine

scientific article published on January 2005

Ultrasonic microbubble destruction stimulates therapeutic arteriogenesis via the CD18-dependent recruitment of bone marrow-derived cells

scientific article

Ultrasound Assessment of Inflammation and Renal Tissue Injury With Microbubbles Targeted to P-Selectin ⬇️

scientific article published on October 23, 2001

Ultrasound Molecular Imaging of Inflammation in Mouse Abdominal Aorta

scientific article

Ultrasound imaging of acute cardiac transplant rejection with microbubbles targeted to intercellular adhesion molecule-1

scientific article published on 30 June 2003

Ultrasound in Radiology: From Anatomic, Functional, Molecular Imaging to Drug Delivery and Image-Guided Therapy

scientific article

Ultrasound-Mediated Vascular Gene Transfection by Cavitation of Endothelial-Targeted Cationic Microbubbles ⬇️

scientific article published on December 1, 2012

Ultrasound-based measurement of molecular marker concentration in large blood vessels: a feasibility study

scientific article

Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease ⬇️

scientific article published on November 8, 2012

Ultrasound-microbubble-induced neovascularization in mouse skeletal muscle

scientific article

Ultrasound-triggered release of materials entrapped in microbubble–liposome constructs: A tool for targeted drug delivery ⬇️

scientific article published on August 4, 2010

Ultrasound-triggered tumor therapy with doxorubicin-liposome-microbubble complexes in a subcutaneous murine colon adenocarcinoma model.

scientific article published on 30 June 2015

Validation of Normalized Singular Spectrum Area as a Classifier for Molecularly Targeted Microbubble Adherence

scientific article published on 19 June 2019

scVEGF microbubble ultrasound contrast agents: a novel probe for ultrasound molecular imaging of tumor angiogenesis

scientific article

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