List of works - Thorsten Mielke

Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

scientific article published on 02 July 2019

Cryo-EM structure of the Shigella type III needle complex

scientific article published on 24 February 2020

Cryo-EM structures reveal intricate Fe-S cluster arrangement and charging in Rhodobacter capsulatus formate dehydrogenase

scientific article published on 20 April 2020

Dnmt1 has de novo activity targeted to transposable elements

scientific article published on 17 June 2021

Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma

scientific article published on 28 October 2020

Footprint-free human fetal foreskin derived iPSCs: A tool for modeling hepatogenesis associated gene regulatory networks

scientific article published on 24 July 2017

Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6.

scientific article published on 8 January 2018

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.

scientific article

Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ

scientific article

Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses

scientific article published on 02 August 2021

Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution

scientific article

Structural mechanism of CRL4‐instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor

scientific article published in 2023

Structural transitions during the scaffolding-driven assembly of a viral capsid

scientific article published on 24 October 2019

Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon

scientific article published on 17 June 2022

Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide

scientific article published on 24 September 2021

The role of Helicobacter pylori DnaA domain I in orisome assembly on a bipartite origin of chromosome replication

scientific article published on 05 December 2019

List of works by Thorsten Mielke

Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

Cryo-EM structure of the Shigella type III needle complex

Cryo-EM structures reveal intricate Fe-S cluster arrangement and charging in Rhodobacter capsulatus formate dehydrogenase

Dnmt1 has de novo activity targeted to transposable elements

Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma

Footprint-free human fetal foreskin derived iPSCs: A tool for modeling hepatogenesis associated gene regulatory networks

Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6.

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.

Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ

Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses

Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution

Structural mechanism of CRL4‐instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor

Structural transitions during the scaffolding-driven assembly of a viral capsid

Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon

Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide

The role of Helicobacter pylori DnaA domain I in orisome assembly on a bipartite origin of chromosome replication