Search filters

List of works by Britt Wildemann

* Demineralized Bone Matrix as a Carrier for Bone Morphogenetic Protein-2: Burst Release Combined with Long-Term Binding and Osteoinductive Activity Evaluated In Vitro and In Vivo

scientific article published on 29 March 2017

A new electrochemically graded hydroxyapatite coating for osteosynthetic implants promotes implant osteointegration in a rat model

article

A new model of implant-related osteomyelitis in rats

scientific article published in October 2003

A pilot study investigating the histology and growth factor content of human non-union tissue

scientific article published on 27 August 2014

A short artificial antimicrobial peptide shows potential to prevent or treat bone infections

scientific article

Accumulation of homocysteine by decreasing concentrations of folate, vitamin B12 and B6 does not influence the activity of human osteoblasts in vitro

scientific article published on 4 July 2007

An investigation of BMP-7 mediated alterations to BMP signalling components in human tenocyte-like cells

scientific article published on 11 July 2016

Analysis of parameters influencing the release of antibiotics mixed with bone grafting material using a reliable mixing procedure

scientific article

Aprotinin application has no negative effect on osseous implant integration: a biomechanical and histomorphometric investigation in a rat model

scientific article published on 13 February 2008

Assessment of Bones Deficient in Fibrillin-1 Microfibrils Reveals Pronounced Sex Differences

scientific article published on 01 December 2019

BMP-2 and BMP-7 affect human rotator cuff tendon cells in vitro

scientific article published on 30 March 2011

Biodegradable poly(D,L-lactide) coating of implants for continuous release of growth factors

scientific article

Biodegradable polylactide membranes for bone defect coverage: biocompatibility testing, radiological and histological evaluation in a sheep model

scientific article published in August 2006

Bisphosphonates incorporated in a poly(D,L-lactide) implant coating inhibit osteoclast like cells in vitro

scientific article published in December 2007

Bone morphogenetic protein-2 coating of titanium implants increases biomechanical strength and accelerates bone remodeling in fracture treatment: a biomechanical and histological study in rats

scientific article published in June 2002

Bone morphogenetic proteins in critical-size bone defects: what are the options?

scientific article published in December 2009

Bone morphogenetic proteins - 7 and - 2 in the treatment of delayed osseous union secondary to bacterial osteitis in a rat model

scientific article published on 27 July 2018

Burst Release of Antibiotics Combined with Long-Term Release of Silver Targeting Implant-Associated Infections: Design, Characterization and in vitro Evaluation of Novel Implant Hybrid Surface

scientific article published on 21 November 2019

Carrier systems and application of growth factors in orthopaedics

scientific article published on September 2008

Changing the release kinetics of gentamicin from poly(D,L-lactide) implant coatings using only one polymer

scientific article published in March 2011

Characteristics and stimulation potential with BMP-2 and BMP-7 of tenocyte-like cells isolated from the rotator cuff of female donors

scientific article

Characterization of a rat osteotomy model with impaired healing

scientific article

Characterization of tendon cell cultures of the human rotator cuff

article

Chronic CCl4 intoxication causes liver and bone damage similar to the human pathology of hepatic osteodystrophy: a mouse model to analyse the liver-bone axis

scientific article published on January 2014

Cocultures of osteoblasts and osteoclasts are influenced by local application of zoledronic acid incorporated in a poly(D,L-lactide) implant coating

scientific article

Collective review: bioactive implants coated with poly(D,L-lactide) and growth factors IGF-I, TGF-beta1, or BMP-2 for stimulation of fracture healing

scientific article

Comparative Analysis of Different Platelet Lysates and Platelet Rich Preparations to Stimulate Tendon Cell Biology: An In Vitro Study

scientific article published on 10 January 2018

Current State of Bone Adhesives-Necessities and Hurdles

scientific article published on 30 November 2019

Designing biomimetic scaffolds for bone regeneration: why aim for a copy of mature tissue properties if nature uses a different approach?

article

Developmental expression of nitric oxide/cyclic GMP synthesizing cells in the nervous system of Drosophila melanogaster

scientific article published in January 1999

Die lokale Freisetzung von IGF-I und TGF-b1 aus einer biodegradierbaren Poly(D,L-Lactid) Beschichtung von Implantaten beschleunigt die Frakturheilung

article

Differences in the fusion and resorption activity of human osteoclasts after stimulation with different growth factors released from a polylactide carrier

scientific article published on 14 October 2004

Different Achilles Tendon Pathologies Show Distinct Histological and Molecular Characteristics

scientific article published on 30 January 2018

Do Matrix Metalloproteases and Tissue Inhibitors of Metalloproteases in Tenocytes of the Rotator Cuff Differ with Varying Donor Characteristics?

scientific article published on 9 June 2015

Do patient age and sex influence tendon cell biology and clinical/radiographic outcomes after rotator cuff repair?

scientific article published on 8 January 2015

Editorial of Special Issue: Biological Basis of Musculoskeletal Regeneration 2019

scientific article published on 19 August 2020

Effect of Mechanical Stimulation on Osteoblast- and Osteoclast-Like Cells in vitro

Effect of a novel nonviral gene delivery of BMP-2 on bone healing

scientific article published on 11 November 2012

Effect of local zoledronate on implant osseointegration in a rat model

scientific article

Effect of β-tricalcium phosphate coated with zoledronic acid on human osteoblasts and human osteoclasts in vitro

scientific article published on 23 August 2011

Efficacy of two different demineralised bone matrix grafts to promote bone healing in a critical-size-defect: a radiological, histological and histomorphometric study in rat femurs

scientific article published on 9 April 2014

Embryonic brain tract formation in Drosophila melanogaster

scientific article published in May 1997

Experimental Hyperhomocysteinemia Reduces Bone Quality in Rats

Experimental folate and vitamin B12 deficiency does not alter bone quality in rats

scientific article

Fibroblast and vascular endothelial growth factor coating of decellularized vascular grafts stimulates undesired giant cells and graft encapsulation in a rat model

scientific article

Gentamicin coating of metallic implants reduces implant-related osteomyelitis in rats.

scientific article

Gentamycin delivered from a PDLLA coating of metallic implants

Hyperhomocysteinemia increases bone fragility and reduces osteoblast activity in adult wistar rats

Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone

scientific article

IGF-I and TGF-beta 1 incorporated in a poly(D,L-lactide) implant coating maintain their activity over long-term storage-cell culture studies on primary human osteoblast-like cells

scientific article published in August 2004

IGF-I and TGF-beta 1 incorporated in a poly(D,L-lactide) implant coating stimulates osteoblast differentiation and collagen-1 production but reduces osteoblast proliferation in cell culture

scientific article published on April 2003

Impact of Gentamicin-Loaded Bone Graft on Defect Healing in a Sheep Model

scientific article published on 04 April 2019

Impact of Laser Structuring on Medical-Grade Titanium: Surface Characterization and In Vitro Evaluation of Osteoblast Attachment

scientific article published on 24 April 2020

Improvement of fracture healing by systemic administration of growth hormone and local application of insulin-like growth factor-1 and transforming growth factor-beta1.

scientific article published in July 2002

In Vivo and In Vitro Mechanical Loading of Mouse Achilles Tendons and Tenocytes-A Pilot Study

scientific article published on 15 February 2020

In vitro testing of the osteoinductive potential of different bony allograft preparations

Influence of age on the cell biological characteristics and the stimulation potential of male human tenocyte-like cells.

scientific article published on 12 July 2012

Influence of statins locally applied from orthopedic implants on osseous integration

scientific article

Insights into S. aureus-Induced Bone Deformation in a Mouse Model of Chronic Osteomyelitis Using Fluorescence and Raman Imaging

scientific article published in 2023

Insulin-like growth factor-1 and transforming growth factor-beta1 accelerates osteotomy healing using polylactide-coated implants as a delivery system: a biomechanical and histological study in minipigs

scientific article published in January 2002

In vivo quantification of gentamicin released from an implant coating

scientific article published on 10 February 2016

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling

scientific article published on 18 October 2019

Local BMP-2 application can rescue the delayed osteotomy healing in a rat model

scientific article published on 4 December 2010

Local and controlled release of growth factors (combination of IGF-I and TGF-beta I, and BMP-2 alone) from a polylactide coating of titanium implants does not lead to ectopic bone formation in sheep muscle

scientific article published in March 2004

Local application of BMP-2 specific plasmids in fibrin glue does not promote implant fixation

scientific article

Local application of growth factors (insulin-like growth factor-1 and transforming growth factor-beta1) from a biodegradable poly(D,L-lactide) coating of osteosynthetic implants accelerates fracture healing in rats.

scientific article published in April 2001

Local application of zoledronic acid incorporated in a poly(D,L-lactide)-coated implant accelerates fracture healing in rats

scientific article published in October 2008

Local delivery of growth factors using coated suture material

article

Local gentamicin application does not interfere with bone healing in a rat model

scientific article published on 28 April 2013

Local inhibition of angiogenesis results in an atrophic non-union in a rat osteotomy model

scientific article published on 6 July 2011

Long-term effects of local growth factor (IGF-I and TGF-beta 1) treatment on fracture healing. A safety study for using growth factors

scientific article published in May 2004

Longitudinal analysis of osteogenic and angiogenic signaling factors in healing models mimicking atrophic and hypertrophic non-unions in rats

scientific article published on 24 April 2015

Modeling hepatic osteodystrophy in Abcb4 deficient mice

scientific article

New insights into tenocyte-immune cell interplay in an in vitro model of inflammation

scientific article

Nitric oxide and cyclic GMP induce vesicle release at Drosophila neuromuscular junction

scientific article published in June 1999

Poly(D,L-lactide) coating is capable of enhancing osseous integration of Schanz screws in the absence of infection

scientific article published in July 2005

Polymer coating of porcine decellularized and cross-linked aortic grafts

scientific article published in July 2010

Proliferating and differentiating effects of three different growth factors on pluripotent mesenchymal cells and osteoblast like cells

scientific article published on 20 December 2007

Prophylaxis and treatment of implant-related infections by antibiotic-coated implants: a review

scientific article

Proteasome inhibitors abrogate osteoclast differentiation and osteoclast function

scientific article published in July 2005

Quantification of growth factors in allogenic bone grafts extracted with three different methods

scientific article published on 25 October 2006

Quantification of various growth factors in different demineralized bone matrix preparations

scientific article published in May 2007

Quantification, localization, and expression of IGF-I and TGF-beta1 during growth factor-stimulated fracture healing

scientific article published in April 2004

Quantitative assessment of growth factors in reaming aspirate, iliac crest, and platelet preparation

scientific article published on 25 July 2006

Quantitative measurement of the splice variants 120 and 164 of the angiogenic peptide vascular endothelial growth factor in the time flow of fracture healing: a study in the rat

RIA fractions contain mesenchymal stroma cells with high osteogenic potency

scientific article published in December 2015

Relationship between muscle fatty infiltration and the biological characteristics and stimulation potential of tenocytes from rotator cuff tears

scientific article published on 10 September 2013

Sequential release kinetics of two (gentamicin and BMP-2) or three (gentamicin, IGF-I and BMP-2) substances from a one-component polymeric coating on implants

scientific article

Short term in vivo biocompatibility testing of biodegradable poly(D,L-lactide)--growth factor coating for orthopaedic implants

scientific article

Signaling pathway STAT1 is strongly activated by IFN-β in the pathogenesis of osteoporosis

scientific article

Simvastatin locally applied from a biodegradable coating of osteosynthetic implants improves fracture healing comparable to BMP-2 application

scientific article published on 21 May 2009

Slight changes in the mechanical stimulation affects osteoblast- and osteoclast-like cells in co-culture

scientific article published on 27 October 2013

Small animal bone healing models: standards, tips, and pitfalls results of a consensus meeting

scientific article published on 19 July 2011

Stimulation of bone healing by sustained bone morphogenetic protein 2 (BMP-2) delivery

scientific article

Stimulation of osteoblast activity by homocysteine

scientific article published on August 2008

Stimulation of osteoclast activity by low B-vitamin concentrations

article published in 2007

Synergistic effect of IGF-I and TGF-beta1 on fracture healing in rats: single versus combined application of IGF-I and TGF-beta1.

scientific article published in October 2003

Systemic versus local application of gentamicin in prophylaxis of implant-related osteomyelitis in a rat model.

scientific article

TGF-β1 as possible link between loss of bone mineral density and chronic inflammation

scientific article

Testing of antibiotic releasing implant coatings to fight bacteria in combat-associated osteomyelitis - an in-vitro study

scientific article

The angiogenic peptide pleiotrophin (PTN/HB-GAM) is expressed in fracture healing: an immunohistochemical study in rats

The effect of zoledronic acid incorporated in a poly(D,L-lactide) implant coating on osteoblasts in vitro

scientific article published in March 2007

The role of hyperhomocysteinemia as well as folate, vitamin B(6) and B(12) deficiencies in osteoporosis: a systematic review

scientific article published on January 2007

Time-Dependent Alterations of MMPs, TIMPs and Tendon Structure in Human Achilles Tendons after Acute Rupture

scientific article published on 20 October 2017

Treatment of Tibial Non-Unions - State of the Art and Future Implications

scientific article published on January 2016

Verbesserung der knöchernen Integration von Schanz’ Schrauben durch eine Poly(D,L-laktid) Beschichtung

Whither advanced therapy medicinal products?

scientific article (publication date: December 2013)

Paulina is supported by:

About Paulina

Help