List of works by Allan I. Pack

A novel BHLHE41 variant is associated with short sleep and resistance to sleep deprivation in humans

scientific article

A novel gain-of-function mutant of the cyclic GMP-dependent protein kinase egl-4 affects multiple physiological processes in Caenorhabditis elegans

scientific article

AJRCCM: 100-Year Anniversary. Sleep-Disordered Breathing: Still the New Kid on the Block

scientific article published in May 2017

Action of positive feedback related to lung inflation in the control of ventilation

scientific article published on 01 December 1982

Activation of a distinct arousal state immediately after spontaneous awakening from sleep

scientific article published in December 1997

Activity of adenosine deaminase in the sleep regulatory areas of the rat CNS

scientific journal article

Adhesion molecule increases in sleep apnea: beneficial effect of positive airway pressure and moderation by obesity.

scientific article

Advances in sleep-disordered breathing.

scientific article

Age-related changes in adenosine metabolic enzymes in sleep/wake regulatory areas of the brain.

scientific article published in February 2006

Aging impairs the unfolded protein response to sleep deprivation and leads to proapoptotic signaling

scientific article

Aging in mice reduces the ability to sustain sleep/wake states

scientific article

Aging induced endoplasmic reticulum stress alters sleep and sleep homeostasis.

scientific article

Aging is Associated With an Earlier Arrival of Reflected Waves Without a Distal Shift in Reflection Sites

scientific article published on 29 August 2016

Agreement in the scoring of respiratory events and sleep among international sleep centers

scientific article published on April 2013

Altered diurnal states in insomnia reflect peripheral hyperarousal and metabolic desynchrony: a preliminary study

scientific article published on 01 May 2018

Altered upper airway and soft tissue structures in the New Zealand Obese mouse

scientific article

Amyloid-β induces sleep fragmentation that is rescued by fatty acid binding proteins in Drosophila

scientific article published on 19 June 2016

Analysis of the QTL for sleep homeostasis in mice: Homer1a is a likely candidate

scientific article published on 2 January 2008

Application of Personalized, Predictive, Preventative, and Participatory (P4) Medicine to Obstructive Sleep Apnea. A Roadmap for Improving Care?

scientific article published on 7 July 2016

Arousal Responses during Overnight Polysomnography and their Reproducibility in Healthy Young Adults

scientific article published on 12 January 2015

Assessing REM sleep in mice using video data

scientific article

Automated Protein Localization of Blood Brain Barrier Vasculature in Brightfield IHC Images

scientific article published in February 2016

Behavior of VRG neurons during the atonia of REM sleep induced by pontine carbachol in decerebrate cats

scientific article published in October 1992

Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation

scientific article

Carotid Artery Wall Thickness in Obese and Nonobese Adults With Obstructive Sleep Apnea Before and Following Positive Airway Pressure Treatment

scientific article

Celebrating a rare privilege to announce a new editor-in-chief of the flagship journal for the sleep field

scientific article published on December 2014

Central sleep apnea

scientific article published on 01 January 2011

Changes in control of ventilation, awake and asleep, in the elderly

scientific article published in July 1986

Changes in serotonin level in the hypoglossal nucleus region during carbachol-induced atonia.

scientific article published on May 1994

Changes in upper airway size during tidal breathing in children with obstructive sleep apnea syndrome

scientific article published on 04 March 2005

Changing Faces of OSA: Treatment Effects by Cluster Designation in the Icelandic Sleep Apnea Cohort

scientific article published on 2 January 2018

Characterization of thyrotropin-releasing hormone in the central nervous system of African lungfish

scientific article published on 01 October 1988

Circulating adhesion molecules in obstructive sleep apnea and cardiovascular disease

scientific article published on 22 April 2013

Claustrophobia and adherence to CPAP treatment

scientific article published in April 2005

Consequences of comorbid insomnia symptoms and sleep-related breathing disorder in elderly subjects

scientific article published in September 2006

Dealing with a Paradigm Shift

scientific article

Depressive symptoms in patients with obstructive sleep apnea: biological mechanistic pathways

scientific article

Detection of upper airway status and respiratory events by a current generation positive airway pressure device

scientific article

Developing Biomarker Arrays Predicting Sleep and Circadian-Coupled Risks to Health

scientific article

Developing Sleep Medicine Internationally

scientific article published in September 2015

Diet/Energy Balance Affect Sleep and Wakefulness Independent of Body Weight

scientific article published on 22 June 2015

Dietary therapy mitigates persistent wake deficits caused by mild traumatic brain injury

scientific article published on December 2013

Different cyclical intermittent hypoxia severities have different effects on hippocampal microvasculature.

scientific article published on 28 April 2016

Differential sensitivity of laryngeal and pharyngeal motoneurons to iontophoretic application of serotonin

scientific article published on 01 December 1997

Effects of continuous positive airway pressure on blood pressure in patients with resistant hypertension and obstructive sleep apnea: a meta-analysis

scientific article

Effects of lung inflation on the excitability of dorsal respiratory group neurons.

scientific article published in February 1986

Estimated cost of crashes in commercial drivers supports screening and treatment of obstructive sleep apnea.

scientific article

Evocation of postural atonia and respiratory depression by pontine carbachol in the decerebrate rat.

scientific article published in November 1992

Family aggregation of upper airway soft tissue structures in normal subjects and patients with sleep apnea.

scientific article published on 06 October 2005

Functional genomics of sleep.

scientific article

Genetic Basis of Chronotype in Humans: Insights From Three Landmark GWAS.

scientific article published on February 2017

Genetic Correlation Analysis Suggests Association between Increased Self-Reported Sleep Duration in Adults and Schizophrenia and Type 2 Diabetes

scientific article published on July 2016

Genetic background has a major impact on differences in sleep resulting from environmental influences in Drosophila

scientific article published on April 2012

Genetic evidence for a role of CREB in sustained cortical arousal.

scientific article

Genetics of Sleep Disorders

scientific article

Glutamate Is a Wake-Active Neurotransmitter in Drosophila melanogaster

scientific article

Heart Failure and Sleep-Disordered Breathing--The Plot Thickens

scientific article published in September 2015

Heritability of craniofacial structures in normal subjects and patients with sleep apnea

scientific article

Heritability of insomnia symptoms in youth and their relationship to depression and anxiety

scientific article published on December 2011

High-throughput sleep phenotyping produces robust and heritable traits in Diversity Outbred mice and their founder strains

scientific article published on 19 February 2020

Identification of low-frequency variants associated with gout and serum uric acid levels

scientific article published on 9 October 2011

Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging

scientific article published on 13 May 2003

Impact of sleep and circadian disruption on energy balance and diabetes: a summary of workshop discussions

journal article published in 2015

Implementation of Sleep and Circadian Science: Recommendations from the Sleep Research Society and National Institutes of Health Workshop

scientific article

In Pursuit of Sleep-Circadian Biomarkers ⬇️

scientific article published on 5 October 2015

Insomnia complaints in lean patients with obstructive sleep apnea negatively affect positive airway pressure treatment adherence

scientific article published on 15 December 2016

Insomnia in untreated sleep apnea patients compared to controls

scientific article published on 12 October 2011

Issues in sleep and breathing

scientific article published in October 2000

Lethargus is a Caenorhabditis elegans sleep-like state.

scientific article

Lower plasma choline levels are associated with sleepiness symptoms.

scientific article published on 26 October 2017

Macromolecule biosynthesis: a key function of sleep

scientific article published on 14 August 2007

Mechanisms of ventilatory periodicities

scientific article

Methylation Changes in DNA in Patients with Obstructive Sleep Apnea.

scientific article published on April 2016

Molecular mechanisms of sleep and wakefulness.

scientific article published on January 2008

Multiple mechanisms limit the duration of wakefulness in Drosophila brain

scientific article published on 5 September 2006

Nocturnal sweating--a common symptom of obstructive sleep apnoea: the Icelandic sleep apnoea cohort

scientific article published on 14 May 2013

Novel method for high-throughput phenotyping of sleep in mice.

scientific article

Objective snoring time and carotid intima-media thickness in non-apneic female snorers.

scientific article published on 6 December 2016

Obstructive Sleep Apnea: Update and Future

scientific article published on 5 October 2016

Obstructive sleep apnea and cognitive impairment: addressing the blood-brain barrier

scientific article

Obstructive sleep apnoea treatment and fasting lipids: a comparative effectiveness study

scientific article

Occupational screening for obstructive sleep apnea in commercial drivers

scientific article published on 13 May 2004

Opportunities for utilizing polysomnography signals to characterize obstructive sleep apnea subtypes and severity

P4 medicine approach to obstructive sleep apnoea.

scientific article published on 5 May 2017

POINT: Does Laboratory Polysomnography Yield Better Outcomes Than Home Sleep Testing? Yes.

scientific article published in August 2015

Pleiotropic genetic effects influencing sleep and neurological disorders.

scientific article published on February 2017

Predictors of continuous positive airway pressure use during the first week of treatment

scientific article

Problems associated with short sleep: bridging the gap between laboratory and epidemiological studies

scientific article

Prospective observation on the association of snoring with subclinical changes in carotid atherosclerosis over four years.

scientific article

Proteomic analysis of the effects and interactions of sleep deprivation and aging in mouse cerebral cortex

scientific article published on 5 October 2007

Pulmonary stretch receptor relay neurones of the cat: location and contralateral medullary projections

scientific article published on 01 February 1987

RNA-seq analysis of galaninergic neurons from ventrolateral preoptic nucleus identifies expression changes between sleep and wake

scientific article published on 14 September 2020

Rebuttal From Dr Pack

scientific article published in August 2015

Reliability of a single objective measure in assessing sleepiness

journal article published in 2012

Risk factors for sleep-disordered breathing in pregnancy.

scientific article published on 21 November 2013

Role of Homer proteins in the maintenance of sleep-wake states

scientific article

Role of medullary inspiratory neurones in the control of the diaphragm during oesophageal stimulation in cats

scientific article published in October 1987

Running-induced anxiety is dependent on increases in hippocampal neurogenesis.

scientific article

Serotonergic excitatory drive to hypoglossal motoneurons in the decerebrate cat ⬇️

scientific article published on May 25, 1992

Shortened sleep duration does not predict obesity in adolescents

scientific article

Should a pharmaceutical be approved for the broad indication of excessive sleepiness?

scientific article

Simulating obstructive sleep apnea patients' oxygenation characteristics into a mouse model of cyclical intermittent hypoxia.

scientific article

Simultaneous assessment of ecto- and cytosolic-5'-nucleotidase activities in brain micropunches

scientific article published in December 2000

Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences.

scientific article published on February 2017

Sleep and memory: a molecular perspective.

scientific article

Sleep apnea in total joint arthroplasty patients and the role for cardiac biomarkers for risk stratification: an exploration of feasibility.

scientific article published on March 2016

Sleep deprivation induces the unfolded protein response in mouse cerebral cortex

scientific article published in March 2005

Sleep deprivation selectively impairs memory consolidation for contextual fear conditioning.

scientific article

Sleep disorders, public health, and public safety.

scientific article published in December 2011

Sleep duration and body mass index in twins: a gene-environment interaction

scientific article

Sleep duration and depressive symptoms: a gene-environment interaction

scientific article

Sleep in children with Williams Syndrome

scientific article published on 21 September 2011

Sleep terrors in childhood.

scientific article

Sleep-disordered breathing and daytime napping are associated with maternal hyperglycemia

scientific article published on 25 January 2013

Sleepiness and relationships in obstructive sleep apnea

scientific article published in April 2006

Slow-paced respiration therapy to treat symptoms in pulmonary arterial hypertension.

scientific article published on 21 November 2016

Social jet lag, chronotype and body mass index in 14-17-year-old adolescents.

scientific article

Statistical Learning with Time Series Dependence: An Application to Scoring Sleep in Mice

scientific article

Structural Variation Shapes the Landscape of Recombination in Mouse.

scientific article published on June 2017

Suppression of hypoglossal motoneurons during the carbachol-induced atonia of REM sleep is not caused by fast synaptic inhibition

scientific article published in May 1993

Symptomless Multi-Variable Apnea Prediction Index Assesses Obstructive Sleep Apnea Risk and Adverse Outcomes in Elective Surgery.

scientific article published on March 2017

Symptoms of insomnia among patients with obstructive sleep apnea before and after two years of positive airway pressure treatment

scientific article published on December 2013

The different clinical faces of obstructive sleep apnoea: a cluster analysis.

scientific article published on 3 September 2014

The effects of serotonin antagonists in an animal model of sleep-disordered breathing

scientific article published on 01 February 1996

The energy hypothesis of sleep revisited

scientific article

The impact of obstructive sleep apnea on nonalcoholic fatty liver disease in patients with severe obesity

scientific article published on 16 February 2016

The interaction of obstructive sleep apnea and obesity on the inflammatory markers C-reactive protein and interleukin-6: the Icelandic Sleep Apnea Cohort

scientific article

The nexus of Aβ, aging, and sleep.

scientific article published in September 2012

The prevalence of work-related sleep problems

scientific article published in January 1995

The responses of I beta cells to increases in the rate of lung inflation.

scientific article published in August 1981

Time of day regulates subcellular trafficking, tripartite synaptic localization, and polyadenylation of the astrocytic Fabp7 mRNA

scientific article published on January 2012

Tongue fat and its relationship to obstructive sleep apnea.

scientific article

Tongue fat infiltration in obese versus lean Zucker rats

scientific article

Transcriptional Profiling of Cholinergic Neurons From Basal Forebrain Identifies Changes in Expression of Genes Between Sleep and Wake.

scientific article

Transcriptional Signatures of Sleep Duration Discordance in Monozygotic Twins

scientific article published on January 2017

Update on Sleep and Its Disorders ⬇️

scientific article published on January 1, 2011

Upper airway size analysis by magnetic resonance imaging of children with obstructive sleep apnea syndrome

scientific article published on 11 October 2002

Validation of the Nox-T3 Portable Monitor for Diagnosis of Obstructive Sleep Apnea in Chinese Adults.

scientific article published on 26 January 2017

What are microarrays teaching us about sleep?

scientific article

What can sleep medicine do?

scientific article published on 15 June 2013

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