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List of works by James M. Fleckenstein

A Role for Salivary Peptides in the Innate Defense Against Enterotoxigenic Escherichia coli.

scientific article published on 8 March 2018

Blood Group O-Dependent Cellular Responses to Cholera Toxin: Parallel Clinical and Epidemiological Links to Severe Cholera.

scientific article published on 9 May 2016

CEACAMs serve as toxin-stimulated receptors for enterotoxigenic Escherichia coli

scientific article published on 02 November 2020

Characterization of enterotoxigenic Escherichia coli strains isolated from the massive multi-pathogen gastroenteritis outbreak in the Antofagasta region following the Chilean earthquake, 2010.

scientific article

Comparative genomic analysis and molecular examination of the diversity of enterotoxigenic Escherichia coli isolates from Chile

scientific article published on 20 November 2019

Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli

scientific article

Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli

scientific article published on 22 November 2019

Conservation and immunogenicity of novel antigens in diverse isolates of enterotoxigenic Escherichia coli.

scientific article

Contribution of the highly conserved EaeH surface protein to enterotoxigenic Escherichia coli pathogenesis.

scientific article

Cooperative Role of Antibodies against Heat-Labile Toxin and the EtpA Adhesin in Preventing Toxin Delivery and Intestinal Colonization by Enterotoxigenic Escherichia coli

scientific article published on August 8, 2012

Designing vaccines to neutralize effective toxin delivery by enterotoxigenic Escherichia coli.

scientific article

Directed Evaluation of Enterotoxigenic Escherichia coli Autotransporter Proteins as Putative Vaccine Candidates

scientific article published on December 6, 2011

Directed delivery of heat-labile enterotoxin by enterotoxigenic Escherichia coli.

scientific article published on September 2006

Dynamic Interactions of a Conserved Enterotoxigenic Escherichia coli Adhesin with Intestinal Mucins Govern Epithelium Engagement and Toxin Delivery

scientific article published on 10 October 2016

EatA, an immunogenic protective antigen of enterotoxigenic Escherichia coli, degrades intestinal mucin.

scientific article

Enterotoxigenic Escherichia coli Infections

scientific article published on 04 March 2019

Enterotoxigenic Escherichia coli blood group A interactions intensify diarrheal severity.

scientific article

Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia

scientific article published in 2022

Enterotoxigenic Escherichia coli secretes a highly conserved mucin-degrading metalloprotease to effectively engage intestinal epithelial cells.

scientific article

Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity

scientific article published on 01 July 2019

Enterotoxigenic Escherichia coli: Orchestrated host engagement.

scientific article published on 25 July 2013

Examination of the Enterotoxigenic Escherichia coli Population Structure during Human Infection.

scientific article published on 9 June 2015

Heat-labile enterotoxin promotes Escherichia coli adherence to intestinal epithelial cells.

scientific article published on 31 October 2008

How genomics can be used to understand host susceptibility to enteric infection, aiding in the development of vaccines and immunotherapeutic interventions

scientific article published on 29 January 2019

Human Experimental Challenge With Enterotoxigenic Escherichia coli Elicits Immune Responses to Canonical and Novel Antigens Relevant to Vaccine Development

scientific article published on 01 September 2018

Identification and molecular characterization of EatA, an autotransporter protein of enterotoxigenic Escherichia coli.

scientific article published on March 2004

Identification of a gene within a pathogenicity island of enterotoxigenic Escherichia coli H10407 required for maximal secretion of the heat-labile enterotoxin.

scientific article

Identification of a two-partner secretion locus of enterotoxigenic Escherichia coli.

scientific article published in April 2006

Immunogenicity and Protective Efficacy against Enterotoxigenic Escherichia coli Colonization following Intradermal, Sublingual, or Oral Vaccination with EtpA Adhesin

scientific article published on 25 May 2016

Incidental discovery of emphysematous cystitis

scientific article published on 01 August 1998

Infectious agents of food- and water-borne illnesses.

scientific article published on September 2010

Insights into enterotoxigenic Escherichia coli diversity in Bangladesh utilizing genomic epidemiology

scientific article

Interaction of an uuter membrane protein of enterotoxigenic Escherichia coli with cell surface heparan sulfate proteoglycans.

scientific article published on March 2002

Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection

scientific article published on 28 August 2019

Lingual leishmaniasis complicating visceral disease.

scientific article published in May 2010

Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model

scientific article published on 20 February 2020

Molecular Determinants of Enterotoxigenic Escherichia coli Heat-Stable Toxin Secretion and Delivery.

scientific article published on 25 October 2018

Molecular mechanisms of enterotoxigenic Escherichia coli infection.

scientific article published on 31 October 2009

Novel antigens for enterotoxigenic Escherichia coli vaccines

scientific article

Outer membrane vesicles induce immune responses to virulence proteins and protect against colonization by enterotoxigenic Escherichia coli.

scientific article published on 7 September 2011

Overcoming Enterotoxigenic Escherichia coli Pathogen Diversity: Translational Molecular Approaches to Inform Vaccine Design.

scientific article published on January 2016

Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection

scientific article published on 07 May 2020

Providing Structure to Enterotoxigenic Escherichia coli Vaccine Development.

scientific article published on 24 May 2017

Purification of recombinant high molecular weight two-partner secretion proteins from Escherichia coli

scientific article published on 2 July 2009

The intriguing interaction of Escherichia coli with the host environment and innovative strategies to interfere with colonization: A summary of the 2019 E. coli and the Mucosal Immune System meeting

scientific article published on 02 October 2020

Transcriptional Modulation of Enterotoxigenic Escherichia coli Virulence Genes in Response to Epithelial Cell Interactions

scientific article published on October 31, 2012

Vaccination with EtpA glycoprotein or flagellin protects against colonization with enterotoxigenic Escherichia coli in a murine model.

scientific article