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List of works by Kazuhisa Nakayama

A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells

scientific article

A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation.

scientific article published on November 1995

ADP-ribosylation factor-1 is sensitive to N-ethylmaleimide.

scientific article published in December 1998

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors

scientific article

ARF1 and ARF3 are required for the integrity of recycling endosomes and the recycling pathway

scientific article published on 05 September 2012

ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells.

scientific article

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner

scientific article

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

scientific article published in January 2015

Activation of histidine decarboxylase through post-translational cleavage by caspase-9 in a mouse mastocytoma P-815.

scientific article published on 14 March 2007

Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin

scientific article (publication date: 19 May 2000)

Alteration of transbilayer phospholipid compositions is involved in cell adhesion, cell spreading, and focal adhesion formation.

scientific article published on 9 June 2016

Anterograde trafficking of ciliary MAP kinase-like ICK/CILK1 by the IFT machinery is required for intraciliary retrograde protein trafficking

scientific article published on 29 July 2020

Architecture of the IFT ciliary trafficking machinery and interplay between its components

scientific article published on 26 May 2020

Architectures of multisubunit complexes revealed by a visible immunoprecipitation assay using fluorescent fusion proteins

scientific article published on 11 May 2015

Arfaptins are localized to the trans-Golgi by interaction with Arl1, but not Arfs.

scientific article

BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex

scientific article published on 28 March 2018

BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: its localization to recycling endosomes and implication in the endosome integrity

scientific article

C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization

scientific article published on 01 March 2019

COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions

scientific article

Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells

scientific journal article

Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.

scientific article published on 11 January 2017

Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.

scientific article published on 20 December 2017

Ciliopathy-associated mutations of IFT122 impair ciliary protein trafficking but not ciliogenesis

scientific article published on 6 December 2017

Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.

scientific article published on September 2015

Cloning and Functional Expression of a Novel Endoprotease Involved in Prohormone Processing at Dibasic Sites1 ⬇️

scientific article published on June 1, 1991

Convergence of cell cycle regulation and growth factor signals on GRASP65

scientific article (publication date: 17 June 2005)

Differential effects of depletion of ARL1 and ARFRP1 on membrane trafficking between the trans-Golgi network and endosomes

scientific article

Distinct roles of Rab11 and Arf6 in the regulation of Rab11-FIP3/arfophilin-1 localization in mitotic cells.

scientific article

Dominant-negative mutant of BIG2, an ARF-guanine nucleotide exchange factor, specifically affects membrane trafficking from the trans-Golgi network through inhibiting membrane association of AP-1 and GGA coat proteins

scientific article (publication date: 7 June 2002)

Dual control of membrane targeting by PtdIns(4)P and ARF

scientific article published on 01 October 2004

Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network

scientific article

EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis.

scientific article

Effects of propeptide deletion on human renin secretion from mouse pituitary AtT-20 cells.

scientific article published on May 1990

Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue-type mast cells.

scientific article published on 31 March 2008

Expression of BIG2 and analysis of its function in mammalian cells

scientific article published on 01 January 2005

Expression of the mouse macrophage cystine transporter in Xenopus laevis oocytes

scientific article published in August 1991

Functional cross-talk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4.

scientific article

Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic.

scientific article

Furin has the proalbumin substrate specificity and serpin inhibitory properties of an in situ hepatic convertase

scientific article published on 01 January 1994

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

scientific article

GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.

scientific article published on 2 December 2003

GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER transport involved in regulation of lipid homeostasis

scientific article published on 01 January 2011

GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors

scientific article

GM130 is a parallel tetramer with a flexible rod-like structure and N-terminally open (Y-shaped) and closed (I-shaped) conformations

scientific journal article

Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain.

scientific article

Guanine nucleotide-exchange factors for arf GTPases: their diverse functions in membrane traffic.

scientific article

Histamine synthesis is required for granule maturation in murine mast cells.

scientific article published in October 2013

Identification and Characterization of Novel Clathrin Adaptor-related Proteins ⬇️

scientific article published on September 18, 1998

Identification and Subcellular Localization of a Novel Mammalian Dynamin-Related Protein Homologous to Yeast Vps1p and Dnm1p ⬇️

scientific article published on September 1, 1997

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

scientific journal article

Identification of a five-pass transmembrane protein family localizing in the Golgi apparatus and the ER.

scientific article published in December 2003

Immunocytochemical localization of prohormone convertases PC1/PC3 and PC2 in rat pancreatic islets

scientific article published on 01 August 1996

Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking

scientific article published on 09 May 2018

Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis

scientific article published on 14 June 2018

Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking

scientific article published on 16 January 2019

Interleukin-1 and lipopolysaccharide enhance intercellular adhesion molecule-1 expression in cell lines of human squamous cell carcinoma

scientific article published on 01 February 1997

Intermolecular and interdomain interactions of a dynamin-related GTP-binding protein, Dnm1p/Vps1p-like protein

scientific article published on 01 January 1999

Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.

scientific article published on 08 December 2016

Involvement of CD44 in mast cell proliferation during terminal differentiation

scientific article published on 9 February 2009

Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization

scientific article published on 01 January 1993

Localization of furin to the trans-Golgi network and recycling from the cell surface involves Ser and Tyr residues within the cytoplasmic domain.

scientific article published on November 1995

Mechanisms of membrane curvature generation in membrane traffic.

scientific article published on 29 February 2012

Membrane orientation of the precursor 74-kDa form of L-histidine decarboxylase.

scientific article published in May 2006

Membrane recruitment of effector proteins by Arf and Rab GTPases.

scientific article

Modulation of primary cilia length by melanin-concentrating hormone receptor 1.

scientific article published on 02 March 2016

Molecular and enzymatic properties of furin, a Kex2-like endoprotease involved in precursor cleavage at Arg-X-Lys/Arg-Arg sites.

scientific article

Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport

scientific article (publication date: May 2003)

Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex

scientific article published on 15 March 2016

Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics

scientific article published on 06 May 2015

Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation.

scientific article published on 10 November 2017

Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane

scientific article

Phospholipid-flipping activity of P4-ATPase drives membrane curvature

article published in 2018

Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway

scientific article published on 01 April 1993

Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system

scientific article published on 8 February 2017

Predominant expression of the short form of GGA3 in human cell lines and tissues.

scientific article

Processing of wild-type and mutant proinsulin-like growth factor-IA by subtilisin-related proprotein convertases.

scientific article published on March 1997

Proprotein processing activity and cleavage site selectivity of the Kex2-like endoprotease PACE4

scientific article published on 01 December 1993

Prorenin is sorted into the regulated secretory pathway independent of its processing to renin in mouse pituitary AtT-20 cells

scientific article published on 01 October 1989

Proteolytic processing of pro-opiomelanocortin occurs in acidifying secretory granules of AtT-20 cells.

scientific article published on March 1997

Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin

scientific article published on 01 August 1993

Purification and properties of extracellular poly(3-hydroxybutyrate) depolymerases from Pseudomonas lemoignei

scientific article published on 01 January 1985

Purification of recombinant soluble forms of furin produced in Chinese hamster ovary cells

scientific article published on 01 January 1994

RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly.

scientific article published on 20 April 2017

Rab11 regulates exocytosis of recycling vesicles at the plasma membrane.

scientific article published on 8 June 2012

Recruitment of Tom1L1/Srcasm to endosomes and the midbody by Tsg101.

scientific article

Recruitment of clathrin onto endosomes by the Tom1-Tollip complex

scientific article

Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes

scientific article published on 16 April 2008

Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.

scientific article

Regulation of cytokinesis by membrane trafficking involving small GTPases and the ESCRT machinery

scientific article published on 11 September 2015

Regulation of phosphatidylinositol 4-phosphate 5-kinase activity by partner proteins.

scientific article published in January 2007

Requirement of IFT-B-BBSome complex interaction in export of GPR161 from cilia

scientific article published on 17 September 2019

Restriction of mast cell proliferation through hyaluronan synthesis by co-cultured fibroblasts.

scientific article published on January 2012

Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation.

scientific article published on 6 January 2008

Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis

scientific article published on 13 April 2018

Role of ADP-ribosylation factor 6 (ARF6) in gastric acid secretion

scientific article

Role of cathepsin B as prorenin processing enzyme in human kidney

scientific article published on 01 June 1995

SNAP23/25 and VAMP2 mediate exocytic event of transferrin receptor-containing recycling vesicles.

scientific article

Sequence requirements for endoproteolytic processing of precursor proteins by furin: transfection and in vitro experiments.

scientific article published on July 1994

Shigella Targets Epithelial Tricellular Junctions and Uses a Noncanonical Clathrin-Dependent Endocytic Pathway to Spread Between Cells ⬇️

scientific article published on April 19, 2012

Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system

scientific article (publication date: 22 June 2001)

Strain-specific presence of two TGN38 isoforms and absence of TGN41 in mouse.

scientific article

Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis.

scientific article

Structural basis for recognition of acidic-cluster dileucine sequence by GGA1

scientific article

Structural basis for recognition of ubiquitinated cargo by Tom1-GAT domain

scientific article

Structure determination of GGA-GAE and gamma1-ear in complex with peptides: crystallization of low-affinity complexes in membrane traffic

scientific article published on 26 May 2005

Structure of the rat renin gene

scientific journal article

Subtype-specific trafficking of endothelin receptors

scientific article published on 01 March 2000

Testis-Specific Prohormone Convertase PC4 Processes the Precursor of Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) ⬇️

scientific article published on January 1, 1998

The cytoplasmic C-terminal region of the ATP11C variant determines its localization at the polarized plasma membrane

scientific article published on 02 September 2019

The influence of glycosylation on the fate of renin expressed in Xenopus oocytes

scientific article published on 01 July 1990

The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments

scientific article

The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane

scientific article

The structure and function of GGAs, the traffic controllers at the TGN sorting crossroads

scientific article published on October 2003

Three homologous ArfGAPs participate in coat protein I-mediated transport.

scientific article

cDNA cloning of bovine substance-K receptor through oocyte expression system.

scientific article

mRNA sequence for human cardiodilatin-atrial natriuretic factor precursor and regulation of precursor mRNA in rat atria

scientific article

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