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Authors whose works are in public domain in at least one jurisdiction

List of works by Nicholas J. Bradshaw

A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations

scientific article published in March 2017

A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins

scientific article

Aggregation of the protein TRIOBP-1 and its potential relevance to schizophrenia.

scientific article

An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure.

scientific article

Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.

scientific article published on 11 January 2018

Cloning of the promoter of NDE1, a gene implicated in psychiatric and neurodevelopmental disorders through copy number variation.

scientific article published on 11 March 2016

DISC1, PDE4B, and NDE1 at the centrosome and synapse

scientific journal article

DISC1-binding proteins in neural development, signalling and schizophrenia ⬇️

scientific article published on December 31, 2010

DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness ⬇️

scientific article published on August 5, 2011

Disrupted in Schizophrenia 1 regulates the processing of reelin in the perinatal cortex

scientific article

Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions

scientific article

NDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness

scientific article published on 14 October 2016

NDE1 and NDEL1: multimerisation, alternate splicing and DISC1 interaction

scientific article

NDE1 and NDEL1: twin neurodevelopmental proteins with similar ‘nature’ but different ‘nurture’ ⬇️

scientific article published on October 1, 2013

PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1

scientific article

Phenotypic Translation of the Disc1 Network Highlights the Role of the Nde1 Locus, with Pharmacological Implications

scholarly article by William Hennah et al published 2017 in European Neuropsychopharmacology

Protein misassembly and aggregation as potential convergence points for non-genetic causes of chronic mental illness

scientific article published on 08 August 2018

Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits

scientific article

Recent and recurrent selective sweeps of the antiviral RNAi gene Argonaute-2 in three species of Drosophila

scientific article

The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484.

scientific article published in November 2017

The TRIOBP Isoforms and Their Distinct Roles in Actin Stabilization, Deafness, Mental Illness, and Cancer

scientific article published on 27 October 2020

The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution.

scientific article

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