List of works by Salvador Fernández-Arroyo

A phase 2 trial of neoadjuvant metformin in combination with trastuzumab and chemotherapy in women with early HER2-positive breast cancer: the METTEN study

scientific article published on 02 November 2018

A systematic study of the polyphenolic composition of aqueous extracts deriving from several Cistus genus species: evolutionary relationship.

scientific article

Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome

scientific article published on 02 March 2016

Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile

scientific article

Activation of the methylation cycle in cells reprogrammed into a stem cell-like state.

scientific article published on January 2015

Alterations in plasma concentrations of energy-balance-related metabolites in patients with lung, or head & neck, cancers: Effects of radiotherapy

scientific article published on 11 December 2019

An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors

scientific article published on 01 March 2019

Antioxidant activity evaluation of new dosage forms as vehicles for dehydrated vegetables

scientific article published on 01 June 2013

Application of nanoLC-ESI-TOF-MS for the metabolomic analysis of phenolic compounds from extra-virgin olive oil in treated colon-cancer cells.

scientific article published in February 2012

Assessment of extracellular matrix-related biomarkers in patients with lower extremity artery disease

scientific article published on 31 March 2018

Bioactive Compounds from Theobroma cacao: Effect of Isolation and Safety Evaluation

scientific article published on 01 March 2019

Bioavailability study of a polyphenol-enriched extract from Hibiscus sabdariffa in rats and associated antioxidant status

scientific article published on 15 August 2012

Chemokine (C-C motif) ligand 2 and coronary artery disease: Tissue expression of functional and atypical receptors

scientific article published on 15 November 2019

Chemokine (C-C motif) ligand 2 gene ablation protects low-density lipoprotein and paraoxonase-1 double deficient mice from liver injury, oxidative stress and inflammation

scientific article published on 21 March 2019

Cistaceae aqueous extracts containing ellagitannins show antioxidant and antimicrobial capacity, and cytotoxic activity against human cancer cells.

scientific article

Cocoa and Grape Seed Byproducts as a Source of Antioxidant and Anti-Inflammatory Proanthocyanidins

scientific article

Correlation between plasma antioxidant capacity and verbascoside levels in rats after oral administration of lemon verbena extract

article

Crude phenolic extracts from extra virgin olive oil circumvent de novo breast cancer resistance to HER1/HER2-targeting drugs by inducing GADD45-sensed cellular stress, G2/M arrest and hyperacetylation of Histone H3.

scientific article published on 30 March 2011

Different behavior of polyphenols in energy metabolism of lipopolysaccharide-stimulated cells

scientific article published on 13 February 2018

Effect of Vitamin D3 on the Postprandial Lipid Profile in Obese Patients: A Non-Targeted Lipidomics Study

scientific article published on 27 May 2019

Effect of radiotherapy on activity and concentration of serum paraoxonase-1 in breast cancer patients

scientific article published on 27 November 2017

Effects of radiotherapy on plasma energy metabolites in patients with breast cancer who received neoadjuvant chemotherapy

scientific article published on 02 November 2019

Epigenetics and nutrition-related epidemics of metabolic diseases: Current perspectives and challenges

scientific article

Evaluation of different extraction approaches for the determination of phenolic compounds and their metabolites in plasma by nanoLC-ESI-TOF-MS

scientific article published on 13 October 2012

Exploring the Process of Energy Generation in Pathophysiology by Targeted Metabolomics: Performance of a Simple and Quantitative Method.

scientific article published on 17 September 2015

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

scientific article published on 31 May 2016

Hibiscus sabdariffaextract lowers blood pressure and improves endothelial function

scientific article published on 24 February 2014

High-performance liquid chromatography with diode array detection coupled to electrospray time-of-flight and ion-trap tandem mass spectrometry to identify phenolic compounds from a Cistus ladanifer aqueous extract

scientific article published on 01 July 2010

Isolation, comprehensive characterization and antioxidant activities of Theobroma cacao extract

Laparoscopic sleeve gastrectomy reverses non-alcoholic fatty liver disease modulating oxidative stress and inflammation

scientific article published on 04 July 2019

Managing hypertension by polyphenols.

scientific article

Mapping of the circulating metabolome reveals α-ketoglutarate as a predictor of morbid obesity-associated non-alcoholic fatty liver disease

scientific article published on 28 March 2014

Metabolite normalization with local radiotherapy following breast tumor resection

scientific article published in PLoS ONE

Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation

scientific article published on 06 November 2018

Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study.

scientific article

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX

scientific article published on 08 May 2018

Metformin induces a fasting- and antifolate-mimicking modification of systemic host metabolism in breast cancer patients.

scientific article

Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism.

scientific article

Metformin targets histone acetylation in cancer-prone epithelial cells

scientific article published on 28 October 2016

Methotrexate selectively targets human proinflammatory macrophages through a thymidylate synthase/p53 axis.

scientific article

Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate

scientific article published on 13 June 2016

Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users.

scientific article published on 10 February 2017

Oncometabolic Nuclear Reprogramming of Cancer Stemness

scientific article published on 27 January 2016

Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype.

scientific article published on May 2015

Paraoxonases and chemokine (C-C motif) ligand-2 in noncommunicable diseases

scientific article published on January 2014

Phenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: extra virgin olive oil as a source of novel antiaging phytochemicals.

scientific article published on 9 January 2012

Pine bark and green tea concentrated extracts: antioxidant activity and comprehensive characterization of bioactive compounds by HPLC-ESI-QTOF-MS.

scientific article published on 6 November 2014

Plasma Energy-Balance Metabolites Discriminate Asymptomatic Patients with Peripheral Artery Disease

scientific article published on 20 September 2018

Plasma metabolic alterations in patients with severe obesity and non-alcoholic steatohepatitis

scientific article published on 11 December 2019

Polyphenols and the modulation of gene expression pathways: can we eat our way out of the danger of chronic disease?

scientific article

Progress in the Synthesis of Poly(2,7-Fluorene-alt-1,4-Phenylene), PFP, via Suzuki Coupling

Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways.

scientific article published on 24 July 2015

The acute impact of polyphenols from Hibiscus sabdariffa in metabolic homeostasis: an approach combining metabolomics and gene-expression analyses

scientific article published on 3 August 2015

The impact of polyphenols on chondrocyte growth and survival: a preliminary report

scientific article

Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents

scientific article