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List of works by Patrick N. Harter

"Two is not enough" - Impact of the number of tissue samples obtained from stereotactic brain biopsies in suspected glioblastoma

scientific article published on 24 October 2017

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

scientific article published on 01 November 2020

ATP synthase deficiency due to TMEM70 mutation leads to ultrastructural mitochondrial degeneration and is amenable to treatment

scientific article published on 13 October 2015

AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia

publication published on 08 June 2021

Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma

scientific article published on 21 August 2018

Analysis of cerebral angiogenesis in human glioblastomas.

scientific article

Angiopoietin-2 promotes myeloid cell infiltration in a β₂-integrin-dependent manner

scientific article published on 25 August 2011

Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.

scientific article

Assessment of molecular markers demonstrates concordance between samples acquired via stereotactic biopsy and open craniotomy in both anaplastic astrocytomas and glioblastomas

scientific article

Autophagy-associated proteins BAG3 and p62 in testicular cancer.

scientific article published on 22 December 2015

BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease

scientific article published on 13 October 2015

Benefit of tumor resection for recurrent glioblastoma.

scientific article

Bevacizumab and radiotherapy for the treatment of glioblastoma: brothers in arms or unholy alliance?

scientific article

Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine.

scientific article published on 25 May 2017

Bevacizumab for Patients with Recurrent Multifocal Glioblastomas

scientific article published on 20 November 2017

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

scientific article

Brain invasion in otherwise benign meningiomas does not predict tumor recurrence

scientific article published on 27 July 2016

Brain stem infarction associated with familial Mediterranean fever and central nervous system vasculitis

scientific article published on May 27, 2013

C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases

scientific article published on 3 March 2016

CASP9 germline mutation in a family with multiple brain tumors

scientific article

CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms

scientific article published on 25 March 2011

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas

scientific article published on 08 July 2020

Cardiac period 2 in myocardial ischemia: clinical implications of a light dependent protein

scientific article published on 03 January 2013

Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p

scientific article published on 31 October 2018

Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.

scientific article

DNA methylation-based classification of central nervous system tumours

scientific article published on 14 March 2018

Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease.

scientific article published on 2 October 2017

Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas

scientific article

Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation

scientific article published in October 2013

Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas

scientific article

Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy

scientific article

Disruption of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α reverts key features of the neoplastic phenotype of glioma cells

scientific article published on 21 December 2018

Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

scientific article published on 16 October 2015

Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy

scientific article published on 27 April 2016

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors

scientific article published on 01 September 2018

EGFL7 ligates αvβ3 integrin to enhance vessel formation

scientific article published on 5 February 2013

EGFR heterogeneity and implications for therapeutic intervention in glioblastoma

scientific article published on 10 October 2017

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

scientific article published on 10 June 2016

Elevated HLA-E levels in human glioblastomas but not in grade I to III astrocytomas correlate with infiltrating CD8+ cells.

scientific article

Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma

scientific article

ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma.

scientific article published on 6 December 2015

Expression of vascular endothelial growth factor (VEGF) and its receptors VEGFR1 and VEGFR2 in primary and recurrent WHO grade III meningiomas

scientific article published on March 11, 2013

FOXO3a orchestrates glioma cell responses to starvation conditions and promotes hypoxia-induced cell death

scientific article published on 4 November 2016

Fermented Mistletoe Extract as a Multimodal Antitumoral Agent in Gliomas ⬇️

scientific article published on October 22, 2012

Genetic and epigenetic characterization of posterior pituitary tumors

scientific article published on 18 October 2021

Gliosarcoma with bone infiltration and extracranial growth: case report and review of literature ⬇️

scientific article published on October 19, 2010

Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences

scientific article

Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid

scientific article

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen

scientific article

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors

scientific article published on 19 May 2015

Infratentorial IDH-mutant astrocytoma is a distinct subtype

scientific article published on 10 August 2020

Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma

scientific article published on 20 October 2020

Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity.

scientific article

Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence

scientific article published on 7 April 2018

MR perfusion in and around the contrast-enhancement of primary CNS lymphomas.

scientific article published on 22 May 2013

MYCN amplification drives an aggressive form of spinal ependymoma

scientific article published on 14 August 2019

Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death

scientific article

MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients

scientific article published on February 2013

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

scientific article published on 25 March 2016

Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases

scientific article published on 29 October 2013

Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.

scientific article

Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases

scientific article

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

scientific article

Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas

scientific article published in February 2015

Perfusion MRI in the Evaluation of Suspected Glioblastoma Recurrence.

scientific article

Perioperative cerebral ischemia promote infiltrative recurrence in glioblastoma.

scientific article

Problems and challenges in the diagnosis of vertical infection with human cytomegalovirus (CMV): lessons from two accidental cases.

scientific article published on August 2011

Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation

scientific article published on 2 August 2017

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

scientific article published on 05 August 2021

Spatio-temporal deleted in colorectal cancer (DCC) and netrin-1 expression in human foetal brain development.

scientific article

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

scientific article published on 09 July 2018

Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma

scientific article published on 27 November 2017

Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.

scientific article

Sustained focal antitumor activity of bevacizumab in recurrent glioblastoma

scientific article published on 13 June 2014

Symptomatic intraspinal oncocytic adrenocortical adenoma

scientific article published on 01 January 2009

TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma

scientific article published on 23 March 2021

Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

scientific article published on 04 February 2020

The Impact of Early Corticosteroid Pretreatment Before Initiation of Chemotherapy in Patients With Primary Central Nervous System Lymphoma

scientific article published on 01 August 2019

The angiogenic switch leads to a metabolic shift in human glioblastoma

scientific article published on 3 September 2016

The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury

scientific article

The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma

scientific article published on 12 February 2019

Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF

scientific article published on 09 October 2019

β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.

scientific article published on 3 February 2015

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