List of works - Francisco Javier Cubero

A compared study on the purification of fetal and adult rat hepatocyte suspensions by biomagnetic isolation techniques and flow cytometry analysis.

scientific article published on January 2001

Adiponectin accounts for gender differences in hepatocellular carcinoma incidence

scientific article published on 03 April 2019

Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame

scientific article published on 25 September 2017

Alcohol and liver fibrosis.

scientific article published on 22 April 2009

Alcoholic liver disease: Utility of animal models

scientific article published on 01 December 2018

Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism

scientific article

Bone marrow-derived c-jun N-terminal kinase-1 (JNK1) mediates liver regeneration.

scientific article published on 22 October 2014

Changes in cerebral hemodynamics in cirrhotic patients after liver transplantation

scientific article published on 01 December 2018

Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy.

scientific article

Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.

scientific article published on 18 December 2015

Disruption of the FasL/Fas axis protects against inflammation-derived tumorigenesis in chronic liver disease

scientific article published on 08 February 2019

Dissecting the molecular pathophysiology of drug-induced liver injury.

scientific article published in April 2018

Dual targeting of G9a and DNMT1 for the treatment of experimental cholangiocarcinoma

scientific article published on 22 November 2020

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease.

scientific article published on 11 November 2015

Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor alpha, reduced glutathione, and transforming growth factor beta-dependent mechanisms

scientific article published on December 2008

Expression of bilirubin UDP-glucuronosyltransferase (bUGT) throughout fetal development: intrasplenic transplantation into Gunn rats to correct enzymatic deficiency

scientific article published on 01 December 2001

Expression of microRNA-155 in inflammatory cells modulates liver injury

scientific article published on 8 February 2018

Extracellular matrix and liver disease

scientific article

Extracellular vesicles in liver disease and beyond

scientific article published on 01 October 2018

Functional response of hepatocytes transplanted into Gunn rats stimulated with thyroid hormone

scientific article published on 12 December 2006

Functional role of CCL5/RANTES for HCC progression during chronic liver disease.

scientific article published on 20 December 2016

Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH.

scientific article published on 6 June 2017

Guidelines and Considerations for Metabolic Tolerance Tests in Mice

scientific article published on 18 February 2020

Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury.

scientific article published on 27 August 2014

Hepatic overexpression of cAMP-responsive element modulator α induces a regulatory T-cell response in a murine model of chronic liver disease.

scientific article published on 29 September 2016

Hepatic proliferation in Gunn rats transplanted with hepatocytes: effect of retrorsine and tri-iodothyronine

scientific article published on June 2005

Hepatic tissue environment in NEMO-deficient mice critically regulates positive selection of donor cells after hepatocyte transplantation

scientific article

Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents

scientific article published on 6 May 2013

High Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries.

scientific article published on 3 August 2017

Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis

scientific article published on 23 August 2018

Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice.

scientific article published on 26 October 2017

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

scientific article published on 14 March 2019

JNK: a double-edged sword in tumorigenesis

scientific article published on 01 October 2011

Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis

scientific article published on 13 September 2013

Keeping the liver fit with TREM2 during hepatic carcinogenesis

scientific article published on 04 November 2020

Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury

scientific article published on 14 August 2017

Kupffer cells and alcoholic liver disease.

scientific article published on June 2006

Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model

scientific article

Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma

scientific article published on 16 April 2020

Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury.

scientific article published on 28 August 2011

Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis.

scientific article published on December 2016

Mechanisms of liver fibrosis associated with experimental Fasciola hepatica infection: roles of Fas2 proteinase and hepatic stellate cell activation.

scientific article published on 9 September 2010

NF-κB essential modifier is required for hepatocyte proliferation and the oval cell reaction after partial hepatectomy in mice.

scientific article

Neurofibromatosis type 2/Merlin: sharpening the myth of prometheus

scientific article published on 01 May 2011

Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis

scientific journal article

Oxidative stress modulates KLF6Full and its splice variants.

scientific article

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

scientific article published on 21 June 2020

Plasticity of adult hepatocytes and readjustment of cell fate: a novel dogma in liver disease

scientific article published on 18 March 2019

Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury

scientific article published on 11 December 2018

Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha.

scientific article

Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death?

scientific article published on 28 February 2020

Reply

Shutting off inflammation: A novel switch on hepatic stellate cells.

scientific article published on 26 February 2016

Staging NAFLD: Diagnostic and Therapeutic Value of TAM Signaling

scientific article published on 25 December 2019

Survival of allogeneic hepatocytes transplanted into the thymus

scientific article published on 21 February 2008

TAL deficiency, all roads lead to oxidative stress?

scientific article

TRAIL but not FasL and TNFα, regulates IL-33 expression in murine hepatocytes during acute hepatitis

scientific article published on 24 September 2012

The Lieber-DeCarli Diet-A Flagship Model for Experimental Alcoholic Liver Disease

scientific article published on 9 August 2018

Unfolded protein response is an early, non-critical event during hepatic stellate cell activation

scientific article published on 04 February 2019

c-Jun N-terminal kinase 2 promotes enterocyte survival and goblet cell differentiation in the inflamed intestine.

scientific article published on 18 January 2017

c-Jun NH(2)-terminal kinase 1 in hepatocytes: an essential mediator of insulin resistance

scientific article published on 01 June 2010

c-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease.

scientific article

p38γ is essential for cell cycle progression and liver tumorigenesis

scientific article published on 10 April 2019

List of works by Francisco Javier Cubero

A compared study on the purification of fetal and adult rat hepatocyte suspensions by biomagnetic isolation techniques and flow cytometry analysis.

Adiponectin accounts for gender differences in hepatocellular carcinoma incidence

Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame

Alcohol and liver fibrosis.

Alcoholic liver disease: Utility of animal models

Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism

Bone marrow-derived c-jun N-terminal kinase-1 (JNK1) mediates liver regeneration.

Changes in cerebral hemodynamics in cirrhotic patients after liver transplantation

Clinical scenarios for the use of S100β as a marker of hepatic encephalopathy.

Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.

Disruption of the FasL/Fas axis protects against inflammation-derived tumorigenesis in chronic liver disease

Dissecting the molecular pathophysiology of drug-induced liver injury.

Dual targeting of G9a and DNMT1 for the treatment of experimental cholangiocarcinoma

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease.

Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor alpha, reduced glutathione, and transforming growth factor beta-dependent mechanisms

Expression of bilirubin UDP-glucuronosyltransferase (bUGT) throughout fetal development: intrasplenic transplantation into Gunn rats to correct enzymatic deficiency

Expression of microRNA-155 in inflammatory cells modulates liver injury

Extracellular matrix and liver disease

Extracellular vesicles in liver disease and beyond

Functional response of hepatocytes transplanted into Gunn rats stimulated with thyroid hormone

Functional role of CCL5/RANTES for HCC progression during chronic liver disease.

Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH.

Guidelines and Considerations for Metabolic Tolerance Tests in Mice

Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury.

Hepatic overexpression of cAMP-responsive element modulator α induces a regulatory T-cell response in a murine model of chronic liver disease.

Hepatic proliferation in Gunn rats transplanted with hepatocytes: effect of retrorsine and tri-iodothyronine

Hepatic tissue environment in NEMO-deficient mice critically regulates positive selection of donor cells after hepatocyte transplantation

Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents

High Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries.

Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis

Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice.

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

JNK: a double-edged sword in tumorigenesis

Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis

Keeping the liver fit with TREM2 during hepatic carcinogenesis

Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury

Kupffer cells and alcoholic liver disease.

Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model

Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma

Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury.

Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis.

Mechanisms of liver fibrosis associated with experimental Fasciola hepatica infection: roles of Fas2 proteinase and hepatic stellate cell activation.

NF-κB essential modifier is required for hepatocyte proliferation and the oval cell reaction after partial hepatectomy in mice.

Neurofibromatosis type 2/Merlin: sharpening the myth of prometheus

Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis

Oxidative stress modulates KLF6Full and its splice variants.

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

Plasticity of adult hepatocytes and readjustment of cell fate: a novel dogma in liver disease

Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury

Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha.

Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death?

Reply

Shutting off inflammation: A novel switch on hepatic stellate cells.

Staging NAFLD: Diagnostic and Therapeutic Value of TAM Signaling

Survival of allogeneic hepatocytes transplanted into the thymus

TAL deficiency, all roads lead to oxidative stress?

TRAIL but not FasL and TNFα, regulates IL-33 expression in murine hepatocytes during acute hepatitis

The Lieber-DeCarli Diet-A Flagship Model for Experimental Alcoholic Liver Disease

Unfolded protein response is an early, non-critical event during hepatic stellate cell activation

c-Jun N-terminal kinase 2 promotes enterocyte survival and goblet cell differentiation in the inflamed intestine.

c-Jun NH(2)-terminal kinase 1 in hepatocytes: an essential mediator of insulin resistance

c-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease.

p38γ is essential for cell cycle progression and liver tumorigenesis