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List of works by Ross A. Dickins

A pipeline for the generation of shRNA transgenic mice

scientific article published on 02 February 2012

A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.

scientific article

A rapid and scalable system for studying gene function in mice using conditional RNA interference

scientific article published on April 2011

A transgenic mouse model to inducibly target prosurvival Bcl2 proteins with selective BH3 peptides in vivo

scientific article published on 12 March 2015

ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

scientific journal article

Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia

scientific article published on 6 February 2015

Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors

scientific article published on 30 May 2018

Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors

scientific article

Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.

scientific article published on 11 February 2017

Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence

scientific article

Drosophila Hfp negatively regulates dmyc and stg to inhibit cell proliferation

scientific article published in March 2004

Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia

scientific article

Functional identification of optimized RNAi triggers using a massively parallel sensor assay

scientific article

Generation and analysis of Siah2 mutant mice.

scientific article

Generation of an inducible mouse model to reversibly silence Stat3.

scientific article published on 7 February 2017

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene

scientific article published on 06 March 2017

Humanizing the Protease-Activated Receptor (PAR) Expression Profile in Mouse Platelets by Knocking PAR1 into the Par3 Locus Reveals PAR1 Expression Is Not Tolerated in Mouse Platelets.

scientific article

IL-10 controls cystatin C synthesis and blood concentration in response to inflammation through regulation of IFN regulatory factor 8 expression.

scientific article published on 7 February 2011

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia

scientific article published on 30 June 2016

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

scientific article published on 01 August 2019

Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo

scientific article published on 21 July 2014

MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia

scientific article

Metabolic gatekeeper function of B-lymphoid transcription factors

scientific article published on 13 February 2017

Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

scientific article published on 26 February 2013

Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities

scientific article published on 3 October 2013

Normal p53 function in primary cells deficient for Siah genes.

scientific article

Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia

scientific article published on 06 July 2021

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia

scientific article published on 02 March 2016

Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia

scientific article

Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2

article

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

scientific article

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.

scientific article published on 16 August 2017

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

scientific article

Senescence of activated stellate cells limits liver fibrosis

scientific article

Stage-specific control of early B cell development by the transcription factor Ikaros

scientific article published on 9 February 2014

The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.

scientific article

The genomic landscape of hypodiploid acute lymphoblastic leukemia

scientific article published on 20 January 2013

The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice

scientific journal article

Tissue-specific and reversible RNA interference in transgenic mice

scientific article

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

scientific article published on 02 January 2019

Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia.

scientific article published on May 2006

Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.

scientific article

edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens

scientific article

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