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List of works by Eyad Elkord

5T4 as a target for immunotherapy in renal cell carcinoma

scientific article published on 01 December 2009

5T4 oncofetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype ⬇️

scientific article published on January 23, 2012

Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma.

scientific article published on 27 September 2007

Bead-isolated human CD4+CD25+ T regulatory cells are anergic and significantly suppress proliferation of CD4+CD25- T responder cells

scientific article published on 03 April 2006

Blockade of PD-1, PD-L1, and TIM-3 Altered Distinct Immune- and Cancer-Related Signaling Pathways in the Transcriptome of Human Breast Cancer Explants

scientific article published on 25 June 2020

CD4+ T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25+ T cells

scientific article published on 15 November 2007

CD8 T-cell recognition of human 5T4 oncofetal antigen.

scientific article

Circulating regulatory T cells in endometrial cancer: a role for age and menopausal status.

scientific article

Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients.

scientific article published on 11 February 2016

Comment on “Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells” ⬇️

scientific article published on July 15, 2012

Comparison of Myeloid Cells in Circulation and in the Tumor Microenvironment of Patients with Colorectal and Breast Cancers

scientific article published on 5 November 2017

Correlation between CD8+ T cells specific for prostate-specific antigen and level of disease in patients with prostate cancer.

scientific article published on 3 February 2006

DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer.

scientific article

DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

article

DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR- myeloid cells, compared with HLA-DR+ antigen-presenting cells ⬇️

scientific article published on 18 May 2020

DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients

scientific article published on 10 November 2018

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

scientific article

Differential CTLs specific for prostate-specific antigen in healthy donors and patients with prostate cancer.

scientific article published on September 2005

Differential gene expression of tumor-infiltrating CD33+ myeloid cells in advanced- versus early-stage colorectal cancer

scientific article published on 30 September 2020

Differential gene expression of tumor-infiltrating CD4+ T cells in advanced versus early stage colorectal cancer and identification of a gene signature of poor prognosis

scientific article published on 30 September 2020

Differential gene expression of tumor-infiltrating CD8+ T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis

scientific article published on 01 September 2020

Downregulation of immunosuppressive environment in patients with chronic HBV hepatitis on maintained remission

scientific article published on 11 February 2015

Dual inhibition of STAT1 and STAT3 activation downregulates expression of PD-L1 in human breast cancer cells

scientific article published on 02 May 2018

Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine

scientific article published on 11 July 2020

Effect of pembrolizumab on CD4+ CD25+ , CD4+ LAP+ and CD4+ TIM-3+ T cell subsets

scientific article published on 17 February 2019

Epigenetic regulation of immune checkpoints and T cell exhaustion markers in tumor-infiltrating T cells of colorectal cancer patients

scientific article published on 10 November 2020

Exosomes: Biological Carriers and Promising Tools for Cancer Immunotherapy

scientific article published on 16 July 2020

Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs

scientific article published on 29 April 2011

Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

scientific article published on 11 May 2020

Frequency of human T regulatory cells in peripheral blood is significantly reduced by cryopreservation

scientific article published on 16 June 2009

Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival

scientific article published on 09 May 2007

Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios(+) and Helios(-) Cells Coexist within the Natural FOXP3(+) T Regulatory Cell Subset in Humans.

scientific article published on 8 July 2016

Helios expression in FoxP3(+) T regulatory cells

scientific article published on 25 July 2012

Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP.

scientific article

Human monocyte isolation methods influence cytokine production from in vitro generated dendritic cells

scientific article published in February 2005

Immune checkpoint inhibitors: recent progress and potential biomarkers

scientific article published on 13 December 2018

Immune evasion in cancer: Mechanistic basis and therapeutic strategies.

scientific article published on 25 March 2015

Immune evasion mechanisms in colorectal cancer liver metastasis patients vaccinated with TroVax (MVA-5T4).

scientific article published on 17 February 2009

Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-α versus IFN-α.

scientific article published on February 2015

Immunology and immunotherapy approaches for prostate cancer.

scientific article published on 10 April 2007

Immunotherapy for gastrointestinal cancer: current status and strategies for improving efficacy

scientific article published on 01 April 2008

In vitro effect of IL-2 in combination with pazopanib or sunitinib on lymphocytes function and apoptosis of RCC cells

scientific article

In-vitro effect of pembrolizumab on different T regulatory cell subsets.

scientific article

Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients

scientific article published on 08 December 2016

Increased levels of granulocytic myeloid-derived suppressor cells in peripheral blood and tumour tissue of pancreatic cancer patients

scientific article published on 29 January 2014

Modulation of lymphocyte regulation for cancer therapy: a phase II trial of tremelimumab in advanced gastric and esophageal adenocarcinoma.

scientific article published on 23 February 2010

Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages

scientific article published on 12 June 2020

Myeloid cells in circulation and tumor microenvironment of breast cancer patients

scientific article

Myeloid-derived suppressor cells in cancer: recent progress and prospects.

scientific article published on 25 June 2013

Neuropilin 1: function and therapeutic potential in cancer

scientific article

Novel IFNγ ELISPOT assay for detection of functional carcinoembryonic antigen-specific chimeric antigen receptor-redirected T cells

scientific article published in October 2011

Novel expression of Neuropilin 1 on human tumor-infiltrating lymphocytes in colorectal cancer liver metastases

scientific article published on 29 October 2014

Novel therapeutic strategies by regulatory T cells in allergy.

scientific article published on January 2008

PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer

scientific article published on 25 July 2019

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications

scientific article published on 21 February 2019

Pembrolizumab Interferes with the Differentiation of Human FOXP3+-Induced T Regulatory Cells, but Not with FOXP3 Stability, through Activation of mTOR

scientific article published on 04 December 2019

Phenotypic alterations, clinical impact and therapeutic potential of regulatory T cells in cancer

scientific article published on 24 March 2014

Regulatory T Cells in the Tumor Microenvironment and Cancer Progression: Role and Therapeutic Targeting

scientific article

Role of regulatory T cells in allergy: implications for therapeutic strategy.

scientific article published on December 2006

SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities

scientific article published on 05 August 2020

Salmonella-mediated tumor regression involves targeting of tumor myeloid suppressor cells causing a shift to M1-like phenotype and reduction in suppressive capacity

scientific article published on 26 March 2014

Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity ⬇️

scientific article published on May 30, 2012

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19

scientific article published on 29 October 2020

Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor-An Opportunity for Cancer Treatment

scientific article published on 20 December 2019

T cell responses and therapies against SARS-CoV-2 infection

scientific article published on 15 September 2020

T cell-based immunotherapy of metastatic renal cell carcinoma: modest success and future perspective.

scientific article published on 20 October 2009

T regulatory cells in cancer: recent advances and therapeutic potential ⬇️

scientific article published on November 1, 2010

T-Regulatory Cells in Health and Disease

article

Targeting TIM-3 in solid tumors: innovations in the preclinical and translational realm and therapeutic potential

scientific article published on 24 October 2020

Therapeutic prospects of targeting myeloid-derived suppressor cells and immune checkpoints in cancer

scientific article published on 22 April 2018

Thymus-Derived, Peripherally Derived, and in vitro-Induced T Regulatory Cells

scientific article published on 24 January 2014

Transcriptomic Analyses Revealed Systemic Alterations in Gene Expression in Circulation and Tumor Microenvironment of Colorectal Cancer Patients

scientific article published on 11 December 2019

Transcriptomic Profiling of Circulating HLA-DR- Myeloid Cells, Compared with HLA-DR+ Myeloid Antigen-presenting Cells

scientific article published on 29 July 2020

Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer

scientific article published on 15 January 2020

Treg-mediated acquired resistance to immune checkpoint inhibitors

scientific article published on 09 May 2019

Tremelimumab (anti-CTLA4) mediates immune responses mainly by direct activation of T effector cells rather than by affecting T regulatory cells

scientific article published on 5 November 2010

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