List of works - Sara R. Jones

A Single Amphetamine Infusion Reverses Deficits in Dopamine Nerve-Terminal Function Caused by a History of Cocaine Self-Administration

scientific article published on 18 February 2015

Adaptations of presynaptic dopamine terminals induced by psychostimulant self-administration.

scientific article

Adolescent Social Isolation as a Model of Heightened Vulnerability to Comorbid Alcoholism and Anxiety Disorders.

scientific article published on 07 May 2016

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

scientific journal article

Amphetamine Reverses Escalated Cocaine Intake via Restoration of Dopamine Transporter Conformation.

scientific article published on 24 November 2017

Amphetamine potency varies with dopamine uptake rate across striatal subregions

scientific article

Amphetamine self-administration attenuates dopamine D2 autoreceptor function.

scientific article

Application of microdialysis and voltammetry to assess dopamine functions in genetically altered mice: correlation with locomotor activity.

scientific article

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

scientific article

Biphasic mechanisms of amphetamine action at the dopamine terminal.

scientific article published on April 2014

Bone histomorphometric and biomechanical abnormalities in mice homozygous for deletion of the dopamine transporter gene

scientific article published on 01 January 2000

Brief intermittent cocaine self-administration and abstinence sensitizes cocaine effects on the dopamine transporter and increases drug seeking

scientific article published on 12 September 2014

Chronic ethanol exposure alters presynaptic dopamine function in the striatum of monkeys: a preliminary study

scientific article published in December 2003

Chronic ethanol exposure increases inhibition of optically targeted phasic dopamine release in the nucleus accumbens core and medial shell ex vivo

scientific article published on 20 September 2017

Chronic ethanol self-administration in macaques shifts dopamine feedback inhibition to predominantly D2 receptors in nucleus accumbens core

scientific article

Chronic intermittent ethanol exposure reduces presynaptic dopamine neurotransmission in the mouse nucleus accumbens.

scientific article

Chronic methylphenidate administration in mice produces depressive-like behaviors and altered responses to fluoxetine

scientific article published on 13 June 2012

Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala

scientific article published on 28 May 2015

Chronic social isolation stress during peri-adolescence alters presynaptic dopamine terminal dynamics via augmentation in accumbal dopamine availability

scientific article

Cocaine Potency at the Dopamine Transporter Tracks Discrete Motivational States During Cocaine Self-Administration

scientific article published on 31 January 2017

Cocaine Self-Administration Produces Long-Lasting Alterations in Dopamine Transporter Responses to Cocaine

scientific article published on July 2016

Cocaine self-administration disrupts mesolimbic dopamine circuit function and attenuates dopaminergic responsiveness to cocaine.

scientific article published on 2 June 2015

Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate

scientific article

Cocaine-insensitive dopamine transporters with intact substrate transport produced by self-administration.

scientific article

Conserved dorsal-ventral gradient of dopamine release and uptake rate in mice, rats and rhesus macaques

scientific article published on 20 July 2012

Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure

scientific article published on 01 January 2018

Demon voltammetry and analysis software: analysis of cocaine-induced alterations in dopamine signaling using multiple kinetic measures

scientific article

Development of dopamine neurotransmission and uptake inhibition in the caudate nucleus as measured by fast-cyclic voltammetry

scientific article

Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder

scientific article

Differential influence of dopamine transport rate on the potencies of cocaine, amphetamine, and methylphenidate

scientific article

Diphenylpyraline, a histamine H1 receptor antagonist, has psychostimulant properties

scientific article

Direct and indirect 5-HT receptor agonists produce gender-specific effects on locomotor and vertical activities in C57 BL/6J mice.

scientific article published on 19 August 2009

Dissociation of rewarding and dopamine transporter-mediated properties of amphetamine.

scholarly article

Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure

scientific article published on 27 July 2016

Dopamine D3 autoreceptor inhibition enhances cocaine potency at the dopamine transporter.

scientific article published on 9 July 2016

Dopamine neuronal transport kinetics and effects of amphetamine

scientific article published in December 1999

Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains

scientific article published on 11 June 2016

Dopamine transporter-dependent and -independent actions of trace amine beta-phenylethylamine.

scientific article published in October 2004

Dopamine transporters govern diurnal variation in extracellular dopamine tone.

scientific article

Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors

scientific article

Early-Life Social Isolation Stress Increases Kappa Opioid Receptor Responsiveness and Downregulates the Dopamine System

scientific article published on 10 February 2016

Effect of moderate ethanol dose on dopamine uptake in rat nucleus accumbens in vivo

scientific article

Effects of chronic alcohol exposure on dopamine uptake in rat nucleus accumbens and caudate putamen.

scientific article

Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala.

scientific article

Effects of early life stress on drinking and serotonin system activity in rhesus macaques: 5-hydroxyindoleacetic acid in cerebrospinal fluid predicts brain tissue levels

scientific article published on 24 March 2012

Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward

scientific article published on 15 March 2012

Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats

scientific article

Ethanol-induced hyperactivity is associated with hypodopaminergia in the 22-TNJ ENU-mutated mouse

scientific article published on September 2009

Examining the complex regulation and drug-induced plasticity of dopamine release and uptake using voltammetry in brain slices

scientific article published on 06 May 2013

Exocytotic release of dopamine in ventral tegmental area slices from C57BL/6 and dopamine transporter knockout mice

scientific article published on 9 August 2006

Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: differential effects of glucocorticoids

scientific article published on 01 May 1996

Extended access of cocaine self-administration results in tolerance to the dopamine-elevating and locomotor-stimulating effects of cocaine

scientific article published on 21 October 2013

Fast onset of dopamine uptake inhibition by intravenous cocaine

scientific article published in November 2004

Frequency-dependent effects of ethanol on dopamine release in the nucleus accumbens

scientific article

Functional and anatomical evidence for different dopamine dynamics in the core and shell of the nucleus accumbens in slices of rat brain

scientific article published in July 1996

Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase

scientific article (publication date: June 2002)

Greater ethanol inhibition of presynaptic dopamine release in C57BL/6J than DBA/2J mice: Role of nicotinic acetylcholine receptors.

scientific article

Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics

scientific article (publication date: 2013)

High fat diet augments amphetamine sensitization in mice: Role of feeding pattern, obesity, and dopamine terminal changes

scientific article published on 4 June 2016

High-Fat-Diet-Induced Deficits in Dopamine Terminal Function Are Reversed by Restoring Insulin Signaling

scientific article published on 14 December 2016

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

scientific article

Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration

scientific article

Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine

scientific article published on 2 August 2016

Identification and validation of midbrain Kcnq4 regulation of heavy alcohol consumption in rodents.

scientific article

Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function

scientific article published in January 1998

Increased breakpoints on a progressive ratio schedule reinforced by IV cocaine are associated with reduced locomotor activation and reduced dopamine efflux in nucleus accumbens shell in rats

scientific article published on 19 September 2007

Increased presynaptic regulation of dopamine neurotransmission in the nucleus accumbens core following chronic ethanol self-administration in female macaques

scientific article published on 19 February 2016

Intermittent cocaine self-administration produces sensitization of stimulant effects at the dopamine transporter.

scientific article published on 24 February 2014

Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

scientific article published in December 1997

Lack of cocaine effect on dopamine clearance in the core and shell of the nucleus accumbens of dopamine transporter knock-out mice.

scientific article

Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice.

scientific article published on 14 October 2005

Long term sertraline effects on neural structures in depressed and nondepressed adult female nonhuman primates

scientific article

Loss of autoreceptor functions in mice lacking the dopamine transporter

scientific article

Low and high affinity dopamine transporter inhibitors block dopamine uptake within 5 sec of intravenous injection ⬇️

scientific article published on March 21, 2011

Manganese accumulation in striatum of mice exposed to toxic doses is dependent upon a functional dopamine transporter.

scientific article published on November 2005

Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression

scientific article

Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations.

scientific article

Moderate Alcohol Exposure during the Rat Equivalent to the Third Trimester of Human Pregnancy Alters Regulation of GABAA Receptor-Mediated Synaptic Transmission by Dopamine in the Basolateral Amygdala.

scientific article

Modulation of striatal dopamine dynamics by cocaine self-administration and amphetamine treatment in female rats

scientific article published on 01 June 2019

Neurochemical characterization of the release and uptake of dopamine in ventral tegmental area and serotonin in substantia nigra of the mouse

scientific article

No role of the dopamine transporter in acute ethanol effects on striatal dopamine dynamics

scientific article published in September 2006

Optogenetic versus electrical stimulation of dopamine terminals in the nucleus accumbens reveals local modulation of presynaptic release.

scientific article

Organic cation transporter 3 and the dopamine transporter differentially regulate catecholamine uptake in the basolateral amygdala and nucleus accumbens

scientific article published on 29 July 2020

Paradoxical tolerance to cocaine after initial supersensitivity in drug-use-prone animals.

scientific article published on 03 June 2013

Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes

scientific article

Protein kinase C beta regulates the D₂-like dopamine autoreceptor.

scientific article

Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis

scientific article published on 01 May 1998

Real-time voltammetric detection of cocaine-induced dopamine changes in the striatum of freely moving mice

scientific article published on 12 October 2009

Reduced dopamine terminal function and insensitivity to cocaine following cocaine binge self-administration and deprivation.

scientific article published in August 2005

Regulation of Tyrosine Hydroxylase Expression and Phosphorylation in Dopamine Transporter-Deficient Mice.

scientific article published on 28 April 2016

Reinforcing Doses of Intravenous Cocaine Produce Only Modest Dopamine Uptake Inhibition

scientific article published on 12 December 2016

Role of serotonin in cocaine effects in mice with reduced dopamine transporter function

scholarly article

Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission

scientific article

Sensitized nucleus accumbens dopamine terminal responses to methylphenidate and dopamine transporter releasers after intermittent-access self-administration

scientific article

Sertraline inhibits increases in body fat and carbohydrate dysregulation in adult female cynomolgus monkeys.

scientific article published on 21 February 2016

Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum

scientific article

Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood.

scientific article published on November 2014

Stress-Induced Alterations of Norepinephrine Release in the Bed Nucleus of the Stria Terminalis of Mice

scientific article published on 28 September 2018

Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens.

scientific article published on December 2015

Sustained N-methyl-d-aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling.

scientific article

Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors

scientific article published on 19 July 2016

Temporal pattern of cocaine intake determines tolerance vs sensitization of cocaine effects at the dopamine transporter.

scientific article published on 30 May 2013

The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration

scientific article

The dopamine transporter: a crucial component regulating dopamine transmission.

scientific article published on September 1997

The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system

scientific article

The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine

scientific article published on 25 June 2016

The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines.

scientific article published in November 2005

Voltammetric assessment of dopamine clearance in the absence of the dopamine transporter: no contribution of other transporters in core or shell of nucleus accumbens

scientific article published in December 2004

Voltammetric characterization of the effect of monoamine uptake inhibitors and releasers on dopamine and serotonin uptake in mouse caudate-putamen and substantia nigra slices.

scientific article

Voluntary ethanol intake predicts κ-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques

scientific article

Withdrawal from extended-access cocaine self-administration results in dysregulated functional activity and altered locomotor activity in rats

scientific article

α6β2 subunit containing nicotinic acetylcholine receptors exert opposing actions on rapid dopamine signaling in the nucleus accumbens of rats with high-versus low-response to novelty

scientific article

List of works by Sara R. Jones

A Single Amphetamine Infusion Reverses Deficits in Dopamine Nerve-Terminal Function Caused by a History of Cocaine Self-Administration

Adaptations of presynaptic dopamine terminals induced by psychostimulant self-administration.

Adolescent Social Isolation as a Model of Heightened Vulnerability to Comorbid Alcoholism and Anxiety Disorders.

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

Amphetamine Reverses Escalated Cocaine Intake via Restoration of Dopamine Transporter Conformation.

Amphetamine potency varies with dopamine uptake rate across striatal subregions

Amphetamine self-administration attenuates dopamine D2 autoreceptor function.

Application of microdialysis and voltammetry to assess dopamine functions in genetically altered mice: correlation with locomotor activity.

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

Biphasic mechanisms of amphetamine action at the dopamine terminal.

Bone histomorphometric and biomechanical abnormalities in mice homozygous for deletion of the dopamine transporter gene

Brief intermittent cocaine self-administration and abstinence sensitizes cocaine effects on the dopamine transporter and increases drug seeking

Chronic ethanol exposure alters presynaptic dopamine function in the striatum of monkeys: a preliminary study

Chronic ethanol exposure increases inhibition of optically targeted phasic dopamine release in the nucleus accumbens core and medial shell ex vivo

Chronic ethanol self-administration in macaques shifts dopamine feedback inhibition to predominantly D2 receptors in nucleus accumbens core

Chronic intermittent ethanol exposure reduces presynaptic dopamine neurotransmission in the mouse nucleus accumbens.

Chronic methylphenidate administration in mice produces depressive-like behaviors and altered responses to fluoxetine

Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala

Chronic social isolation stress during peri-adolescence alters presynaptic dopamine terminal dynamics via augmentation in accumbal dopamine availability

Cocaine Potency at the Dopamine Transporter Tracks Discrete Motivational States During Cocaine Self-Administration

Cocaine Self-Administration Produces Long-Lasting Alterations in Dopamine Transporter Responses to Cocaine

Cocaine self-administration disrupts mesolimbic dopamine circuit function and attenuates dopaminergic responsiveness to cocaine.

Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate

Cocaine-insensitive dopamine transporters with intact substrate transport produced by self-administration.

Conserved dorsal-ventral gradient of dopamine release and uptake rate in mice, rats and rhesus macaques

Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure

Demon voltammetry and analysis software: analysis of cocaine-induced alterations in dopamine signaling using multiple kinetic measures

Development of dopamine neurotransmission and uptake inhibition in the caudate nucleus as measured by fast-cyclic voltammetry

Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder

Differential influence of dopamine transport rate on the potencies of cocaine, amphetamine, and methylphenidate

Diphenylpyraline, a histamine H1 receptor antagonist, has psychostimulant properties

Direct and indirect 5-HT receptor agonists produce gender-specific effects on locomotor and vertical activities in C57 BL/6J mice.

Dissociation of rewarding and dopamine transporter-mediated properties of amphetamine.

Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure

Dopamine D3 autoreceptor inhibition enhances cocaine potency at the dopamine transporter.

Dopamine neuronal transport kinetics and effects of amphetamine

Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains

Dopamine transporter-dependent and -independent actions of trace amine beta-phenylethylamine.

Dopamine transporters govern diurnal variation in extracellular dopamine tone.

Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors

Early-Life Social Isolation Stress Increases Kappa Opioid Receptor Responsiveness and Downregulates the Dopamine System

Effect of moderate ethanol dose on dopamine uptake in rat nucleus accumbens in vivo

Effects of chronic alcohol exposure on dopamine uptake in rat nucleus accumbens and caudate putamen.

Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala.

Effects of early life stress on drinking and serotonin system activity in rhesus macaques: 5-hydroxyindoleacetic acid in cerebrospinal fluid predicts brain tissue levels

Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward

Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats

Ethanol-induced hyperactivity is associated with hypodopaminergia in the 22-TNJ ENU-mutated mouse

Examining the complex regulation and drug-induced plasticity of dopamine release and uptake using voltammetry in brain slices

Exocytotic release of dopamine in ventral tegmental area slices from C57BL/6 and dopamine transporter knockout mice

Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: differential effects of glucocorticoids

Extended access of cocaine self-administration results in tolerance to the dopamine-elevating and locomotor-stimulating effects of cocaine

Fast onset of dopamine uptake inhibition by intravenous cocaine

Frequency-dependent effects of ethanol on dopamine release in the nucleus accumbens

Functional and anatomical evidence for different dopamine dynamics in the core and shell of the nucleus accumbens in slices of rat brain

Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase

Greater ethanol inhibition of presynaptic dopamine release in C57BL/6J than DBA/2J mice: Role of nicotinic acetylcholine receptors.

Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics

High fat diet augments amphetamine sensitization in mice: Role of feeding pattern, obesity, and dopamine terminal changes

High-Fat-Diet-Induced Deficits in Dopamine Terminal Function Are Reversed by Restoring Insulin Signaling

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration

Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine

Identification and validation of midbrain Kcnq4 regulation of heavy alcohol consumption in rodents.

Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function

Increased breakpoints on a progressive ratio schedule reinforced by IV cocaine are associated with reduced locomotor activation and reduced dopamine efflux in nucleus accumbens shell in rats

Increased presynaptic regulation of dopamine neurotransmission in the nucleus accumbens core following chronic ethanol self-administration in female macaques

Intermittent cocaine self-administration produces sensitization of stimulant effects at the dopamine transporter.

Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

Lack of cocaine effect on dopamine clearance in the core and shell of the nucleus accumbens of dopamine transporter knock-out mice.

Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice.

Long term sertraline effects on neural structures in depressed and nondepressed adult female nonhuman primates

Loss of autoreceptor functions in mice lacking the dopamine transporter

Low and high affinity dopamine transporter inhibitors block dopamine uptake within 5 sec of intravenous injection ⬇️

Manganese accumulation in striatum of mice exposed to toxic doses is dependent upon a functional dopamine transporter.

Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression

Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations.

Moderate Alcohol Exposure during the Rat Equivalent to the Third Trimester of Human Pregnancy Alters Regulation of GABAA Receptor-Mediated Synaptic Transmission by Dopamine in the Basolateral Amygdala.

Modulation of striatal dopamine dynamics by cocaine self-administration and amphetamine treatment in female rats