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List of works by Tarik Issad

30 Years Old: O-GlcNAc Reaches the Age of Reason - Regulation of Cell Signaling and Metabolism by O-GlcNAcylation

scientific article published on 9 February 2015

A leptin missense mutation associated with hypogonadism and morbid obesity.

scientific article published in March 1998

A new highly efficient substrate-trapping mutant of protein tyrosine phosphatase 1B (PTP1B) reveals full autoactivation of the insulin receptor precursor

scientific article

Analysis of insulin receptor phosphorylation sites in intact rat liver cells by two-dimensional phosphopeptide mapping. Predominance of the tris-phosphorylated form of the kinase domain after stimulation by insulin.

scientific article published on April 1991

Cancer research: a privileged field of investigation on chance, reductionism and holism

scientific article

Development of a human breast-cancer derived cell line stably expressing a bioluminescence resonance energy transfer (BRET)-based phosphatidyl inositol-3 phosphate (PIP3) biosensor

scientific article

Development of insulin-sensitivity at weaning in the rat. Role of the nutritional transition.

scientific article published on May 1988

Effect of acarbose on glucose homeostasis, lipogenesis and lipogenic enzyme gene expression in adipose tissue of weaned rats.

scientific article published on June 1993

Effect of anesthesia on glucose production and utilization in rats

scientific article published in March 1987

Effect of dexamethasone on adipocyte differentiation markers and tumour necrosis factor-alpha expression in human PAZ6 cells.

scientific article

Effect of glucagon on insulin receptor phosphorylation in intact liver cells

scientific article published on January 13, 1992

Effect of insulin analogues on insulin/IGF1 hybrid receptors: increased activation by glargine but not by its metabolites M1 and M2

scientific article (publication date: 2012)

Effect of insulin analogues on phosphatidyl inositol-3 kinase/Akt signalling in INS-1 rat pancreatic derived β-cells

scientific article published on 26 December 2015

Effect of thiazolidinediones on expression of UCP2 and adipocyte markers in human PAZ6 adipocytes

scientific article published on May 1999

Effects of fasting on tissue glucose utilization in conscious resting rats. Major glucose-sparing effect in working muscles.

scientific article published on August 1987

Fibroblast growth factor-2 has opposite effects on human breast cancer MCF-7 cell growth depending on the activation level of the mitogen-activated protein kinase pathway

scientific article published on 01 November 1998

Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation

scientific article

Hijacking of the O-GlcNAcZYME complex by the HTLV-1 Tax oncoprotein facilitates viral transcription.

scientific article

Hypoxia increases leptin expression in human PAZ6 adipose cells.

scientific article

Identification of insulin-sensitizing molecules acting by disrupting the interaction between the Insulin Receptor and Grb14.

scientific article published on 4 December 2017

Increased mitogen-activated protein kinase expression and activity in white adipose tissue of ventromedial hypothalamus-lesioned rats.

scientific article published on May 1997

Insulin receptor function is preserved in a physiological state of hypoinsulinemia and insulin resistance

scientific article published on June 1, 1992

Insulin receptor substrates-5 and -6 are poor substrates for the insulin receptor.

scientific article

Insulin resistance during suckling period in rats

scientific article published on 01 August 1987

Isoproterenol inhibits insulin-stimulated tyrosine phosphorylation of the insulin receptor without increasing its serine/threonine phosphorylation

scientific article published on 01 November 1995

Lipopolysaccharide Induces GFAT2 Expression to Promote O-Linked β-N-Acetylglucosaminylation and Attenuate Inflammation in Macrophages

scientific article published on 25 September 2020

Molecular basis of insulin action

scientific article published on 01 December 1998

Neuroinflammation induced by amyloid β25-35 modifies mucin-type O-glycosylation in the rat's hippocampus

scientific article published on 21 November 2017

O-GlcNAc glycosylation and regulation of cell signaling

scientific article published on August 2010

O-GlcNAc modification, insulin signaling and diabetic complications.

scientific article

O-GlcNAcylation and Inflammation: A Vast Territory to Explore

scientific article

O-GlcNAcylation of FoxO1 in pancreatic β cells promotes Akt inhibition through an IGFBP1-mediated autocrine mechanism.

scientific article published on 30 October 2013

O-GlcNAcylation of connexin 40: a sweet connection between diabetes and endothelial cell dysfunction? Focus on "O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice"

scientific article published on 16 September 2015

O-GlcNAcylation-inducing treatments inhibit estrogen receptor α expression and confer resistance to 4-OH-tamoxifen in human breast cancer-derived MCF-7 cells.

scientific article published on 11 July 2013

O-GlcNAcylation: A New Cancer Hallmark?

scientific article published on 12 August 2013

PAZ6 cells constitute a representative model for human brown pre-adipocytes

scientific article

Positive regulation of insulin signaling by neuraminidase 1.

scientific article published on 21 March 2013

Protein tyrosine phosphatase-1B and T-cell protein tyrosine phosphatase regulate IGF-2-induced MCF-7 cell migration

scientific article

Rat uncoupling protein 2 (UCP2): expression in obese ventromedial hypothalamus (VMH)-lesioned animals

scientific article published on 01 November 1998

Regulatory O-GlcNAcylation sites on FoxO1 are yet to be identified

scientific article published on 2 May 2015

Sam68 interacts with IRS1.

scientific article

Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor

scientific article

Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human beta-3 adrenergic receptor: new pharmacological profile and mechanism of activation

scientific article published on 01 February 1999

Tau deletion promotes brain insulin resistance

scientific article

The involvement of leptin in humans revealed by mutations in leptin and leptin receptor genes

scientific article published on 01 June 1999

Two-dimensional phosphopeptide mapping of receptor tyrosine kinases

scientific article published on 01 January 2001

[Leptin and puberty in humans: hypothesis of the critical adipose mass revisited]

scientific article published on 01 September 1998

[Mechanisms of the intracellular effects of insulin]

scientific article published on 01 February 1995

[Protein O-GlcNAcylation and regulation of cell signalling: involvement in pathophysiology].

scientific article published on 8 September 2014

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