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List of works by Alexander Scheffold

Allergic sensitization and allergen exposure during pregnancy favor the development of atopy in the neonate

scientific article published on 01 January 2001

Antigen specificity and cross-reactivity drive functionally diverse anti–Aspergillus fumigatus T cell responses in cystic fibrosis

scientific article published in 2023

Antigen-reactive T cell enrichment for direct, high-resolution analysis of the human naive and memory Th cell repertoire

scientific article published on 11 March 2013

Antigen-specific cytometry--new tools arrived!

scientific article published on May 2004

Antigen-specific expansion of human regulatory T cells as a major tolerance mechanism against mucosal fungi.

scientific article

Antigen-specific regulatory T-cell responses against aeroantigens and their role in allergy

article

Author Correction: Antigen-specific regulatory T-cell responses against aeroantigens and their role in allergy

scientific article published on 01 May 2019

Autoregulation of Th1-mediated inflammation by twist1.

scientific article published on 28 July 2008

CD137+CD154- Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures.

scientific article published on 7 February 2018

CD14+CD34 low Cells With Stem Cell Phenotypic and Functional Features Are the Major Source of Circulating Endothelial Progenitors

scientific article published on 14 July 2005

Candida-Reactive T Cells for the Diagnosis of Invasive Candida Infection—A Prospective Pilot Study.

scientific article

Chemokine Transfer by Liver Sinusoidal Endothelial Cells Contributes to the Recruitment of CD4+ T Cells into the Murine Liver

scientific article published on 8 June 2015

Clinical-scale isolation of the total Aspergillus fumigatus-reactive T-helper cell repertoire for adoptive transfer

scientific article published on 15 July 2015

Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients.

scientific article published on August 2013

Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.

scientific article

Competition for cytokines: T(reg) cells take all

scientific article published on 01 December 2007

Critical Role of Preconceptional Immunization for Protective and Nonpathological Specific Immunity in Murine Neonates

scientific article published on October 1, 2003

Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis.

scientific article published on 11 December 2009

Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency.

scientific article published on 30 October 2005

Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

scientific article

Differential surrogate light chain expression governs B-cell differentiation

scientific article

Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

scientific article published on 31 May 2022

Exaggerated inflammatory response of primary human myeloid dendritic cells to lipopolysaccharide in patients with inflammatory bowel disease

scientific article

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

scientific article

Fine tuning and efficient T cell activation with stimulatory aCD3 nanoarrays.

scientific article published on 17 October 2013

Flow-cytometric analysis of rare antigen-specific T cells

scientific article published on 20 June 2013

Functional analysis of effector and regulatory T cells in a parasitic nematode infection

scientific article published on 3 March 2008

Fungus-Specific CD4 T Cells as Specific Sensors for Identification of Pulmonary Fungal Infections.

scientific article published on 22 November 2017

Fungus-specific CD4(+) T cells for rapid identification of invasive pulmonary mold infection.

scientific article

Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders

scientific article published on 26 October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

scholarly article

High-sensitivity immunofluorescence staining: a comparison of the liposome procedure and the FASER technique on mGR detection

scientific article

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus

scientific article

How alpha beta T cells deal with induced TCR alpha ablation

scientific article published on 10 July 2001

How can the latest technologies advance cell therapy manufacturing?

scientific article published on December 2014

Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans

scientific article published on 21 February 2019

Human CD4(+) T cells maintain specific functions even under conditions of extremely restricted ATP production

scientific article published in June 2008

Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction

scientific article published on 04 March 2008

IL-2 induces in vivo suppression by CD4(+)CD25(+)Foxp3(+) regulatory T cells.

scientific article published in June 2008

Identification and isolation of murine antigen-reactive T cells according to CD154 expression

scientific article published on September 2007

Identification of immunogenic antigens from Aspergillus fumigatus by direct multiparameter characterization of specific conventional and regulatory CD4+ T cells

scientific article published on 29 August 2014

Immune Responses to Broad-Spectrum Antibiotic Treatment and Fecal Microbiota Transplantation in Mice

scientific article

Immunoproteomics of Aspergillus for the development of biomarkers and immunotherapies

scientific article published on 17 June 2016

Impact of in utero Th2 immunity on T cell deviation and subsequent immediate-type hypersensitivity in the neonate

scientific article published on 01 February 2000

In-vitro-induced Th17 cells fail to induce inflammation in vivo and show an impaired migration into inflamed sites.

scientific article published in April 2010

Interleukin-2 is essential for CD4+CD25+ regulatory T cell function

scientific article

Liver sinusoidal endothelial cells induce immunosuppressive IL-10-producing Th1 cells via the Notch pathway

scientific article published on 12 May 2015

MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines

scientific article

Membrane glucocorticoid receptors (mGCR) on monocytes are up-regulated after vaccination

scientific article published on 18 December 2006

Membrane glucocorticoid receptors are down regulated by glucocorticoids in patients with systemic lupus erythematosus and use a caveolin-1-independent expression pathway

scientific article published on 31 January 2006

Mesenteric fat - control site for bacterial translocation in colitis?

scientific article published on 9 May 2012

Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo

scientific article published on 12 July 2005

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry

scientific article published on 28 June 2015

New technologies for monitoring human antigen-specific T cells and regulatory T cells by flow-cytometry

scientific article published on 22 May 2015

Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells.

scientific article published in August 2005

Notch regulates IL-10 production by T helper 1 cells

scholarly article

Nuclear antigen-reactive CD4+ T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys

scientific article published on 24 June 2020

Origin and functional activity of the membrane-bound glucocorticoid receptor

scientific article published in December 2011

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

scientific article published in Nature

Patients with active inflammatory bowel disease lack immature peripheral blood plasmacytoid and myeloid dendritic cells

scientific article

Prenatal sensitization in a mouse model

scientific article published on 01 September 2000

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus

article

Rapid detection, enrichment and propagation of specific T cell subsets based on cytokine secretion

scientific article published on October 21, 2010

Rapid glucocorticoid effects on immune cells

scientific article

Regulation of CD4+CD25+ regulatory T cell activity: it takes (IL-)two to tango

scientific article

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans

scientific article

Role of Blimp-1 in programing Th effector cells into IL-10 producers

scientific article published on 29 July 2014

Self-limitation of inflammatory T-cell responses. Help to self-help as a therapeutic concept

scientific article published in October 2008

Sensitive visualization of peptide presentation in vitro and ex vivo.

scientific article published in July 2003

Sequential production of IL-2, IFN-gamma and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes.

scientific article published in May 1998

Specific expression of surface interferon-gamma on interferon-gamma producing T cells from mouse and man

scientific article published on 01 January 1996

T-cell composition in ileal and colonic creeping fat - separating ileal from colonic Crohn´s disease

article

T-cell epitope mapping by flow cytometry

scientific article published on August 1, 1998

The Probiotic Compound VSL#3 Modulates Mucosal, Peripheral, and Systemic Immunity Following Murine Broad-Spectrum Antibiotic Treatment

scientific article

The effect of regulatory T cells on tolerance to airborne allergens and allergen immunotherapy

scientific article published on 01 December 2018

The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells

scientific article

Therapeutic manipulation of inflammation-promoting T cells: from suppression to self-control

scientific article published in September 2013

Timed action of IL-27 protects from immunopathology while preserving defense in influenza

scientific article

Towards in vivo application of RNA interference - new toys, old problems

scientific article

Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches-deficient mice.

scientific article published in May 2003

c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis

scientific article published on 18 February 2019

miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

scientific article published on 22 January 2015

siRNA stabilization prolongs gene knockdown in primary T lymphocytes.

scientific article