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List of works by Tom Mikkelsen

2D/3D image fusion for accurate target localization and evaluation of a mask based stereotactic system in fractionated stereotactic radiotherapy of cranial lesions

scientific article published in December 2006

A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence

scientific article published in April 2018

A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients

scientific article

A Nano-Sized PARAcest-Fluorescence Imaging Contrast Agent Facilitates and Validates In Vivo CEST MRI Detection of Glioma ⬇️

scientific article published on August 14, 2012

A Phase II Study of Dose-Dense Temozolomide and Lapatinib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma

scientific article published on 21 October 2020

A Phase II and Pharmacodynamic Trial of RO4929097 for Patients With Recurrent/Progressive Glioblastoma

scientific article published on 07 October 2020

A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting.

scientific article published on November 2004

A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma

scientific article

A phase I/II trial and pharmacokinetic study of ixabepilone in adult patients with recurrent high-grade gliomas

scientific article published on 07 May 2010

A phase I/II trial of pazopanib in combination with lapatinib in adult patients with relapsed malignant glioma.

scientific article published on 30 January 2013

A prognostic gene expression signature in infratentorial ependymoma

scientific article

A quantitative model of tumor-induced angiogenesis in the nude mouse

scientific article published in August 2005

AI-04MECHANISMS OF GLIOMA FORMATION: PERIVASCULAR GLIOMA INVASION IS A VEGF-INDEPENDENT MECHANISM OF TUMOR VASCULARIZATION

AT-07A PHASE II STUDY OF LAPATINIB AND DOSE-DENSE TEMOZOLOMIDE (TMZ) FOR ADULTS WITH RECURRENT EPENDYMOMA: PATIENT REPORTED OUTCOMES (PRO) FROM A CERN CLINICAL TRIAL.

scientific article published in November 2014

AT-23A PHASE II STUDY OF LAPATINIB AND DOSE-DENSE TEMOZOLOMIDE (TMZ) FOR ADULTS WITH RECURRENT EPENDYMOMA: A CERN CLINICAL TRIAL

AT-29INTRAVENOUS ADMINISTRATION OF TOCA 511 IN PATIENTS WITH RECURRENT GLIOBLASTOMA.

scientific article published in November 2014

ATIM-02. DURABLE RESPONSES OBSERVED IN IDH1 WILDTYPE AND MUTANT RECURRENT HIGH GRADE GLIOMA (rHGG) WITH TOCA 511 & TOCA FC TREATMENT

ATIM-21. INTRAVENOUS DELIVERY OF TOCA 511 IN PATIENTS WITH HIGH GRADE GLIOMA RESULTS IN QUANTIFIABLE EXPRESSION OF CYTOSINE DEAMINASE IN TUMOR TISSUE

ATIM-25. IMMUNOLOGICAL ACTIVATION IN RESPONDING PATIENTS WITH RECURRENT HGG AFTER TREATMENT WITH TOCA 511 & TOCA FC: RESULTS FROM A PHASE 1 TRIAL

ATIM-26. IMMUNOLOGIC TRENDS ASSOCIATED WITH PATIENT OUTCOMES IN A PHASE 1 CLINICAL TRIAL OF TOCA 511 AND TOCA FC IN RECURRENT HIGH GRADE GLIOMA

Abstract 1213: Comparing protein pathway activation mapping portraits between gliobastoma patient-matched primary tumor, xenografts and neurospheres: implications for precision medicine

Abstract 2061: Extended adjuvant temozolomide improves survival in a glioblastoma mouse model

Abstract 3385: Sox2 is necessary for glioblastoma cell plasticity

Abstract 3795: Cabozantinib affects multiple signaling pathways in glioblastoma and is effective in a subset of xenograft tumors

Abstract 3881:In vivo and in vitro characterization of genomic diversity and clonal evolution in glioblastoma

Abstract 4027: Regulation of p16INK4A and TGF-beta by DNA hydroxymethylation in glioblastoma multiforme

Abstract 4141: Tumor cell enrichment is critical for assessing cell signaling pathways in glioblastoma multiforme

Abstract 4155: The small leucine-rich proteoglycan biglycan localizes to the nucleus of neoplastic cells in glioblastoma biopsies and tumor xenografts

Abstract 427: Sox2 modulation of cancer stem cell behavior in GBM

Abstract 628: A method to examine spatial relationships between tumor cells and vasculature using a mouse orthotopic PDX glioblastoma model

Abstract A08: Neurosphere culture captures the clinical and molecular diversity of glioblastoma tumors

article

Abstract B55: Glioblastoma xenografts obtained from patient derived cancer stem cells preserve the heterogeneous response to targeted therapy

Addition of MR imaging features and genetic biomarkers strengthens glioblastoma survival prediction in TCGA patients

scientific article

An extended vascular model for less biased estimation of permeability parameters in DCE-T1 images.

scientific article published on 17 February 2017

An integrative approach for in silico glioma research

scientific article published on 23 July 2010

Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study

scientific article

Assessment of brain tumor angiogenesis inhibitors using perfusion magnetic resonance imaging: quality and analysis results of a phase I trial.

scientific article published in December 2004

Associations among magnetic resonance spectroscopy, apparent diffusion coefficients, and image-guided histopathology with special attention to radiation necrosis

scientific article published in May 2004

Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas ⬇️

scientific article published on February 1, 2012

BRAIN TUMOR CARE THROUGH THE PATIENT'S EYES — THE VALUE OF A COMPREHENSIVE BRAIN TUMOR CENTER.

scientific article published in July 2014

Bevacizumab and irinotecan treatment for progressive diffuse brainstem glioma: case report

scientific article published on 13 January 2009

Brain Malignancy Steering Committee clinical trials planning workshop: report from the Targeted Therapies Working Group

scientific article

CABOZANTINIB IS EFFECTIVE IN A SUBSET OF XENOGRAFT GBM TUMORS AND AFFECTS MULTIPLE SIGNALING PATHWAYS.

scientific article published in July 2014

CBIO-10. REVERSIBILITY OF GLIOMA STEM CELLS’ SPHERE FORMATION EXPLAINS THEIR IN VITRO BEHAVIOR AND IN VIVO TUMORIGENESIS POTENTIAL

CNS Cancer Models

CS-09RTVP-1 PROMOTES THE MESENCHYMAL TRANSFORMATION OF GLIOMA STEM CELLS VIA THE CXCR4 AND IL-6 PATHWAYS

CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study.

scientific article

Can permeability measurements add to blood volume measurements in differentiating tumefactive demyelinating lesions from high grade gliomas using perfusion CT?

scientific article published on 15 October 2009

Cerebellar tumors in pediatric patients: can they be differentiated using diffusion-weighted imaging?

scientific article published on 01 February 2007

Cilengitide-induced temporal variations in transvascular transfer parameters of tumor vasculature in a rat glioma model: identifying potential MRI biomarkers of acute effects

scientific article

Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme

scientific article published on 01 August 2008

Clinical course and progression-free survival of adult intracranial and spinal ependymoma patients

scientific article published on 13 August 2014

Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma

scientific article published on 9 March 2016

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

scientific article

Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

scientific article

Correlation of immunohistologic and perfusion vascular parameters with MR contrast enhancement using image-guided biopsy specimens in gliomas.

scientific article

Correlations between magnetic resonance spectroscopy and image-guided histopathology, with special attention to radiation necrosis

scientific article published in October 2002

DDEL-06PRELIMINARY SAFETY OF TOCA 511, A RETROVIRAL REPLICATING VECTOR, IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA ACROSS THREE SEPARATE PHASE 1 STUDIES.

scientific article

DDEL-08OVERALL SAFETY AND EFFICACY IN SUBJECTS WITH RECURRENT HGG TREATED ACROSS 2 TOCAGEN STUDIES - PROGNOSTIC FACTORS ASSOCIATED WITH SURVIVAL.

scientific article

DW-MRI as a biomarker to compare therapeutic outcomes in radiotherapy regimens incorporating temozolomide or gemcitabine in glioblastoma

scientific article (publication date: 2012)

Decrease of endogenous vascular endothelial growth factor may not affect glioma cell proliferation and invasion.

scientific article published on January 2007

Developing a brain tumor center

scientific article

Development of a novel animal model to differentiate radiation necrosis from tumor recurrence.

scientific article published on 10 March 2012

Differentiating treatment-induced necrosis from recurrent/progressive brain tumor using nonmodel-based semiquantitative indices derived from dynamic contrast-enhanced T1-weighted MR perfusion.

scientific article

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

scientific article published on 23 April 2018

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons

scientific article published on 12 August 2013

Durable Complete Responses in Some Recurrent High Grade Glioma Patients Treated with Toca 511 & Toca FC.

scientific article

ET-12PHASE II STUDY OF ONARTUZUMAB PLUS BEVACIZUMAB VERSUS PLACEBO PLUS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA.

scientific article published in November 2014

Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study.

scientific article published on 26 October 2017

Erratum to: Development of a novel animal model to differentiate radiation necrosis from tumor recurrence

article

Exploring Predictors of Response to Dacomitinib in EGFR-Amplified Recurrent Glioblastoma

scientific article published on 08 June 2020

First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

scientific article

First-pass perfusion computed tomography: initial experience in differentiating recurrent brain tumors from radiation effects and radiation necrosis

scientific article published on 01 October 2007

GE-14TRANSCRIPTOMICPLASTICITYIS ASSOCIATED WITH THE TUMOR MICROENVIRONMENT IN GLIOBLASTOMA

scientific article published in November 2014

GE-17ALTERATION OF THE p53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA.

scientific article published in November 2014

GENE-23. DISCORDANT INHERITANCE OF CHROMOSOMAL AND EXTRACHROMOSOMAL DNA ELEMENTS CONTRIBUTE TO DYNAMIC DISEASE EVOLUTION IN GLIOBLASTOMA

GENO-12CLONAL EVOLUTION AND GENOMIC DIVERSITY IN A PANEL GLIOBLASTOMA TUMORS, NEUROSPHERE CULTURES AND ORTHOTOPIC XENOGRAFTS.

scientific article published on 9 November 2015

GENO-30DISTINCT GENE EXPRESSION PROFILE THAT IS NOT A KNOWN SURVIVAL PREDICTOR IN TUMORS FROM LONG-TERM HIGH GRADE GLIOMA SURVIVORS TREATED WITH A RETROVIRAL REPLICATING VECTOR ENCODING YEAST CYTOSINE DEAMINASE.

scientific article

Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas

scientific article published on 9 January 2008

Genomic mapping and survival prediction in glioblastoma: molecular subclassification strengthened by hemodynamic imaging biomarkers

scientific article

Glioblastoma cell enrichment is critical for analysis of phosphorylated drug targets and proteomic-genomic correlations

scientific article

Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo

scientific article published on February 2010

High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma

scientific article

High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances

scientific article

Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous system

scientific article published on 28 March 2013

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

scientific article published in October 2012

IMCT-05COMBINABILITY OF TOCA FC AND TOCA 511 WITH CHEMOTHERAPY AND TARGETED AGENTS.

scientific article

Imaging response criteria for recurrent gliomas treated with bevacizumab: role of diffusion weighted imaging as an imaging biomarker

scientific article published on 27 October 2009

Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM).

scientific article

Initial experience with bevacizumab treatment for biopsy confirmed cerebral radiation necrosis.

scientific article

Integrated morphologic analysis for the identification and characterization of disease subtypes

scientific article published on 24 January 2012

Intratumor distribution and test-retest comparisons of physiological parameters quantified by dynamic contrast-enhanced MRI in rat U251 glioma

scientific article

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

scientific article published on 8 February 2012

Key determinants of short-term and long-term glioblastoma survival: a 14-year retrospective study of patients from the Hermelin Brain Tumor Center at Henry Ford Hospital.

scientific article

MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set.

scientific article

MTR-19A MACROPHAGE-/MICROGLIAL-RICH TUMOR MICROENVIRONMENT MIMICS PRONEURAL TO MESENCHYMAL TRANSITION IN GLIOBLASTOMA.

scientific article

Machine-based morphologic analysis of glioblastoma using whole-slide pathology images uncovers clinically relevant molecular correlates

scientific article

Mechanisms of glioma formation: iterative perivascular glioma growth and invasion leads to tumor progression, VEGF-independent vascularization, and resistance to antiangiogenic therapy.

scientific article

MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1 ⬇️

scientific article published on May 1, 2013

Model selection for DCE‐T1 studies in glioblastoma ⬇️

scientific article published on November 29, 2011

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

scientific article published on January 2016

Morphologic MRI features, diffusion tensor imaging and radiation dosimetric analysis to differentiate pseudo-progression from early tumor progression ⬇️

scientific article published on February 18, 2013

NABTT 0502: a phase II and pharmacokinetic study of erlotinib and sorafenib for patients with progressive or recurrent glioblastoma multiforme.

scientific article published on 17 January 2013

NIMG-50SURVIVAL RATE PREDICTION IN PATIENTS WITH GLIOBLASTOMA MULTIFORME (GBM), USING DYNAMIC CONTRAST ENHANCED MRI AND NESTED MODEL SELECTION TECHNIQUE (NMS).

scientific article published on 9 November 2015

NIMG-52DYNAMIC CONTRAST ENHANCED MR ESTIMATION OF PHARMACOKINETIC PARAMETERS OF GLIOBLASTOMA MULTIFORME TUMORS: A COMPARISON STUDY FOR PERITUMORAL AND GLOBAL ARTERIAL INPUT FUNCTIONS USING MODEL SELECTION TECHNIQUE.

scientific article

NIMG-53A FUZZY-BASED MODEL TO PREDICT THE SURVIVAL RATE OF PATIENTS WITH GIOBLASTOMA MLTIFORME TUMOR.

scientific article

Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain

scientific article

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Odyssey of hope: a physician's guide to communicating with brain tumor patients across the continuum of care

scientific article published on 09 April 2009

Optimization of Glioblastoma Mouse Orthotopic Xenograft Models for Translational Research

scientific article

Optimization of high grade glioma cell culture from surgical specimens for use in clinically relevant animal models and 3D immunochemistry

scientific article published on 7 January 2014

Outcome prediction in patients with glioblastoma by using imaging, clinical, and genomic biomarkers: focus on the nonenhancing component of the tumor

scientific article

Overview of Molecular Signal Transduction of Malignant Gliomas and Correlation with Responses to Targeted Therapy Recent advances in Molecular Characterization of Glioblastoma

Overview of Molecular Signal Transduction of Malignant Gliomas and Correlation with Responses to Targeted Therapy Recent advances in Molecular Characterization of Glioblastoma

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery

scientific article published on 28 January 2020

Patterns of failure after radiosurgery to two different target volumes of enhancing lesions with and without FLAIR abnormalities in recurrent glioblastoma multiforme

scientific article

Peritumoral tissue compression is predictive of exudate flux in a rat model of cerebral tumor: an MRI study in an embedded tumor

scientific article

Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma

scientific article

Phase 2 study of CT-322, a targeted biologic inhibitor of VEGFR-2 based on a domain of human fibronectin, in recurrent glioblastoma

scientific article

Phase 2 study of weekly irinotecan in adults with recurrent malignant glioma: final report of NABTT 97-11.

scientific article published on January 2004

Phase 2 trial of copper depletion and penicillamine as antiangiogenesis therapy of glioblastoma

scientific article published on July 2005

Phase I Study of GRN1005 in Recurrent Malignant Glioma ⬇️

scientific article published on January 24, 2013

Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma.

scientific article

Phase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomas

scientific article

Phase I safety study of escalating doses of atrasentan in adults with recurrent malignant glioma

scientific article published on 13 May 2008

Phase I study of iniparib concurrent with monthly or continuous temozolomide dosing schedules in patients with newly diagnosed malignant gliomas.

scientific article published on 19 August 2015

Phase I study of terameprocol in patients with recurrent high-grade glioma

scientific article published on 8 February 2012

Phase I/II dose escalation trial of concurrent temozolomide and whole brain radiation therapy for multiple brain metastasis

scientific article published on 30 April 2010

Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma

scientific article published on 21 August 2018

Phase II clinical and pharmacologic study of radiation therapy and carboxyamido-triazole (CAI) in adults with newly diagnosed glioblastoma multiforme

scientific article

Phase II preradiation R115777 (tipifarnib) in newly diagnosed GBM with residual enhancing disease

scientific article published on 25 August 2008

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy

scientific article published on 14 August 2017

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy

scientific article published on 3 October 2017

Phase II trial of sunitinib as adjuvant therapy after stereotactic radiosurgery in patients with 1-3 newly diagnosed brain metastases

scientific article published on 6 August 2015

Phase III randomized trial comparing the efficacy of cediranib as monotherapy, and in combination with lomustine, versus lomustine alone in patients with recurrent glioblastoma

scientific article

Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy

scientific article

Predicting survival in glioblastomas using diffusion tensor imaging metrics.

scientific article

Prediction of Glioblastoma Multiform Response to Bevacizumab Treatment Using Multi-Parametric MRI ⬇️

scientific article published on January 11, 2012

RARE-24. OBJECTIVE RESPONSE AND CLINICAL BENEFIT IN RECURRENT EPENDYMOMA IN ADULTS: FINAL REPORT OF CERN 08-02: A PHASE II STUDY OF DOSE-DENSE TEMOZOLOMIDE AND LAPATINIB

RTHP-06. RANDOMIZED PROSPECTIVE TRIAL OF STEREOTACTIC RADIOSURGERY VERSUS CHEMOTHERAPY FOR RECURRENT MALIGNANT GLIOMA AFTER SECOND-LINE CHEMOTHERAPY

Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme

scientific article

Randomized prospective trial of fractionated stereotactic radiosurgery with chemotherapy versus chemotherapy alone for bevacizumab-resistant high-grade glioma

scientific article published on 22 May 2020

Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O6-Methylguanine-DNA

scientific article

Rebound tumour progression after the cessation of bevacizumab therapy in patients with recurrent high-grade glioma

scientific article published on 12 February 2010

Reproducibility and relative stability in magnetic resonance imaging indices of tumor vascular physiology over a period of 24h in a rat 9L gliosarcoma model

scientific article published on 5 September 2017

SCDT-06. QUANTIFIABLE LEVELS OF THE TRANSGENE, CYTOSINE DEAMINASE, IN TUMOR SAMPLES FOLLOWING INTRAVENOUS DELIVERY OF TOCA 511 IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA.

scientific article

SDF-1 and CXCR4 are up-regulated by VEGF and contribute to glioma cell invasion.

scientific article published on 20 June 2005

SURG-09RESULTS OF A DOSE ESCALATION TRIAL OF TOCA 511 WITH TOCA FC IN RECURRENT HGG UNDERGOING REPEAT RESECTION.

scientific article

Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.

scientific article

Salvage reirradiation for recurrent glioblastoma with radiosurgery: radiographic response and improved survival

scientific article published on 9 December 2008

Segmentation of corpus callosum using diffusion tensor imaging: validation in patients with glioblastoma.

scientific article

Sox2 promotes malignancy in glioblastoma by regulating plasticity and astrocytic differentiation

scientific article

Studying the heterogeneity of brain tumors using medium throughput LOH analysis ⬇️

scientific article published on January 1, 2002

Subcurative radiation significantly increases cell proliferation, invasion, and migration of primary glioblastoma multiforme in vivo

scientific article published on 09 September 2013

THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA.

scientific article published in July 2014

TMIC-22. DECIPHERING GLIOMA INTRINSIC TRANSCRIPTIONAL SUBTYPES IDENTIFIES TUMOR EVOLUTION ASSOCIATES WITH CHANGES IN IMMUNE-MICROENVIRONMENT

scientific article published on 6 November 2017

TMOD-36. GENE EXPRESSION ANALYSIS OF SHORT AND LONG SURVIVAL GROUPS OF GLIOBLASTOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS

article

Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial

scientific article published on 27 July 2009

Targeting integrins in malignant glioma

scientific article published on 04 September 2010

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Corpus Callosum Wallerian Degeneration in the Unilateral Brain Tumors: Evaluation with Diffusion Tensor Imaging (DTI) ⬇️

scientific article published on February 1, 2013

The Cyclin-like Protein Spy1 Regulates Growth and Division Characteristics of the CD133+ Population in Human Glioma

scientific article published on 01 January 2014

The Somatic Genomic Landscape of Glioblastoma

article

The effect of enzyme-inducing antiseizure drugs on the pharmacokinetics and tolerability of procarbazine hydrochloride.

scientific article published in September 2006

The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells.

scientific article published in August 2009

The integrated landscape of driver genomic alterations in glioblastoma

scientific article published on 05 August 2013

The role of salvage reirradiation for malignant gliomas that progress on bevacizumab

scientific article

The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation

scientific article published on 14 March 2014

The somatic genomic landscape of glioblastoma

scientific article

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis

scientific article published on 06 June 2016

Transforming fusions of FGFR and TACC genes in human glioblastoma

scientific article

Treatment induced necrosis versus recurrent/progressing brain tumor: going beyond the boundaries of conventional morphologic imaging.

scientific article published on 24 February 2010

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

scientific article published in July 2017

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

scientific article

Tumor vascular leakiness and blood volume estimates in oligodendrogliomas using perfusion CT: an analysis of perfusion parameters helping further characterize genetic subtypes as well as differentiate from astroglial tumors.

scientific article

Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class

scientific article published on 17 July 2013

Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study

scientific article published on 11 March 2015

Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group

scientific article published on 15 March 2010

Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma.

scientific article

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

scientific article

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