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List of works by Chiara Giacomelli

4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor

scientific article

A new D₂ dopamine receptor agonist allosterically modulates A(2A) adenosine receptor signalling by interacting with the A(2A)/D₂ receptor heteromer

scientific article published on 30 December 2011

Allosteric modulators of human A2B adenosine receptor

scientific article published on 19 December 2013

Antioxidant Activity of Compounds Isolated from Elaeagnus umbellata Promotes Human Gingival Fibroblast Well-Being

scientific article published on 07 February 2020

Apoptosis therapy in cancer: the first single-molecule co-activating p53 and the translocator protein in glioblastoma.

scientific article published on 23 April 2014

Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells

scientific article published on 3 April 2017

Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization.

scientific article published on 7 February 2017

Brain ageing and neurodegenerative disease: The role of cellular waste management

scientific article published on 28 October 2018

Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis.

scientific article published on 9 November 2017

Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity.

scientific article published on 23 November 2015

Cytokine secretion responsiveness of lymphomonocytes following cortisol cell exposure: Sex differences

scientific article published in PLoS ONE

Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides

scientific article published on 28 July 2015

Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.

scientific article published on 18 February 2011

Dual Inhibition of PDK1 and Aurora Kinase A: An Effective Strategy to Induce Differentiation and Apoptosis of Human Glioblastoma Multiforme Stem Cells.

scientific article published on 31 October 2016

Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer

scientific article published on 8 August 2017

Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects.

scientific article

Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists

scientific article published on 12 October 2014

Intracellular Bioinorganic Chemistry and Cross Talk Among Different -Omics

scientific article

Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death

scientific article

Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts

scientific article published on 28 January 2019

Microglial Pro-Inflammatory and Anti-Inflammatory Phenotypes Are Modulated by Translocator Protein Activation

scientific article published on 10 September 2019

Modulation of A2B adenosine receptor by 1-Benzyl-3-ketoindole derivatives

scientific article published on 8 September 2013

Molecular insight on the altered membrane trafficking of TrkA kinase dead mutants

scientific article published on 21 November 2019

Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: the use of natural compounds as modulatory agents.

scientific article

New insights into the anticancer activity of carnosol: p53 reactivation in the U87MG human glioblastoma cell line

scientific article published on 29 February 2016

Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes

scientific article published on 01 November 2018

Novel positive allosteric modulators of A<sub>2B</sub> adenosine receptor acting as bone mineralisation promoters

scientific article published on 01 December 2021

Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators

scientific article published on 18 September 2014

Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals

scientific article

Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases

scientific article published on 31 January 2017

TSPO PIGA Ligands Promote Neurosteroidogenesis and Human Astrocyte Well-Being

scientific article published on 29 June 2016

TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance.

scientific article

TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy

scientific article published on 11 January 2016

Targeting the 18-kDa translocator protein: recent perspectives for neuroprotection

scientific article published on 03 August 2015

The A2B Adenosine Receptor Modulates the Epithelial- Mesenchymal Transition through the Balance of cAMP/PKA and MAPK/ERK Pathway Activation in Human Epithelial Lung Cells

scientific article published on 31 January 2018

The Ionophoric Activity of a Pro-Apoptotic VEGF165 Fragment on HUVEC Cells

scientific article published on 20 April 2020

Toward PET imaging of A2B adenosine receptors: a carbon-11 labeled triazinobenzimidazole tracer: Synthesis and imaging of a new A2B PET tracer.

scientific article published on 27 February 2016

p53 functional inhibitors behaving like pifithrin-β counteract the Alzheimer peptide non-β-amyloid component effects in human SH-SY5Y cells

scientific article published on 28 March 2014

α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise.

scientific article published on 30 January 2018

α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity.

scientific article published on 22 February 2018

♦Copper (II) ions modulate Angiogenin activity in human endothelial cells.

scientific article published on 14 January 2015

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