List of works by Ilkka Seppälä

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

scientific article published on 18 June 2015

A genome-wide association meta-analysis on apolipoprotein A-IV concentrations

scientific article published on 12 July 2016

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms

scientific article published on 16 May 2017

A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure

scientific article published on 27 March 2015

A meta-analysis of genome-wide association studies identifies multiple longevity genes

scientific article published on 14 August 2019

Activated immune-inflammatory pathways are associated with long-standing depressive symptoms: Evidence from gene-set enrichment analyses in the Young Finns Study

scientific article

Acute parvovirus B19 infection causes nonspecificity frequently in Borrelia and less often in Salmonella and Campylobacter serology, posing a problem in diagnosis of infectious arthropathy

scientific article published on 24 November 2010

Assessment of Imprecision in gamma interferon release assays for the detection of exposure to Mycobacterium tuberculosis

scientific article

Association of neuroimmune guidance cue netrin-1 and its chemorepulsive receptor UNC5B with atherosclerotic plaque expression signatures and stability in human(s): Tampere Vascular Study (TVS).

scientific article

Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke

scientific article published on 17 March 2016

Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism-The Young Finns Study

scientific article published on 05 December 2016

Blood pathway analyses reveal differences between prediabetic subjects with or without dyslipidaemia. The Cardiovascular Risk in Young Finns Study

scientific article published on 13 June 2017

Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study

scientific article

Childhood physical, environmental, and genetic predictors of adult hypertension: the cardiovascular risk in young Finns study

scientific article

Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts

scientific article

Complementary prediction of cardiovascular events by estimated apo- and lipoprotein concentrations in the working age population. The Health 2000 Study

scientific article published on 24 April 2012

Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians

scientific article

Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study

scientific article published on 27 January 2017

Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm - The Tampere Vascular Study

scientific article published on 21 September 2017

Expression and sequence diversity of the complement regulating outer surface protein E in Borrelia afzelii vs. Borrelia garinii in patients with erythema migrans or neuroborreliosis

scientific article published on 9 August 2010

Gene-environment correlations in parental emotional warmth and intolerance: genome-wide analysis over two generations of the Young Finns Study

article

Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--

scientific article

Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study

scientific article published on 24 October 2011

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Meta-Analysis of Sciatica in Finnish Population

scientific article

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

scientific article published on 13 December 2016

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality

scientific article

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

scientific article published on 13 October 2017

HLA-DRB1*01 allele and low plasma immunoglobulin G1 concentration may predispose to herpes-associated recurrent lymphocytic meningitis

scientific article

Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory

scientific article published on 15 May 2014

Higher maternal body mass index is associated with an increased risk for later type 2 diabetes in offspring

scientific article

IGRA tests perform similarly to TST but cause no adverse reactions: pediatric experience in Finland

scientific article

Identification of a Genetic Variation in ERAP1 Aminopeptidase that Prevents Human Cytomegalovirus miR-UL112-5p-Mediated Immunoevasion

scientific article

Immunosuppression Adversely Affects TST but Not IGRAs in Patients with Psoriasis or Inflammatory Musculoskeletal Diseases

scientific article

Integrative approaches for large-scale transcriptome-wide association studies

scientific article published on 8 February 2016

Interleukin-6 and microRNA profiles induced by oral bacteria in human atheroma derived and healthy smooth muscle cells

scientific article

Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds

scientific article published on 13 July 2015

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Lyme borreliosis and facial paralysis--a prospective analysis of risk factors and outcome

scientific article published on May 2002

Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts

scientific article

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

scientific article published on 11 September 2015

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

scientific article

Multi-ethnic genome-wide association study for atrial fibrillation

article

Pilot study of diagnostic potential of the Mycobacterium tuberculosis recombinant HBHA protein in a vaccinated population in Finland

scientific article

Plasma Concentrations of Afamin Are Associated With Prevalent and Incident Type 2 Diabetes: A Pooled Analysis in More Than 20,000 Individuals

scientific article published on 6 September 2017

Predicting sudden cardiac death using common genetic risk variants for coronary artery disease

scientific article published on 23 April 2015

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses

scientific article

Recombinant BBK32 protein in serodiagnosis of early and late Lyme borreliosis

scientific article

Species-specific serodiagnosis of Lyme arthritis and neuroborreliosis due to Borrelia burgdorferi sensu stricto, B. afzelii, and B. garinii by using decorin binding protein A.

scientific article

Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis

scientific article published on 2 November 2017

Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study

scientific article

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

scientific article published on 22 October 2015

The biomarker and causal roles of homoarginine in the development of cardiometabolic diseases: an observational and Mendelian randomization analysis

scientific article

The role of oxytocinergic genes in the intergenerational transmission of parent-child relationship qualities

scientific article published on 20 July 2019

Three genetic-environmental networks for human personality

scientific article published on 21 November 2019

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

scientific article

Uncovering the complex genetics of human character

article

Uncovering the complex genetics of human temperament

article

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Update on current care guidelines. Depressive disorder

scientific article published in January 2005

Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque

scientific article published on 11 April 2014

Varicella zoster and Borrelia burgdorferi are the main agents associated with facial paresis, especially in children

scientific article published on July 2003

Vascular cell adhesion molecule 1, soluble Fas and hepatocyte growth factor as predictors of mortality in nonagenarians: the Vitality 90+ study

scientific article published on 30 July 2013

Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes.

scientific article published on 20 June 2019

Widespread unilateral pain associated with herpes simplex virus infections

scientific article published on 15 April 2008