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List of works by Ulrich Kalinke

5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

scientific article

A CpG-rich bidirectional promoter induces the T-cell death-associated gene 51 and downregulates an inversely oriented transcript during early T-cell activation

scientific article

A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform.

scientific article

A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects

scientific article published on 11 January 2017

A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry.

scientific article published on 22 February 2017

A Soluble Version of Nipah Virus Glycoprotein G Delivered by Vaccinia Virus MVA Activates Specific CD8 and CD4 T Cells in Mice

scientific article published on 24 December 2019

A crucial role for B cells in neuroinvasive scrapie.

scientific article published in December 1997

A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance

scientific article

A fusion protein of flagellin and ovalbumin suppresses the TH2 response and prevents murine intestinal allergy.

scientific article

A highly conserved sequence of the viral TAP inhibitor ICP47 is required for freezing of the peptide transport cycle

scientific article

Abortively Infected Astrocytes Appear To Represent the Main Source of Interferon Beta in the Virus-Infected Brain

scientific article published on 9 December 2015

Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells

scientific article published on 24 July 2020

Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment

scientific article published on 2 November 2009

Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus.

scientific article published in May 2009

Additive effect of neutralizing antibody and antiviral drug treatment in preventing virus escape and persistence

scientific article

Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells

scientific article published on 16 December 2015

Antigen presenting cell-selective drug delivery by glycan-decorated nanocarriers

scientific article

Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies

scientific article published on 20 October 2003

Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment

scientific article published on April 2016

CD28 superagonists: what makes the difference in humans?

scientific article

CD4(+) T cells in patients with chronic inflammatory rheumatic disorders show distinct levels of exhaustion

scientific article published on 2 June 2016

CD40 ligand-triggered human dendritic cells mount interleukin-23 responses that are further enhanced by danger signals

scientific article

CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion

scientific article published in April 2006

Cell contact-dependent priming and Fc interaction with CD32+ immune cells contribute to the TGN1412-triggered cytokine response

scientific article

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.

scientific article published on 18 November 2013

Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes

scientific article

Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.

scientific article published on April 2005

Combinatorial immunoglobulin light chain variability creates sufficient B cell diversity to mount protective antibody responses against pathogen infections

scientific article published in April 2003

Comparative Analysis of Transduced Primary Human Dendritic Cells Generated by the Use of Three Different Lentiviral Vector Systems

scientific article published on 01 March 2011

Concomitant TLR/RLH signaling of radioresistant and radiosensitive cells is essential for protection against vesicular stomatitis virus infection

scientific article published on 15 August 2014

Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion

scientific article published in October 2010

Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance

scientific article published on October 2012

Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection

scientific article (publication date: 2012)

Corrigendum to “MHV-68 producing mIFNα1 is severely attenuated in vivo and effectively protects mice against challenge with wt MHV-68” [Vaccine 29 (2011) 3935–3944]

scholarly article published in Vaccine

Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox

scientific article (publication date: 2012)

Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN.

scientific article published in February 2006

Cytomegalovirus immune evasion of myeloid lineage cells

scientific article published on 17 March 2015

Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS.

scientific article published on 4 December 2011

Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL.

scientific article published on 20 July 2009

Differential Responses of Immune Cells to Type I Interferon Contribute to Host Resistance to Viral Infection

scientific article published in 2013

Differential Responses of Immune Cells to Type I Interferon Contribute to Host Resistance to Viral Infection

article

Direct Stimulation of T Cells by Type I IFN Enhances the CD8+ T Cell Response during Cross-Priming

scientific article published on 01 April 2006

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

Double-stranded RNA-binding protein E3 controls translation of viral intermediate RNA, marking an essential step in the life cycle of modified vaccinia virus Ankara

scientific article published in May 2006

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.

scientific article

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

scientific article

Effects of type I interferons on Friend retrovirus infection

scientific article published in April 2006

Efficient immune responses in mice lacking N-region diversity

article

Efficient virus assembly, but not infectivity, determines the magnitude of hepatitis C virus-induced interferon alpha responses of plasmacytoid dendritic cells

scientific article

Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17-mediated autoimmunity in the CNS.

scientific article

Enhancement of IFNγ Production by Distinct Commensals Ameliorates Salmonella-Induced Disease

scientific article published on June 2017

Excessive CpG 1668 stimulation triggers IL-10 production by cDC that inhibits IFN-α responses by pDC

article

Expression of the human cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-specific CD8 T cells

scientific article

Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis.

scientific article published on 28 October 2011

Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: role of macrophage scavenger receptor class A type I and II.

scientific article published on 27 October 2009

Growing tumors induce a local STING dependent Type I IFN response in dendritic cells

scientific article published on 26 April 2016

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

scientific article published on 12 December 2017

Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner

scientific article

Host strategies against virus entry via the olfactory system

scientific article published on July 2011

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

scientific article

ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation

scientific article published on 10 May 2012

IFIT2 Is an Effector Protein of Type I IFN-Mediated Amplification of Lipopolysaccharide (LPS)-Induced TNF- Secretion and LPS-Induced Endotoxin Shock

IFNalpha activates dormant haematopoietic stem cells in vivo.

scientific article published on 11 February 2009

IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs

scientific article published on 24 March 2014

Identification of a Predominantly Interferon-λ-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells.

scientific article published on 16 October 2017

Identification of a lysosomal peptide transport system induced during dendritic cell development

scientific article

Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation

scientific article published on 3 March 2014

Immune protection against reinfection with nonprimate hepacivirus.

scientific article published on 08 March 2017

Immunity against prions?

article

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages

scientific article

Impaired functionality of antiviral T cells in G-CSF mobilized stem cell donors: implications for the selection of CTL donor

scientific article

Independent of plasmacytoid dendritic cell (pDC) infection, pDC triggered by virus-infected cells mount enhanced type I IFN responses of different composition as opposed to pDC stimulated with free virus

scientific article published on 28 July 2014

Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation

scientific article

Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR

scientific article

Interferon regulatory factor-1 protects from fatal neurotropic infection with vesicular stomatitis virus by specific inhibition of viral replication in neurons

scientific article

Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice

scientific article published on 03 August 2018

Interferon-beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization.

scientific article

La Crosse Bunyavirus Nonstructural Protein NSs Serves To Suppress the Type I Interferon System of Mammalian Hosts

scientific article

Local type I IFN receptor signaling protects against virus spread within the central nervous system

scientific article published in February 2009

M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells

scientific article published on 17 September 2014

MHV-68 producing mIFNα1 is severely attenuated in vivo and effectively protects mice against challenge with wt MHV-68.

scientific article published on 8 April 2011

Macrophage depletion by liposome-encapsulated clodronate suppresses seizures but not hippocampal damage after acute viral encephalitis

scientific article

Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia

scientific article

Manufacturing and quality control of cell-based tumor vaccines: a scientific and a regulatory perspective

scientific article published on September 2006

Mathematical model of a virus-neutralizing immunglobulin response.

scientific article published in November 1998

Matrix protein mediated shutdown of host cell metabolism limits vesicular stomatitis virus-induced interferon-alpha responses to plasmacytoid dendritic cells

scientific article published on 9 November 2007

Mechanisms for interferon-α-induced depression and neural stem cell dysfunction.

scientific article

Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage

article

Modified vaccinia virus Ankara induces Toll-like receptor-independent type I interferon responses

scientific article published on 12 September 2007

Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation

scientific article published on 01 March 2019

Monovalent single-chain Fv fragments and bivalent miniantibodies bound to vesicular stomatitis virus protect against lethal infection.

scientific article published in December 1996

Morbillivirus control of the interferon response: relevance of STAT2 and mda5 but not STAT1 for canine distemper virus virulence in ferrets

scientific article published on 26 December 2013

Mycobacteria-induced granuloma necrosis depends on IRF-1.

scientific article

Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

scientific article published on 01 August 2010

N1L is an ectromelia virus virulence factor and essential for in vivo spread upon respiratory infection

scientific article

NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs.

scientific article

Nach dem TGN1412-Zwischenfall

scientific article published on 01 October 2007

Nanoparticle adjuvant sensing by TLR7 enhances CD8+ T cell-mediated protection from Listeria monocytogenes infection

scientific article published on 27 December 2013

Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection.

scientific article published on 7 November 2017

Ncf1 provides a reactive oxygen species-independent negative feedback regulation of TLR9-induced IL-12p70 in murine dendritic cells

scientific article published in April 2009

Neuroprotective effects of the cellular prion protein in autoimmune optic neuritis

scientific article

New lessons about old molecules: how type I interferons shape Th1/Th17-mediated autoimmunity in the CNS.

scientific article published on 28 June 2010

Non-tolerant B cells cause autoimmunity in anti-CD8 IgG2a-transgenic mice.

scientific article

Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus

scientific article published in September 2005

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway

scientific article published on 19 February 2020

Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes.

scientific article published on 21 December 2017

Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice

scientific article published on 29 June 2005

Poly(I:C)-Encapsulating Nanoparticles Enhance Innate Immune Responses to the Tuberculosis Vaccine Bacille Calmette-Guérin (BCG) via Synergistic Activation of Innate Immune Receptors

scientific article published on 3 October 2017

Postexposure immunization with modified vaccinia virus Ankara or conventional Lister vaccine provides solid protection in a murine model of human smallpox

scientific article

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies

scientific article published on 6 September 2001

Prion protein-specific antibodies for therapeutic intervention of transmissible spongiform encephalopathies

scientific article

Protection against RNA-induced liver damage by myeloid cells requires type I interferon and IL-1 receptor antagonist in mice

scientific article published on 28 February 2014

Protective role of beta interferon in host defense against influenza A virus

scientific article published on 6 December 2006

RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury

scientific article published on April 2017

Rapid expansion of CD8+ T cells in wild-type and type I interferon receptor-deficient mice correlates with protection after low-dose emergency immunization with modified vaccinia virus Ankara

scientific article

Regulation of antiviral T cell responses by type I interferons

scientific article published on 20 March 2015

Regulatory T-Cells Mediate IFN-α-Induced Resistance against Antigen-Induced Arthritis

scientific article published on 19 February 2018

Reply to: "Unveiling the depletion of Kupffer cells in experimental hepatocarcinogenesis through liver macrophage subtype-specific markers"

scientific article published on 18 June 2019

Reply to: “Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation”

scientific article published on 01 February 2019

Role of repetitive antigen patterns for induction of antibodies against antibodies

scientific article

STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus

scientific article published on 27 June 2019

Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses

scientific article

Selective gene transfer to T lymphocytes using coreceptor-specific [MLV(HIV)] pseudotype vectors in a transgenic mouse model

scientific article

Selective reconstitution of IFN‑γ gene function in Ncr1+ NK cells is sufficient to control systemic vaccinia virus infection

scientific article published on 05 February 2020

Short-term, but not post-exposure, protection against lethal orthopoxvirus challenge after immunization with modified vaccinia virus Ankara

scientific article published in October 2006

Signaling signatures and functional properties of anti-human CD28 superagonistic antibodies

scientific article (publication date: 2008)

Statins inhibit iNOS-mediated microbicidal potential of activated monocyte-derived dendritic cells by an IFN-β-dependent mechanism

scientific article

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

scientific article

Systemic Virus Infections Differentially Modulate Cell Cycle State and Functionality of Long-Term Hematopoietic Stem Cells In Vivo.

scientific article published on June 2017

Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity

scientific article

TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model

scientific article

TGN1412—a regulator's perspective

scientific article published on 01 May 2006

TLR-ligand stimulated interleukin-23 subunit expression and assembly is regulated differentially in murine plasmacytoid and myeloid dendritic cells.

scientific article published on 18 October 2006

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

scientific article

The European Regulatory Environment of RNA-Based Vaccines

scientific article published on January 2017

The antiviral drug ganciclovir does not inhibit microglial proliferation and activation

scientific article

The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13

scientific article published on 05 February 2020

The regulatory landscape for actively personalized cancer immunotherapies

article published in 2013

The role of antibody concentration and avidity in antiviral protection.

scientific article

The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus.

scientific article published in December 1996

The type I interferon response bridles rabies virus infection and reduces pathogenicity

scientific article

Thogoto virus infection induces sustained type I interferon responses that depend on RIG-I-like helicase signaling of conventional dendritic cells

scientific article published on 22 September 2010

Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice

Tolerogenic Transcriptional Signatures of Steady-State and Pathogen-Induced Dendritic Cells.

scientific article

Toward biosimilar monoclonal antibodies

scientific article published on 01 September 2008

Toward experimental assessment of receptor occupancy: TGN1412 revisited

Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway

scientific article

Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity

scientific article

Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection

scientific article

Type I Interferon Signaling Is Required for CpG-Oligodesoxynucleotide-Induced Control of Leishmania major, but Not for Spontaneous Cure of Subcutaneous Primary or Secondary L. major Infection

scientific article published on 5 February 2018

Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue.

scientific article

Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei

scientific article

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

scientific article

Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice

scientific article published on 17 June 2016

Type I interferon protects mice from fatal neurotropic infection with Langat virus by systemic and local antiviral responses.

scientific article published on 13 August 2014

Type I interferon receptor signaling delays Kupffer cell replenishment during acute fulminant viral hepatitis

scientific article published on 2 December 2017

Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells

scientific article published on 3 September 2009

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration.

scientific article

Type I interferon signals in macrophages and dendritic cells control dengue virus infection: implications for a new mouse model to test dengue vaccines

scientific article

Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia

scientific article published on 25 July 2006

Type I interferons protect T cells against NK cell attack mediated by the activating receptor NCR1.

scientific article published on 5 June 2014

Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets

scientific article published on 6 February 2015

Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon Beta producers that protect from lethal encephalitis

scientific article published on 24 December 2014

Vaccination with Abeta-displaying virus-like particles reduces soluble and insoluble cerebral Abeta and lowers plaque burden in APP transgenic mice

scientific article

Vaccinia virus-mediated inhibition of type I interferon responses is a multifactorial process involving the soluble type I interferon receptor B18 and intracellular components

scientific article published on 10 December 2008

Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration.

scientific article

Vesicular stomatitis virus glycoprotein displaying retrovirus-like particles induce a type I IFN receptor-dependent switch to neutralizing IgG antibodies

scientific article published in May 2007

Virally Infected Mouse Liver Endothelial Cells Trigger CD8+ T-Cell Immunity

Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo

scientific article published on February 2002

Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells

scientific article published on 21 January 2013

[Pulmonary Immune Mechanisms in Tuberculosis].

scientific article

cGAMP Quantification in Virus-Infected Human Monocyte-Derived Cells by HPLC-Coupled Tandem Mass Spectrometry

scientific article published on January 2017

cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

scientific article

cGAS-STING-TBK1-IRF3/7 induced interferon-β contributes to the clearing of non tuberculous mycobacterial infection in mice

scientific article published on 19 April 2017

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