List of works by Aroon Hingorani

(6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm

scientific article published on 05 April 2007

A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service

scientific article published on 20 May 2019

A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UK

scientific article published on 01 October 1999

A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium

scientific article

A gene-centric study of common carotid artery remodelling

scientific article published on 23 November 2012

A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering

scientific article published on 5 April 2016

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

scientific article

A simple molecular assay for the C1166 variant of the angiotensin II type 1 receptor gene

scientific article published on 01 August 1995

ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study

scientific article published on 23 October 2012

Addressing ethical challenges in the Genetics Substudy of the National Eye Survey of Trinidad and Tobago (GSNESTT).

scientific article published on 12 May 2016

Adiponectin and its association with bone mass accrual in childhood

scientific article

Adipose and height growth through childhood and blood pressure status in a large prospective cohort study

scientific article

Adiposity and cardiovascular risk factors in a large contemporary population of pre-pubertal children

scientific article

Adjustment for index event bias in genome-wide association studies of subsequent events

article

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

scientific article published in December 2016

Alcohol consumption and cognitive performance: a Mendelian randomization study

scientific article

Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction

scientific article published on 28 September 2010

Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: evidence of small-study bias

scientific article

Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals

scientific article

Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study

scientific article

Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery

scientific article

Association analyses based on false discovery rate implicate new loci for coronary artery disease ⬇️

scientific article published on 17 July 2017

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

scientific article (publication date: 15 February 2011)

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure

scientific article

Association between periodontal disease and its treatment, flow-mediated dilatation and carotid intima-media thickness: a systematic review and meta-analysis

scientific article published on 17 June 2014

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

scientific article published on 13 July 2020

Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes

scientific article published on 3 August 2016

Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies.

scientific article

Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood

scientific article

Association of pre-eclampsia risk with maternal levels of folate, homocysteine and vitamin B12 in Colombia: A case-control study

scientific article published in PLoS ONE

Association of the G(s)alpha gene with essential hypertension and response to beta-blockade

scientific article published on 01 July 1999

Association of the metabolic syndrome with severe periodontitis in a large U.S. population-based survey

scientific article published on 05 August 2008

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

scientific article

Associations of 25-hydroxyvitamin D2 and D3 with cardiovascular risk factors in childhood: cross-sectional findings from the Avon Longitudinal Study of Parents and Children

scientific article published on 16 February 2012

Associations of common genetic variants with age-related changes in fasting and postload glucose: evidence from 18 years of follow-up of the Whitehall II cohort

scientific article published on 25 March 2011

Associations of maternal 25-hydroxyvitamin D in pregnancy with offspring cardiovascular risk factors in childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children

scientific article published on 14 October 2013

Author Correction: Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance

scientific article published on 23 June 2020

Bayesian meta-analysis of genetic association studies with different sets of markers

scientific article published on April 2008

Bayesian test for colocalisation between pairs of genetic association studies using summary statistics

scientific article (publication date: May 2014)

Biological mechanisms of aging predict age-related disease co-occurrence in patients

scientific article published on 08 March 2022

Biomarkers of inflammation predict both vascular and non-vascular mortality in older men.

scientific article

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

scientific article

Blood pressure loci identified with a gene-centric array

scientific article

British Society for Rheumatology and British Health Professionals in Rheumatology Guideline for the Management of Gout

article

C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus

scientific article

C-reactive protein and coronary heart disease: predictive test or therapeutic target?

scientific article published on 29 December 2008

C-reactive protein and prognosis in diabetes: getting to the heart of the matter

scientific article published on April 2009

CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis

scientific article published on December 2011

CYP2D6 genotype and tamoxifen response for breast cancer: a systematic review and meta-analysis

scientific article

Cardiovascular biomarkers and vascular function during childhood in the offspring of mothers with hypertensive disorders of pregnancy: findings from the Avon Longitudinal Study of Parents and Children

scientific article published on 22 August 2011

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis

scientific article

Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis

scientific article

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

scientific article published on 28 December 2012

Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk

scientific article (publication date: 2012)

Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men.

scientific article published on 4 February 2008

Chronic inflammation, periodontitis and cardiovascular diseases

scientific article published on 01 March 2008

Circulating Apolipoprotein E Concentration and Cardiovascular Disease Risk: Meta-analysis of Results from Three Studies

scientific article

Clinical trial design and dissemination: comprehensive analysis of clinicaltrials.gov and PubMed data since 2005.

scientific article

Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs

scientific article

Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells.

scientific article published on October 2003

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

scientific article published on 30 July 2011

Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials

scientific article

Comparison of variance estimators for meta-analysis of instrumental variable estimates

scientific article

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype

scientific article published on 13 January 2012

Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.

scientific article published on 24 September 2013

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Could NICE guidance on the choice of blood pressure lowering drugs be simplified?

scientific article published on 13 January 2012

Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts

scientific article

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

scientific article

Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS.

scientific article published on March 1999

D-lactate encephalopathy.

scientific article published in November 2001

Data resource profile: cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER)

scientific article

Data-driven identification of ageing-related diseases from electronic health records

scientific article published on 3 February 2021

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Determinants of vascular phenotype in a large childhood population: the Avon Longitudinal Study of Parents and Children (ALSPAC).

scientific article

Diet, the endothelium and atherosclerosis

scientific article published on May 2004

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

scientific article published on 24 July 2017

Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay

scientific article

Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study

scientific article

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

scientific article

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

scientific article

Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis

scientific article

Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study

scientific article

Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia

scientific article published in May 2003

Endothelial nitric oxide in humans in health and disease.

scientific article

Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis

scientific article

Endothelial nitric oxide synthase gene polymorphism and maternal vascular adaptation to pregnancy

scientific article published on 01 December 2001

Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review

scientific article published on 3 October 2006

Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects

scientific article published on 8 March 2004

Endothelial nitric oxide synthase polymorphisms and hypertension

scientific article

Endothelial, sympathetic, and cardiac function in inherited (6R)-L-erythro-5,6,7,8-tetrahydro-L-biopterin deficiency

scientific article published on 11 October 2010

Erratum: Adiponectin and its association with bone mass accrual in childhood

scholarly article published in Journal of Bone and Mineral Research

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Estimation of bias in nongenetic observational studies using "mendelian triangulation"

scientific article published on 18 April 2006

Evaluating the causal relevance of diverse risk markers: horizontal systematic review

scientific article (publication date: 5 November 2009)

Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease

scientific article (publication date: June 2010)

Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial

scientific article published on 28 July 2011

Evaluation of Machine Learning Methods to Predict Coronary Artery Disease Using Metabolomic Data

scientific article

Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples

scientific article published on 20 March 2012

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D

scientific article (publication date: 2012)

Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies

scientific article published on 12 September 2011

Examining overweight and obesity as risk factors for common mental disorders using fat mass and obesity-associated (FTO) genotype-instrumented analysis: The Whitehall II Study, 1985-2004.

scientific article

Flipping the odds of drug development success through human genomics

Flow associated or flow mediated dilatation? More than just semantics ⬇️

scientific article published on July 1, 1997

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

scientific article published on 30 September 2011

Frequency of eNOS polymorphisms in the Colombian general population

scientific article

Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies

scientific article published on 2 December 2009

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip

scientific article published on 29 August 2013

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

scientific article

Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.

scientific article

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

scientific article

Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis

scientific article

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits

scientific article

Genetic drug target validation using Mendelian randomisation

scientific article published on 26 June 2020

Genetic evidence of assortative mating in humans

article

Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores

scientific article published on 23 November 2013

Genetic regulation of endothelial function

scientific article

Genetic risk factors and Mendelian randomization in cardiovascular disease

scientific article published on May 2015

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip

scientific article published on 28 April 2011

Genetic variants at chromosome 9p21 and risk of first versus subsequent coronary heart disease events: a systematic review and meta-analysis

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

scientific article published on 18 May 2011

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals

scientific article published on 29 July 2010

Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals

scientific article

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Genome-wide association study identifies five loci associated with lung function

scientific article

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

scientific article published on 13 October 2017

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

HAPRAP: a haplotype-based iterative method for statistical fine mapping using GWAS summary statistics

scientific article published on September 2016

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

scientific article published on 24 September 2014

Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

scientific article published on November 2010

Homocysteine and stroke: evidence on a causal link from mendelian randomisation

scientific article published in January 2005

How should we balance individual and population benefits of statins for preventing cardiovascular disease?

scientific article published on 26 January 2010

Human CRP Gene Polymorphism Influences CRP Levels

article

IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children

scientific article

IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.

scientific article published on 14 September 2011

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk

scientific article

Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene

scientific article

Identifying the genes for human hypertension.

scientific article

Impact of Selection Bias on Estimation of Subsequent Event Risk

scientific article published in October 2017

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Improving the odds of drug development success through human genomics: modelling study

scientific article published on 11 December 2019

Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability

scientific article

Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream

scientific article

Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress

scientific article published in October 2004

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies

scientific article published on 13 September 2012

Inhaled tiotropium bromide and risk of stroke

scientific article

Insight into the nature of the CRP-coronary event association using Mendelian randomization.

scientific article

Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk

scientific article

Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip

scientific article published on 8 November 2012

Interleukin-6 receptor pathways in abdominal aortic aneurysm

scientific article published on 30 October 2012

Invasive dental treatment and risk for vascular events: a self-controlled case series

scientific article

Investigating the genetic determinants of cardiovascular disease using candidate genes and meta-analysis of association studies

scientific article

Is a fatty liver (always or ever) bad for the heart?

scientific article published on 01 February 2018

Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease?

scientific article published on 05 July 2012

Is periodontal inflammation associated with raised blood pressure? Evidence from a National US survey

scientific article published in December 2010

Ischaemic stroke subtypes and their genetic basis: a comprehensive meta-analysis of small and large vessel stroke

scientific article published on 28 November 2008

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article

Levels of C-reactive protein in pregnant women who subsequently develop pre-eclampsia

scientific article published on 01 March 2002

Lifetime risk of developing coronary heart disease

scientific article published in March 1999

Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease riskThe opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of

scientific article published on 09 May 2006

Low eosinophil and low lymphocyte counts and the incidence of 12 cardiovascular diseases: a CALIBER cohort study

scientific article

Marginal role for 53 common genetic variants in cardiovascular disease prediction

scientific article published on 30 June 2016

Maternal endothelial function and serum concentrations of placental growth factor and soluble endoglin in women with abnormal placentation

scientific article published on 01 December 2008

Maternal serum concentration of soluble fms-like tyrosine kinase 1 and vascular endothelial growth factor in women with abnormal uterine artery Doppler and in those with fetal growth restriction

scientific article published on 27 April 2006

Mendelian Randomisation study of the influence of eGFR on coronary heart disease

scientific article published on 24 June 2016

Mendelian randomisation study for statin treatment – Authors' reply

scientific article published in The Lancet

Mendelian randomization of blood lipids for coronary heart disease

scientific article

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

scientific article published on 27 April 2011

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.

scientific article

Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance

scientific article published on 27 December 2019

Metabolic Profiling of Adiponectin Levels in Adults: Mendelian Randomization Analysis

scientific article published in December 2017

Metabolic profiles of socio-economic position: a multi-cohort analysis

scientific article published on 21 November 2020

Metabolic profiling of adiponectin levels in adults: Mendelian randomization analysis

scientific article published on 13 April 2017

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

scientific article published on March 2016

Mitochondrial oxidative stress, endothelial function and metabolic control in patients with type II diabetes and periodontitis: A randomised controlled clinical trial

scientific article published on 01 August 2018

Multilocus Bayesian meta-analysis of gene-disease associations

scientific article

Nature's randomised trials

scientific article published on 01 December 2005

Neutrophil Counts and Initial Presentation of 12 Cardiovascular Diseases: A CALIBER Cohort Study

scientific article published on March 2017

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Obesity causes cardiovascular diseases: adding to the weight of evidence

scientific article published on 01 January 2020

Optimisation of antihypertensive treatment by crossover rotation of four major classes

scientific article published on 01 June 1999

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis

scientific article published on 28 November 2017

Oral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis and cost-effectiveness analysis

scientific article published in March 2017

Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis

scientific article

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease

scientific article

PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease

scientific article published on 28 April 2017

PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry

scientific article

Periodontitis is associated with hypertension: a systematic review and meta-analysis

scientific article published on 24 September 2019

Pharmacogenetics: progress, pitfalls and clinical potential for coronary heart disease

scientific article published on 15 December 2005

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

scientific article published on 15 January 2016

Polymorphisms in endothelial nitric oxide synthase and atherogenesis: John French Lecture 2000.

scientific article

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

scientific article (publication date: 2013)

Positive association of tyrosine hydroxylase microsatellite marker to essential hypertension.

scientific article published on October 1998

Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions

scientific article published on 31 July 2008

Postinfectious myocarditis ⬇️

scientific article published on June 27, 1992

Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis

scientific article

Prevention of inflammation-induced endothelial dysfunction: a novel vasculo-protective action of aspirin

scientific article (publication date: 4 June 2002)

Primary prevention of cardiovascular disease: time to get more or less personal?

scientific article published in November 2009

Prognosis research strategy (PROGRESS) 4: stratified medicine research

scientific article (publication date: 5 February 2013)

Prognostic models for stable coronary artery disease based on electronic health record cohort of 102 023 patients.

scientific article published on 17 December 2013

Prospective study of placental angiogenic factors and maternal vascular function before and after preeclampsia and gestational hypertension

scientific article

Putting genomics into practice

scientific article published on 04 August 2011

Quantitative association between a newly identified molecular variant in the endothelin-2 gene and human essential hypertension.

scientific article published in September 1999

Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study

scientific article

Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans

scientific article published on 09 June 2016

Reply

Reply: limits of Mendelian randomization analyses in selection of secretory phospholipase A2-IIA as a valid therapeutic target for prevention of cardiovascular disease

scientific article published on 4 December 2013

Resistant Hypertension: Trials and Tribulations.

scientific article

Resolving inconsistency in the results of genetic association studies of cardiovascular disease

scientific article published on 01 September 2004

Risk of coronary heart disease and stroke in a large British cohort of patients with systemic lupus erythematosus

scientific article published on 18 May 2004

Screening for familial hypercholesterolaemia in childhood: Avon Longitudinal Study of Parents and Children (ALSPAC)

scientific article

Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis.

scientific article published in May 2017

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Selecting instruments for Mendelian randomization in the wake of genome-wide association studies

scientific article published on 24 June 2016

Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms

scientific article

Serum Conjugated Linoleic Acid and Risk of Incident Heart Failure in Older Men: The British Regional Heart Study

scientific article published on 6 January 2018

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

scientific article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Short-term vascular risk: time to take notice?

scientific article published on 4 May 2010

Sixty-five common genetic variants and prediction of type 2 diabetes

scientific article published on 4 December 2014

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

Systemic effects of periodontitis treatment in patients with type 2 diabetes: a 12 month, single-centre, investigator-masked, randomised trial

scientific article published on 24 October 2018

Tau gene and Parkinson's disease: a case-control study and meta-analysis

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The benefits of using genetic information to design prevention trials

scientific article published on 28 March 2013

The druggable genome and support for target identification and validation in drug development.

scientific article published in March 2017

The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome

scientific article published in May 2002

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults

scientific article

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

scientific article published on 14 March 2012

The role of infection in cardiovascular disease: more support but many questions remain

scientific article published on 30 April 2007

Threshold haemoglobin levels and the prognosis of stable coronary disease: two new cohorts and a systematic review and meta-analysis

scientific article (publication date: May 2011)

Time spent at blood pressure target and the risk of death and cardiovascular diseases ⬇️

scientific article published in PLoS ONE

Translating genomics into improved healthcare

scientific article

Translational phases of evidence in a prognostic biomarker: a systematic review and meta-analysis of natriuretic peptides and the prognosis of stable coronary disease

scientific article published on 03 March 2012

Treatment of periodontitis and endothelial function

scientific article published on 01 March 2007

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

scientific article

Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis

scientific article published on May 2009

UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER

scientific article published on 01 December 2019

Ultrasound-guided pigtail catheter drainage of malignant pericardial effusions

scientific article published on 01 January 1995

Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach.

scientific article published in December 2009

Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach

scientific article

Use of a strategy based on calculated risk scores in managing cardiovascular risk factors in a large British cohort of patients with systemic lupus erythematosus

scientific article published on 9 March 2009

Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays

scientific article

Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

scientific article published on 22 February 2013

Use of the self-controlled case series method in drug safety assessment

scientific article

Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study

scientific article

Utility of genetic determinants of lipids and cardiovascular events in assessing risk

scientific article published on 15 February 2011

Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies

scientific article

Variation in Interleukin 6 Receptor Gene Associates With Risk of Crohn's Disease and Ulcerative Colitis

article

Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people

scientific article

Ximelagatran or warfarin in atrial fibrillation?

scientific article (publication date: 28 February 2004)

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