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List of works by Alexander Thielen

A Follow-Up of the Multicenter Collaborative Study on HIV-1 Drug Resistance and Tropism Testing Using 454 Ultra Deep Pyrosequencing

scientific article

APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1.

scientific article published on 15 May 2011

Added Value of Deep Sequencing Relative to Population Sequencing in Heavily Pre-Treated HIV-1-Infected Subjects ⬇️

scientific article published on May 13, 2011

Correlation between genotypic (V3 population sequencing) and phenotypic (Trofile ES) methods of characterizing co-receptor usage of HIV-1 from 200 treatment-naïve HIV patients screened for Study A4001078.

scientific article

Decreased HIV diversity after allogeneic stem cell transplantation of an HIV-1 infected patient: a case report

scientific article published on 8 March 2010

Deep sequencing to infer HIV-1 co-receptor usage: application to three clinical trials of maraviroc in treatment-experienced patients

scientific article published on January 2011

Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure

scientific article published on 29 September 2010

Emergent HIV-1 Drug Resistance Mutations Were Not Present at Low-Frequency at Baseline in Non-Nucleoside Reverse Transcriptase Inhibitor-Treated Subjects in the STaR Study

scientific article

Geno2pheno[454]: a Web server for the prediction of HIV-1 coreceptor usage from next-generation sequencing data

scientific article

Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis ⬇️

scientific article

HIV-1 mutational pathways under multidrug therapy

scientific article published on 27 July 2011

HIV-1 tropism testing in subjects achieving undetectable HIV-1 RNA: diagnostic accuracy, viral evolution and compartmentalization

scientific article

High concordance between the position-specific scoring matrix and geno2pheno algorithms for genotypic interpretation of HIV-1 tropism: V3 length as the major cause of disagreement

scientific article published on 06 July 2011

Improved detection of CXCR4-using HIV by V3 genotyping: application of population-based and "deep" sequencing to plasma RNA and proviral DNA.

scientific article published in August 2010

In-depth analysis of G-to-A hypermutation rate in HIV-1 env DNA induced by endogenous APOBEC3 proteins using massively parallel sequencing

scientific article published on 24 November 2010

Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies ⬇️

scientific article published on October 23, 2010

Population-based sequencing of the V3-loop can predict the virological response to maraviroc in treatment-naive patients of the MERIT trial

scientific article published in November 2012

Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach

scientific article published on December 2011

Therapeutic Immune Recovery and Reduction of CXCR4-Tropic HIV-1.

scientific article

V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.

scientific article

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