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List of works by José A Sánchez-Alcázar

Activation of the Mitochondrial Unfolded Protein Response: A New Therapeutic Target?

scientific article published in 2022

Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs ⬇️

scientific article published on November 1, 2010

Aging-related changes in inflammatory and LKB1/AMPK gene expression in fibromyalgia patients.

scientific article published on 19 March 2014

Amitriptyline induces coenzyme Q deficiency and oxidative damage in mouse lung and liver

scientific article published on 09 April 2011

Apoptotic cells subjected to cold/warming exposure disorganize apoptotic microtubule network and undergo secondary necrosis

scientific article

Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria ⬇️

scientific article published on April 1, 2011

Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis.

scientific article published on 7 March 2013

Atherosclerosis and Coenzyme Q10

scientific article published on 20 October 2019

Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis.

scientific article

Cerebellar ataxia with coenzyme Q10 deficiency: Diagnosis and follow-up after coenzyme Q10 supplementation

Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines.

scientific article published on 13 December 2005

Clinical applications of coenzyme Q10.

scientific article published on January 2014

Clinical, biochemical and molecular aspects of cerebellar ataxia and Coenzyme Q10 deficiency.

scientific article published on January 2007

Coenzyme Q(10): a novel therapeutic approach for Fibromyalgia? case series with 5 patients

scientific article published on 07 April 2011

Coenzyme Q10 deficiency associated with a mitochondrial DNA depletion syndrome: a case report

scientific article published on 03 December 2008

Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia.

scientific article published on 25 December 2008

Coenzyme Q10: Novel Formulations and Medical Trends

scientific article published on 10 November 2020

Coenzyme q10 regulates serotonin levels and depressive symptoms in fibromyalgia patients: results of a small clinical trial.

scientific article published in April 2014

Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.

scientific article published in April 2003

Cytotoxic effects of amitriptyline in human fibroblasts.

scientific article published on 26 September 2007

Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives

scientific article published on 05 May 2021

Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis

scientific article published on 11 November 2017

Effects of Ethanol and Dexamethasone on Epidermis Examined by in Vitro 31P Magnetic Resonance Spectroscopy

scientific article published on 01 February 1998

Emerging roles of apoptotic microtubules during the execution phase of apoptosis.

scientific article published on 18 September 2015

G Proteins Are Involved in the Suppression of Collagen α1(I) Gene Expression in Cultured Rat Hepatic Stellate Cells ⬇️

scientific article published on March 1, 1998

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Increased mitochondrial cytochrome c levels and mitochondrial hyperpolarization precede camptothecin-induced apoptosis in Jurkat cells

scientific article published in November 2000

Is inflammation a mitochondrial dysfunction-dependent event in fibromyalgia?

scientific article published on 16 November 2012

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

scientific article published on 4 September 2012

Metformin and caloric restriction induce an AMPK-dependent restoration of mitochondrial dysfunction in fibroblasts from Fibromyalgia patients.

scientific article published on 14 March 2015

Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis

scientific journal article

Mitochondrial dysfunction in skin biopsies and blood mononuclear cells from two cases of fibromyalgia patients.

scientific article published in July 2010

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

scientific article published in February 2014

Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient

scientific article published on 14 August 2012

Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients.

scientific article published on 26 November 2011

Oxidative stress correlates with headache symptoms in fibromyalgia: coenzyme Q₁₀ effect on clinical improvement

scientific article

Oxidative stress, mitochondrial dysfunction and, inflammation common events in skin of patients with Fibromyalgia

scientific article published on 7 February 2015

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system.

scientific article published on 19 August 2014

Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation

scientific article published on 01 September 2018

Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease

scientific article published on 5 June 2015

Precision Medicine in Rare Diseases

scientific article published on 13 November 2020

Reactive oxygen species mediate the down-regulation of mitochondrial transcripts and proteins by tumour necrosis factor-alpha in L929 cells.

scientific article published in March 2003

Recovery of MERRF fibroblasts and cybrids pathophysiology by coenzyme Q10.

scientific article

Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease

scientific article

Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts

scientific article published on 06 May 2011

Stabilization of apoptotic cells: generation of zombie cells.

scientific article published on 14 August 2014

Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier.

scientific article published in April 2014

The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye.

scientific article

The hypoxic preconditioning agent deferoxamine induces poly(ADP-ribose) polymerase-1-dependent inhibition of the mitochondrial respiratory chain.

scientific article

Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochromebof the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells

scientific article published in Journal of Biological Chemistry

Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein ⬇️

scientific article published on August 1, 1997

Tumor necrosis factor-alpha increases ATP content in metabolically inhibited L929 cells preceding cell death.

scientific article

UPRmt activation improves pathological alterations in cellular models of mitochondrial diseases

scientific article published in 2022

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