List of works - François R Jornayvaz

A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain

scientific article

A rare cause of hypertestosteronemia in a 68-year-old patient: a Leydig cell tumor due to a somatic GNAS (guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1)-activating mutation

scientific article published on 20 October 2011

AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.

scientific article published on 20 October 2017

ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content.

scientific article

Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance

scientific article

Artificial sweeteners and diabetes: friends or foes?

scientific article published on June 2015

CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance

scientific article published on 9 January 2013

Capsule commentary on Patrick et al., trends in insulin initiation and treatment intensification among patients with type 2 diabetes.

scientific article published on February 2014

Cardiovascular safety of antidiabetics

scientific article published on June 2016

Cellular mechanism by which estradiol protects female ovariectomized mice from high-fat diet-induced hepatic and muscle insulin resistance

scientific article published on 30 January 2013

Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice

scientific article

Classification of diabetes: an increasing heterogeneity

scientific article

Consequences of the Adoption of the IADPSG versus Carpenter and Coustan Criteria to Diagnose Gestational Diabetes: A Before-After Comparison

scientific article published on 26 September 2018

Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice

scholarly article by Andreas L. Birkenfeld et al published October 2011 in Cell Metabolism

Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice

scientific article

Development of insulin resistance in mice lacking PGC-1α in adipose tissues.

scientific article

Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection.

scientific article published on 10 March 2016

Diet, Lifestyle, and Long-Term Weight Gain ⬇️

scientific article published on September 15, 2011

Diets and nonalcoholic fatty liver disease: the good and the bad.

scientific article

Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice

scientific article published on 28 November 2011

Effectiveness and safety of insulin glargine 300 U/mL in insulin-naïve patients with type 2 diabetes after failure of oral therapy in a real-world setting

scientific article published on 24 January 2020

Effects of Antidiabetic Drugs on Gut Microbiota Composition

scientific article

Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies.

scientific article

Endocrine causes of nonalcoholic fatty liver disease

scientific article

Enhanced fasting glucose turnover in mice with disrupted action of TUG protein in skeletal muscle

scientific article published on 06 June 2013

Fasting glycaemia to simplify screening for gestational diabetes

scientific article

Faut-il prescrire plus d’inhibiteurs SGLT-2 ?

scientific article published on 01 May 2019

Fibroblast Growth Factor 15/19 - From Basic Functions to Therapeutic Perspectives

scientific article published on 01 December 2018

Fibroblast growth factor 21, ketogenic diets, and insulin resistance

scientific article published on 01 September 2011

Free Fatty Acids Impair FGF21 Action in HepG2 Cells.

scientific article

GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone.

scientific article published on 9 September 2016

Grip strength is not associated with incident type 2 diabetes mellitus in healthy adults: The CoLaus study.

scientific article published on 18 August 2017

Hepatic insulin resistance and increased hepatic glucose production in mice lacking Fgf21.

scientific article

Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

scientific article

Increased FGF21 plasma levels in humans with sepsis and SIRS.

scientific article published on 17 September 2013

Inflammation as a potential link between nonalcoholic fatty liver disease and insulin resistance.

scientific article published on 28 August 2013

Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism

scientific article

Ketogenic Diet Impairs FGF21 Signaling and Promotes Differential Inflammatory Responses in the Liver and White Adipose Tissue

scientific article published on 14 May 2015

Ketogenic diets : the miraculous solution ?

scientific article published in May 2017

Leptin as a Potential Regulator of FGF21.

scientific article published on 17 March 2016

Metabolic syndrome and nonalcoholic fatty liver disease: Is insulin resistance the link?

scientific article published on 24 February 2015

Metformin: new data for an old molecule

scientific article

Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism

scientific article published on 14 November 2019

Muscle-specific activation of Ca(2+)/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice.

scientific article published on 11 April 2014

News in diabetology 2017

scientific article published in January 2018

Nonalcoholic fatty liver disease burden - Switzerland 2018-2030

scientific article published on 17 December 2019

Observance thérapeutique et empilage médicamenteux

scientific article published in May 2018

Ostα-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity.

scientific article published on 31 December 2013

Preserving of Postnatal Leptin Signaling in Obesity-Resistant Lou/C Rats following a Perinatal High-Fat Diet.

scientific article

Real-World Effectiveness of Insulin Glargine 300 Initiation in Switzerland

scientific article published on 03 July 2020

Regulation of mitochondrial biogenesis

scientific article

Reply to Monetti et al.: Hepatic steatosis and diacylglycerol-mediated hepatic insulin resistance in acyl-CoA:diacylglycerol acyltransferase 2 (DGAT2) transgenic mice.

scientific article

SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function ⬇️

scientific article

Salivary cortisol is not associated with incident insulin resistance or type 2 diabetes mellitus

scientific article published on 01 July 2019

Second-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance

scientific article published on 7 December 2015

Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.

scientific article

The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome.

scientific article published on August 2010

Thirteen-year trends in the prevalence of diabetes in an urban region of Switzerland: a population-based study

scientific article published on 08 December 2019

Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance

scientific article

Traitement du diabète : quand faire appel au diabétologue ?

Translational Aspects of Diet and Non-Alcoholic Fatty Liver Disease

scientific article published on 28 September 2017

Treatment challenges in type 1 diabetes after roux-en-Y gastric bypass.

scientific article

Use of Dipeptidyl-Peptidase IV Inhibitors and Bullous Pemphigoid.

scientific article published on 18 October 2017

Value of continuous glucose monitoring in type 2 diabetic patients

scientific article published in May 2017

Weight and mortality in adults with diabetes.

scientific article

[Chronic diarrhea in adults: diagnostic strategies]

scientific article published on 01 December 2004

[Chronic kidney disease and new antidiabetic drugs : an overview in 2019]

scientific article published on 01 May 2019

[Chronic liver diseases and diabetes]

[Combined treatment of insulin and GLP-1 analogs: what do we expect?]

[Diabetes and non-alcoholic fatty liver disease]

scientific article published on 01 June 2012

[Diabetes in 2015: constantly increasing, but with enlarged therapeutics options]

scientific article published on 01 June 2015

[Diabetes mellitus secondary to an endocrine pathology : when to think about it ?]

scientific article

[Dyslipidemia management in patients with type 1 diabetes]

scientific article published in May 2018

[Gestational diabetes--what are the non-medical approaches?]

[Management of cardiovascular diseases in adults from 1999 to 2014: what has really changed?].

scientific article published in November 2015

[News in Diabetology 2019]

scientific article published on 01 January 2020

[News in diabetology 2015]

scientific article published in January 2016

[News in diabetology 2016].

scientific article

[News in diabetology 2018]

scientific article published on 01 January 2019

[Optimal hospital-home transition for a type 2 diabetic patient : some tools]

scientific article published in May 2018

[Pre-gestational diabetes : an increasingly common entity]

scientific article published in May 2018

[Sleep and diabetes]

scientific article published on 01 June 2012

[Transition in diabetology]

[Type 1 diabetes, physical activity and novel technology]

scientific article published in May 2018

[Use of new antidiabetics in the elderly population].

scientific article published in June 2016

β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.

scientific article

List of works by François R Jornayvaz

A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain

A rare cause of hypertestosteronemia in a 68-year-old patient: a Leydig cell tumor due to a somatic GNAS (guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1)-activating mutation

AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.

ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content.

Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance

Artificial sweeteners and diabetes: friends or foes?

CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance

Capsule commentary on Patrick et al., trends in insulin initiation and treatment intensification among patients with type 2 diabetes.

Cardiovascular safety of antidiabetics

Cellular mechanism by which estradiol protects female ovariectomized mice from high-fat diet-induced hepatic and muscle insulin resistance

Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice

Classification of diabetes: an increasing heterogeneity

Consequences of the Adoption of the IADPSG versus Carpenter and Coustan Criteria to Diagnose Gestational Diabetes: A Before-After Comparison

Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice

Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice

Development of insulin resistance in mice lacking PGC-1α in adipose tissues.

Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection.

Diet, Lifestyle, and Long-Term Weight Gain ⬇️

Diets and nonalcoholic fatty liver disease: the good and the bad.

Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice

Effectiveness and safety of insulin glargine 300 U/mL in insulin-naïve patients with type 2 diabetes after failure of oral therapy in a real-world setting

Effects of Antidiabetic Drugs on Gut Microbiota Composition

Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies.

Endocrine causes of nonalcoholic fatty liver disease

Enhanced fasting glucose turnover in mice with disrupted action of TUG protein in skeletal muscle

Fasting glycaemia to simplify screening for gestational diabetes

Faut-il prescrire plus d’inhibiteurs SGLT-2 ?

Fibroblast Growth Factor 15/19 - From Basic Functions to Therapeutic Perspectives

Fibroblast growth factor 21, ketogenic diets, and insulin resistance

Free Fatty Acids Impair FGF21 Action in HepG2 Cells.

GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone.

Grip strength is not associated with incident type 2 diabetes mellitus in healthy adults: The CoLaus study.

Hepatic insulin resistance and increased hepatic glucose production in mice lacking Fgf21.

Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

Increased FGF21 plasma levels in humans with sepsis and SIRS.

Inflammation as a potential link between nonalcoholic fatty liver disease and insulin resistance.

Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism

Ketogenic Diet Impairs FGF21 Signaling and Promotes Differential Inflammatory Responses in the Liver and White Adipose Tissue

Ketogenic diets : the miraculous solution ?

Leptin as a Potential Regulator of FGF21.

Metabolic syndrome and nonalcoholic fatty liver disease: Is insulin resistance the link?

Metformin: new data for an old molecule

Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism

Muscle-specific activation of Ca(2+)/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice.

News in diabetology 2017

Nonalcoholic fatty liver disease burden - Switzerland 2018-2030

Observance thérapeutique et empilage médicamenteux

Ostα-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity.

Preserving of Postnatal Leptin Signaling in Obesity-Resistant Lou/C Rats following a Perinatal High-Fat Diet.

Real-World Effectiveness of Insulin Glargine 300 Initiation in Switzerland

Regulation of mitochondrial biogenesis

Reply to Monetti et al.: Hepatic steatosis and diacylglycerol-mediated hepatic insulin resistance in acyl-CoA:diacylglycerol acyltransferase 2 (DGAT2) transgenic mice.

SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function ⬇️

Salivary cortisol is not associated with incident insulin resistance or type 2 diabetes mellitus

Second-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance

Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.

The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome.

Thirteen-year trends in the prevalence of diabetes in an urban region of Switzerland: a population-based study

Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance

Traitement du diabète : quand faire appel au diabétologue ?

Translational Aspects of Diet and Non-Alcoholic Fatty Liver Disease

Treatment challenges in type 1 diabetes after roux-en-Y gastric bypass.

Use of Dipeptidyl-Peptidase IV Inhibitors and Bullous Pemphigoid.

Value of continuous glucose monitoring in type 2 diabetic patients

Weight and mortality in adults with diabetes.

[Chronic diarrhea in adults: diagnostic strategies]

[Chronic kidney disease and new antidiabetic drugs : an overview in 2019]

[Chronic liver diseases and diabetes]

[Combined treatment of insulin and GLP-1 analogs: what do we expect?]

[Diabetes and non-alcoholic fatty liver disease]

[Diabetes in 2015: constantly increasing, but with enlarged therapeutics options]

[Diabetes mellitus secondary to an endocrine pathology : when to think about it ?]

[Dyslipidemia management in patients with type 1 diabetes]

[Gestational diabetes--what are the non-medical approaches?]

[Management of cardiovascular diseases in adults from 1999 to 2014: what has really changed?].

[News in Diabetology 2019]

[News in diabetology 2015]

[News in diabetology 2016].

[News in diabetology 2018]