List of works - April L Risinger

Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines

scientific article published on 04 March 2019

CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells

scientific article published on 06 October 2020

Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands ⬇️

scientific article published on 20 March 2019

Elucidating target specificity of the taccalonolide covalent microtubule stabilizers employing a combinatorial chemical approach

scientific article published on 31 January 2020

Fluorescence spectral shape analysis for nucleotide identification

scientific article published on 15 July 2019

Identification of C-6 as a New Site for Linker Conjugation to the Taccalonolide Microtubule Stabilizers

scientific article published on 25 February 2019

In Situ Ring Contraction and Transformation of the Rhizoxin Macrocycle through an Abiotic Pathway

scientific article published on 13 March 2019

Janus Compounds, 5-Chloro-N⁴-methyl-N⁴-aryl-9H-pyrimido[4,5-b]indole-2,4-diamines, Cause Both Microtubule Depolymerizing and Stabilizing Effects.

scientific article

Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Triple Negative Breast Cancer

scientific article published on 08 June 2020

Microtubule-Targeting Drugs: More than Antimitotics

scientific article published on 05 March 2019

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

scientific article published on 23 January 2017

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy.

scientific article published on 10 November 2017

Taccalonolide Microtubule Stabilizers Generated Using Semisynthesis Define the Effects of Mono Acyloxy Moieties at C-7 or C-15 and Disubstitutions at C-7 and C-25.

scientific article published on 23 January 2018

Targeting and extending the eukaryotic druggable genome with natural products: cytoskeletal targets of natural products

scientific article published on 25 November 2019

Triple-Negative Breast Cancer Cells Exhibit Differential Sensitivity to Cardenolides from Calotropis gigantea

scientific article published on 10 July 2020

Triple-negative breast cancer cell line sensitivity to englerin A identifies a new, targetable subtype

scientific article published on 22 June 2019

Using the Cancer Dependency Map to Identify the Mechanism of Action of a Cytotoxic Alkenyl Derivative from the Fruit of Choerospondias axillaris

scientific article published on 27 February 2020

List of works by April L Risinger