Search filters

List of works by Mark L Chiu

1H NMR investigation of distal mutant deoxy myoglobins. Interpretation of proximal His contact shifts in terms of a localized distal water molecule.

scientific article published on November 1994

1H NMR study of the solution molecular and electronic structure of Escherichia coli ferricytochrome b562: evidence for S = 1/2 in equilibrium S = 5/2 spin equilibrium for intact His/Met ligation.

scientific article

1H and 15N resonance assignments and secondary structure of the carbon monoxide complex of sperm whale myoglobin

scientific article published on 01 July 1994

A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors.

scientific article

An efficient process of generating bispecific antibodies via controlled Fab-arm exchange using culture supernatants

scientific article published on 27 January 2016

Antibody Structure and Function: The Basis for Engineering Therapeutics

scientific article published on 03 December 2019

Broad spectrum thiopeptide recognition specificity of the Streptomyces lividans TipAL protein and its role in regulating gene expression

scientific article published in July 1999

Characterization of the covalent binding of thiostrepton to a thiostrepton-induced protein from Streptomyces lividans

scientific article published on 01 February 1996

Correlation between the steric bulk of the distal E7 and E11 residues and the tilt of the FeCN unit in cyanometmyoglobin as determined by NMR from the orientation of the magnetic axes in single and double point mutants.

scientific article published in May 1994

Cross-arm binding efficiency of an EGFR x c-Met bispecific antibody.

scientific article published on 13 January 2016

Crystallization in cubo: general applicability to membrane proteins

scientific article published on 01 June 2000

Crystallization of bacteriorhodopsin solubilized by a tripod amphiphile.

scientific article

Development of ELISA to measure TRPV1 protein in rat tissues.

scientific article published on 6 July 2011

Diffusion of Soluble Aggregates of THIOMABs and Bispecific Antibodies in Serum

scientific article published on 10 April 2017

Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models

scientific article

Engineering antibody therapeutics

scientific article

Expression and purification of human TRPV1 in baculovirus-infected insect cells for structural studies.

scientific article

Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody.

scientific article published on 17 November 2016

Fc-mediated activity of EGFR x c-Met bispecific antibody JNJ-61186372 enhanced killing of lung cancer cells

scientific article published on 27 October 2016

FcγRII-binding Centyrins mediate agonism and antibody-dependent cellular phagocytosis when fused to an anti-OX40 antibody.

scientific article published on 23 January 2018

Functional optimization of agonistic antibodies to OX40 receptor with novel Fc mutations to promote antibody multimerization

scientific article published on 31 July 2017

High-throughput assay for measuring monoclonal antibody self-association and aggregation in serum

scientific article published on 6 March 2015

Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody

scientific article published on 10 August 2015

Introduction to membrane proteins.

scientific article published on February 2012

Ligand-induced changes in the Streptomyces lividans TipAL protein imply an alternative mechanism of transcriptional activation for MerR-like proteins.

scientific article published in October 2001

Lipidic Cubic Phases: New Matrices for the Three-Dimensional Crystallization of Membrane Proteins

scientific article published in January 1998

Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance.

scientific article published on 26 October 2016

Quantification of TRPV1 protein levels in rat tissues to understand its physiological roles

scientific article published on 14 July 2012

Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity.

scientific article published in May 2004

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.

scientific article published on March 2011

The heme iron coordination complex in His64(E7)Tyr recombinant sperm whale myoglobin

scientific article published in September 1994

Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody.

scientific article published on 3 February 2018

Paulina is supported by:

About Paulina

Help