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List of works by Lei S Qi

A CRISPR-dCas Toolbox for Genetic Engineering and Synthetic Biology

scientific article published on 26 June 2018

A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription.

scientific article published on 22 September 2017

A protein-tagging system for signal amplification in gene expression and fluorescence imaging

scientific article

A versatile framework for microbial engineering using synthetic non-coding RNAs

scientific article published on May 2014

An Introduction to CRISPR Technology for Genome Activation and Repression in Mammalian Cells

scientific article published on 4 January 2016

An adaptor from translational to transcriptional control enables predictable assembly of complex regulation

scientific article published on 30 September 2012

Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells

scientific article published in Nature Communications

CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming

scientific article published on 11 October 2018

CRISPR Technology for Genome Activation and Repression in Mammalian Cells

scientific article published on 4 January 2016

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

scientific article

CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency

scientific article published on 9 January 2018

CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization

scientific article published on 11 October 2018

CRISPR-mediated live imaging of genome editing and transcription

scientific article published on 05 September 2019

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

scientific article

CRISPR/Cas9 for Human Genome Engineering and Disease Research.

scientific article published on 23 May 2016

CRISPhieRmix: a hierarchical mixture model for CRISPR pooled screens

scientific article

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

scientific article

Complex transcriptional modulation with orthogonal and inducible dCas9 regulators.

scientific article

DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells.

scientific article published on 12 July 2018

Development of CRISPR as a prophylactic strategy to combat novel coronavirus and influenza

scientific article (preprint)

Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system

scientific article published on 20 December 2017

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds

scientific article

Engineering naturally occurring trans-acting non-coding RNAs to sense molecular signals

scientific article

Evolution at the Cutting Edge: CRISPR-Mediated Directed Evolution

scientific article published on 01 November 2018

Genetic and epigenetic control of gene expression by CRISPR-Cas systems

scientific article

Genetic interaction mapping in mammalian cells using CRISPR interference

scientific article published on 8 May 2017

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

scientific article

Identification of Novel Regulatory Genes in APAP Induced Hepatocyte Toxicity by a Genome-Wide CRISPR-Cas9 Screen

scientific article published in Scientific Reports

Identification of cell context-dependent YAP-associated proteins reveals β1 and β4 integrin mediate YAP translocation independently of cell spreading

scientific article published on 20 November 2019

Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites

scientific article published on 19 May 2020

Multiplexed Dynamic Imaging of Genomic Loci by Combined CRISPR Imaging and DNA Sequential FISH.

scientific article

RNA processing enables predictable programming of gene expression

scientific article published on 16 September 2012

Rationally designed families of orthogonal RNA regulators of translation

scientific article published on 25 March 2012

Regulation of transcription by unnatural amino acids

scientific article published on 16 January 2011

Repurposing CRISPR System for Transcriptional Activation

scientific article

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

scientific article (publication date: 28 February 2013)

Reversible Disruption of Specific Transcription Factor-DNA Interactions Using CRISPR/Cas9

scientific article published on 01 May 2019

Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems

scientific article published on 01 July 2019

Small molecules enhance CRISPR genome editing in pluripotent stem cells.

scientific article

Specific gene repression by CRISPRi system transferred through bacterial conjugation

scientific article

Toward scalable parts families for predictable design of biological circuits

scientific article

Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

scientific article published in 2020

Using CRISPR-ERA Webserver for sgRNA Design

publication published on 05 September 2017

Versatile RNA-sensing transcriptional regulators for engineering genetic networks

scientific article

When genome editing goes off-target

scientific article

YAP-independent mechanotransduction drives breast cancer progression

scientific article published on 23 April 2019

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