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List of works by Murat Saparbaev

3, N 4 -ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase ⬇️

scientific article published on July 21, 1998

A molecular beacon assay for measuring base excision repair activities.

scientific article published on June 2004

Aberrant base excision repair pathway of oxidatively damaged DNA: Implications for degenerative diseases.

scientific article published on 24 November 2016

Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands.

scientific article

Aberrant repair initiated by the adenine-DNA glycosylase does not play a role in UV-induced mutagenesis in

scientific article published on 05 December 2018

African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA.

scientific article

Antimutagenic role of base-excision repair enzymes upon free radical-induced DNA damage ⬇️

scientific article published on June 18, 1998

Apoptotic topoisomerase I-DNA complexes induced by staurosporine-mediated oxygen radicals.

scientific article published on 22 September 2004

Characterization of Aspergillus niger endo-1,4-β-glucanase ENG1 secreted from Saccharomyces cerevisiae using different expression vectors.

scientific article published on 11 June 2015

Characterization of DNA substrate specificities of apurinic/apyrimidinic endonucleases from Mycobacterium tuberculosis

scientific article published on 22 May 2015

Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori

scientific article published in PLoS ONE

Conformational Dynamics of DNA Repair by Escherichia coli Endonuclease III

scientific article published on 13 April 2015

Coupling of the nucleotide incision and 3'-->5' exonuclease activities in Escherichia coli endonuclease IV: Structural and genetic evidences.

scientific article published on 12 September 2009

DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides.

scientific article published on 3 June 2010

Direct DNA Lesion Reversal and Excision Repair in Escherichia coli.

scientific article published on February 2013

Enzymology of repair of etheno-adducts.

scientific article published on October 2003

Excision of 8-oxoguanine from methylated CpG dinucleotides by human 8-oxoguanine DNA glycosylase.

scientific article published on 13 August 2013

Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3'-diesterase-deficient strain

scientific article published on 09 August 2014

Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity

scientific article

High resolution characterization of formamidopyrimidine-DNA glycosylase interaction with its substrate by chemical cross-linking and mass spectrometry using substrate analogs.

scientific article published on 22 August 2006

Impact of pyrophosphate and O-ethyl-substituted pyrophosphate groups on DNA structure

scientific article published on 01 January 2007

Initiation of 8-oxoguanine base excision repair within trinucleotide tandem repeats.

scientific article

Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases

scientific article

Kinetic mechanism of human apurinic/apyrimidinic endonuclease action in nucleotide incision repair

scientific article published on 01 February 2011

Lipid peroxidation product 4-hydroxy-2-nonenal modulates base excision repair in human cells.

scientific article

Lys98 Substitution in Human AP Endonuclease 1 Affects the Kinetic Mechanism of Enzyme Action in Base Excision and Nucleotide Incision Repair Pathways ⬇️

scientific article published on January 1, 2011

Mechanism of stimulation of DNA binding of the transcription factors by human apurinic/apyrimidinic endonuclease 1, APE1

scientific article published on 31 August 2019

Mechanistic insight into the role of Poly(ADP-ribosyl)ation in DNA topology modulation and response to DNA damage

scientific article published on 01 February 2020

New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways.

scientific article

Oxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways

scientific article published on 22 April 2015

Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro.

scientific article published on 28 July 2016

Pre-steady-state fluorescence analysis of damaged DNA transfer from human DNA glycosylases to AP endonuclease APE1.

scientific article published on 31 July 2014

Pre-steady-state kinetic analysis of damage recognition by human single-strand selective monofunctional uracil-DNA glycosylase SMUG1.

scientific article

Predictive biomarkers for cancer therapy with PARP inhibitors.

scientific article published on 16 September 2013

Role of mismatch-specific uracil-DNA glycosylase in repair of 3,N4-ethenocytosine in vivo.

scientific article published in December 2004

Step-by-step mechanism of DNA damage recognition by human 8-oxoguanine DNA glycosylase.

scientific article

Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA

scientific article

Substrate specificity of homogeneous monkeypox virus uracil-DNA glycosylase.

scientific article published on 2 October 2007

TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.

scientific article published on 24 May 2016

The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae.

scientific article

The Human DNA glycosylases NEIL1 and NEIL3 Excise Psoralen-Induced DNA-DNA Cross-Links in a Four-Stranded DNA Structure.

scientific article published on 12 December 2017

The Ring Fragmentation Product of Thymidine C5-Hydrate When Present in DNA Is Repaired by the Escherichia coli Fpg and Nth Proteins ⬇️

scientific article published on May 26, 1998

The major Arabidopsis thaliana apurinic/apyrimidinic endonuclease, ARP is involved in the plant nucleotide incision repair pathway

scientific article published on 29 October 2016

The mechanism of human tyrosyl-DNA phosphodiesterase 1 in the cleavage of AP site and its synthetic analogs.

scientific article published on 31 October 2013

The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation

scientific article published on 11 February 2018

Two sequential phosphates 3' adjacent to the 8-oxoguanosine are crucial for lesion excision by E. coli Fpg protein and human 8-oxoguanine-DNA glycosylase.

scientific article published on 13 June 2005

Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells

scientific article

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