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List of works by Matthew R. Hepworth

A helminth immunomodulator exploits host signaling events to regulate cytokine production in macrophages

scientific article

A matter of timing: Early, not chronic phase intestinal nematode infection restrains control of a concurrent enteric protozoan infection ⬇️

scientific article published on October 1, 2010

A novel regulatory macrophage induced by a helminth molecule instructs IL-10 in CD4+ T cells and protects against mucosal inflammation.

scientific article published on 14 January 2015

Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria

article

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation

scientific article published on 04 April 2016

CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.

scientific article

Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

scientific article

Corrigendum: CCR7-dependent trafficking of RORγ(+) ILCs creates a unique microenvironment within mucosal draining lymph nodes

scientific article published on 29 March 2016

Disruption of Th2 immunity results in a gender-specific expansion of IL-13 producing accessory NK cells during helminth infection.

scientific article published on 19 August 2009

Effect of glycosylphosphatidylinositol (GPI)-phospholipase D overexpression on GPI metabolism.

scientific article published on March 2004

Establishment of nematode infection despite increased Th2 responses and immunopathology after selective depletion of Foxp3+ cells

scientific article published in November 2009

Frequencies of regulatory T cells in the peripheral blood of dogs with primary immune-mediated thrombocytopenia and chronic enteropathy: a pilot study

scientific article

Functional and phenotypic heterogeneity of group 3 innate lymphoid cells

scientific article published on 9 December 2016

Functional interactions between innate lymphoid cells and adaptive immunity

scientific article published on 26 July 2019

Group 3 Innate Lymphoid Cells: Communications Hubs of the Intestinal Immune System

scientific article published on 16 October 2017

Group 3 innate lymphoid cells: regulating host-commensal bacteria interactions in inflammation and cancer

scientific article published on 07 October 2015

IL-22 mediates host defense against an intestinal intracellular parasite in the absence of IFN-γ at the cost of Th17-driven immunopathology

scientific article published on 20 January 2012

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites

scientific article published on 03 October 2019

Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells

scientific article published on 23 April 2015

Immunoregulatory Sensory Circuits in Group 3 Innate Lymphoid Cell (ILC3) Function and Tissue Homeostasis

scientific article published on 06 February 2020

Innate Lymphoid Cell Regulation: Meeting the Long-Lost Cousin

scientific article

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

scientific article published on 22 May 2013

Looking into the future of Trichuris suis therapy.

scientific article

Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism

scientific article

Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines

scientific article published on 9 April 2012

Orchestration of intestinal homeostasis and tolerance by group 3 innate lymphoid cells.

scientific article

Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation

scientific article published in January 2018

Reciprocal transcription factor networks govern tissue-resident ILC3 subset function and identity

scientific article published on 23 September 2021

Regulation of the adaptive immune system by innate lymphoid cells

scientific article

Regulation of type 2 immunity to helminths by mast cells

scientific article

Regulatory T cells confer a circadian signature on inflammatory arthritis

scientific article published on 03 April 2020

TSLP Elicits IL-33–Independent Innate Lymphoid Cell Responses to Promote Skin Inflammation ⬇️

scientific article published on January 30, 2013

The role of sex hormones in the development of Th2 immunity in a gender-biased model of Trichuris muris infection

scientific article published on February 2010

Therapeutic potential of larval excretory/secretory proteins of the pig whipworm Trichuris suis in allergic disease

scientific article published on 6 September 2014

Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells

scientific article

Worming our way closer to the clinic.

scientific article published on 15 July 2012

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