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List of works by James A. Fraser

A quantitative analysis of cell volume and resting potential determination and regulation in excitable cells

scientific article published on 8 July 2004

A quantitative analysis of the effect of cycle length on arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts.

scientific article published on 17 April 2007

Acute atrial arrhythmogenesis in murine hearts following enhanced extracellular Ca(2+) entry depends on intracellular Ca(2+) stores.

scientific article

Alterations in calcium homeostasis reduce membrane excitability in amphibian skeletal muscle

scientific article published on 6 September 2006

Alterations in triad ultrastructure following repetitive stimulation and intracellular changes associated with exercise in amphibian skeletal muscle.

scientific article published on 2 March 2007

Altered sinoatrial node function and intra-atrial conduction in murine gain-of-function Scn5a+/ΔKPQ hearts suggest an overlap syndrome.

scientific article published on 27 January 2012

An analysis of the relationships between subthreshold electrical properties and excitability in skeletal muscle.

scientific article

Arrhythmic substrate, slowed propagation and increased dispersion in conduction direction in the right ventricular outflow tract of murine Scn5a+/- hearts.

scientific article

Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart.

scientific article published on January 2007

Atrial arrhythmia, triggering events and conduction abnormalities in isolated murine RyR2-P2328S hearts

scientific article published on 4 October 2012

Calcium-dependent Nedd4-2 upregulation mediates degradation of the cardiac sodium channel Nav1.5: implications for heart failure

scientific article

Conduction slowing contributes to spontaneous ventricular arrhythmias in intrinsically active murine RyR2-P2328S hearts

scientific article published on 06 November 2012

Control of cell volume in skeletal muscle.

scientific article published on 19 December 2008

Determinants of myocardial conduction velocity: implications for arrhythmogenesis

scientific article published on June 28, 2013

Detubulation abolishes membrane potential stabilization in amphibian skeletal muscle

scientific article

Detubulation experiments localise delayed rectifier currents to the surface membrane of amphibian skeletal muscle fibres.

scientific article published in January 2004

Dimethyl sulphoxide addition or withdrawal causes biphasic volume changes and its withdrawal causes t‐system vacuolation in skeletal muscle

scientific article published on November 15, 2011

Effect of repetitive stimulation on cell volume and its relationship to membrane potential in amphibian skeletal muscle

scientific article published on 11 January 2006

Extracellular charge adsorption influences intracellular electrochemical homeostasis in amphibian skeletal muscle.

scientific article

Extracellular magnesium and calcium reduce myotonia in ClC-1 inhibited rat muscle

scientific article

Flecainide exerts paradoxical effects on sodium currents and atrial arrhythmia in murine RyR2-P2328S hearts.

scientific article published on 23 April 2015

Functional consequences of NKCC2 splice isoforms: insights from a Xenopus oocyte model

scientific article published on 29 January 2014

Ion channel gating in cardiac ryanodine receptors from the arrhythmic RyR2-P2328S mouse

scientific article published on 21 May 2019

Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation

scientific article published on 30 May 2013

Measurement and interpretation of electrocardiographic QT intervals in murine hearts

scientific article

Membrane potential stabilization in amphibian skeletal muscle fibres in hypertonic solutions.

scientific article

Membrane potentials in Rana temporaria muscle fibres in strongly hypertonic solutions

scientific article published on 19 October 2006

Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.

scientific article

Pro-arrhythmic atrial phenotypes in incrementally paced murine Pgc1β-/- hearts: effects of age.

scientific article published on 27 September 2017

Quantitative techniques for steady-state calculation and dynamic integrated modelling of membrane potential and intracellular ion concentrations.

scientific article published on 2 November 2006

Reciprocal dihydropyridine and ryanodine receptor interactions in skeletal muscle activation

scientific article published on 13 October 2011

Relationships between resting conductances, excitability, and t-system ionic homeostasis in skeletal muscle.

scientific article published on 13 June 2011

Separation of detubulation and vacuolation phenomena in amphibian skeletal muscle

scientific article published on 01 January 2002

The RyR2-P2328S mutation downregulates Nav1.5 producing arrhythmic substrate in murine ventricles.

scientific article published on 6 November 2015

The complexity of clinically-normal sinus-rhythm ECGs is decreased in equine athletes with a diagnosis of paroxysmal atrial fibrillation

scientific article published on 22 April 2020

The contribution of refractoriness to arrhythmic substrate in hypokalemic Langendorff-perfused murine hearts.

scientific article published on 13 February 2007

The determinants of transverse tubular volume in resting skeletal muscle.

scientific article

The effect of extracellular tonicity on the anatomy of triad complexes in amphibian skeletal muscle.

scientific article published in January 2003

The influence of intracellular lactate and H+ on cell volume in amphibian skeletal muscle

scientific article published on 13 April 2006

The tubular vacuolation process in amphibian skeletal muscle

scientific article

Translational imaging studies of cortical spreading depression in experimental models for migraine aura.

scientific article