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List of works by Thomas Fath

A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau.

scientific article published on 22 June 2007

A Novel Microfluidic Device-Based Neurite Outgrowth Inhibition Assay Reveals the Neurite Outgrowth-Promoting Activity of Tropomyosin Tpm3.1 in Hippocampal Neurons

scientific article published on 14 September 2018

A role for tropomyosins in activity-dependent bulk endocytosis?

scientific article published on 22 May 2017

A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

scientific article published in Nature Communications

Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function.

scientific article

Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation

scientific article published on 5 August 2009

Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons.

scientific article published on 20 October 2015

Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders.

scientific article

Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice

scientific article

Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton

scientific article published on 15 May 2015

Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice

scientific article published on 27 September 2019

Developmental Profiling of Tropomyosin Expression in Mouse Brain Reveals Tpm4.2 as the Major Post-synaptic Tropomyosin in the Mature Brain

scientific article published on 22 December 2017

Divergent regulation of the sarcomere and the cytoskeleton.

scientific article published on 18 October 2007

Expression Pattern of the Aspartyl-tRNA Synthetase DARS in the Human Brain.

scientific article published on 20 March 2018

Functional characterisation of filamentous actin probe expression in neuronal cells

scientific article published on 16 November 2017

Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response

scientific article published on 06 March 2008

Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability.

scientific article

Hypoxic postconditioning enhances functional recovery following endothelin-1 induced middle cerebral artery occlusion in conscious rats

scientific article published on 17 May 2018

In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL.

scientific article published on 2 November 2016

Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease

scientific article published on 4 April 2016

New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2.

scientific article published on 12 March 2010

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

scholarly article

Peptide Nanofiber Substrates for Long-Term Culturing of Primary Neurons

article

Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein

scientific article

Primary support cultures of hippocampal and substantia nigra neurons

article

Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

scientific article

Regulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in Disease

scientific article

Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66.

scientific article published on 29 January 2016

Special issue on 'Cytoskeleton-dependent regulation of neuronal network formation'.

scientific article published in October 2017

Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes

scientific article published on 19 November 2019

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease

scientific article published on 22 October 2019

Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.

scientific article published in October 2000

TPM3 and TPM4 gene products segregate to the postsynaptic region of central nervous system synapses.

scientific article published on November 2011

Tau exacerbates excitotoxic brain damage in an animal model of stroke

scientific article published on 7 September 2017

The Only Constant Is Change: Next Generation Materials and Medical Device Design for Physical and Mental Health

scientific article published on 9 June 2016

Tropomodulin isoforms utilize specific binding functions to modulate dendrite development

scientific article published on 29 April 2016

Tropomodulin's Actin-Binding Abilities Are Required to Modulate Dendrite Development

scientific article published on 09 October 2018

Tropomodulins and tropomyosins - organizers of cellular microcompartments.

scientific article

Tropomodulins are negative regulators of neurite outgrowth.

scientific article

Tropomyosin isoforms have specific effects on the transcriptome of undifferentiated and differentiated B35 neuroblastoma cells.

scientific article

Tropomyosins in the healthy and diseased nervous system.

scientific article published on 10 June 2016

Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells.

scientific article published on 6 November 2013

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