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List of works by Maria Pia Rigobello

A possible transport mechanism for aluminum in biological membranes.

scientific article

Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands

scientific article

Antioxidant Properties of Fermented Soy during Shelf Life

scientific article published on 01 September 2019

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

scientific article

Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches

scientific article published on 2 November 2017

Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines.

scientific article published on 22 June 2010

Differential effect of calcium ions on the cytosolic and mitochondrial thioredoxin reductase

scientific article published on 20 March 2006

Dimers of glutaredoxin 2 as mitochondrial redox sensors in selenite-induced oxidative stress

scientific article published on 01 July 2019

Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase

scientific article

Effects of nitrosopropofol on mitochondrial energy-converting system

scientific article published in October 2002

Effects of redox modulation by inhibition of thioredoxin reductase on radiosensitivity and gene expression.

scientific article published on July 2012

Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds

scientific article published on 4 October 2008

Enzymatic oxidation of ansa-ferrocifen leads to strong and selective thioredoxin reductase inhibition in vitro.

scientific article published on 5 August 2016

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

Evaluation of the antioxidant properties of propofol and its nitrosoderivative. comparison with homologue substituted phenols

scientific article

Exploring the C^N^C theme: Synthesis and biological properties of tridentate cyclometalated gold(III) complexes

scientific article published on 9 August 2017

Fluorescent silver(I) and gold(I)-N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights

scientific article published on August 2013

Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions

scientific article published in October 2004

Gold(I) NHC-based homo- and heterobimetallic complexes: synthesis, characterization and evaluation as potential anticancer agents

scientific article published on 23 July 2015

Gold(I) carbene complexes causing thioredoxin 1 and thioredoxin 2 oxidation as potential anticancer agents

scientific article published on 4 June 2012

Gold(I) complexes determine apoptosis with limited oxidative stress in Jurkat T cells

scientific article

Gold(III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway.

scientific article published on October 2007

Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones

scientific article

Identification of New Peptides from Fermented Milk Showing Antioxidant Properties: Mechanism of Action

scientific article published on 29 January 2020

In vitro antitumour activity of water soluble Cu(I), Ag(I) and Au(I) complexes supported by hydrophilic alkyl phosphine ligands.

scientific article published on 5 November 2010

Induction of mitochondrial permeability transition by auranofin, a gold(I)-phosphine derivative

scientific article published on August 2002

Inhibition of lipid peroxidation by S-nitrosoglutathione and copper

scientific article

Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.

scientific article published on 22 December 2006

Inhibition of thioredoxin reductase by lanthanum chloride ⬇️

scientific article published on August 31, 2012

Insight into antioxidant properties of milk-derived bioactive peptides in vitro and in a cellular model

scientific article published on 12 March 2019

Insights into the strong in-vitro anticancer effects for bis(triphenylphosphane)iminium compounds having perchlorate, tetrafluoridoborate and bis(chlorido)argentate anions

scientific article published on 5 September 2015

Interaction of selenite and tellurite with thiol-dependent redox enzymes: Kinetics and mitochondrial implications.

scientific article published on 11 March 2011

Methylselenol formed by spontaneous methylation of selenide is a superior selenium substrate to the thioredoxin and glutaredoxin systems

scientific article published in 2012

Milk-derived bioactive peptides protect against oxidative stress in a Caco-2 cell model.

scientific article published in February 2018

Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State.

scientific article published on 15 March 2016

Mitochondrial thioredoxin reductase and thiol status

scientific article published in January 2002

Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c.

scientific article published in February 2004

Mitochondrial thioredoxin reductase purification, inhibitor studies, and role in cell signaling

scientific article published on 20 June 2010

Osmocenyl-tamoxifen derivatives target the thioredoxin system leading to a redox imbalance in Jurkat cells.

scientific article published on 13 April 2016

Oxidative changes in lipids, proteins, and antioxidants in yogurt during the shelf life

scientific article published on 25 July 2017

Platinum(II) complexes bearing triphenylphosphine and chelating oximes: antiproliferative effect and biological profile in resistant cells

scientific article published on 03 June 2020

Principles in Redox Signaling: From Chemistry to Functional Significance ⬇️

scientific article published on February 19, 2013

Significance of the mitochondrial thioredoxin reductase in cancer cells: An update on role, targets and inhibitors

scientific article

Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects

scientific article published on 24 September 2019

Synthesis and characterization of azolate gold(I) phosphane complexes as thioredoxin reductase inhibiting antitumor agents

scientific article

Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells.

scientific article

Thallium induces apoptosis in Jurkat cells.

scientific article

The determining role of mitochondrial ROS generation and monoamine oxidase activity in doxorubicin-induced cardiotoxicity

scientific article published on 11 June 2020

The modulation of thiol redox state affects the production and metabolism of hydrogen peroxide by heart mitochondria

scientific article published in September 2005

Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes

scientific article published on April 2010

Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(iii) compounds studied with combined mass spectrometry and biochemical assays

Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift

scientific article published on 29 May 2009

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