Search filters

List of works by Aart J van der Lely

A multivariable prediction model for pegvisomant dosing: monotherapy and in combination with long-acting somatostatin analogues.

scientific article

Addisonian crisis and relative adrenal failure

scientific article (publication date: May 2003)

Adrenal function in adult long-term survivors of nephroblastoma and neuroblastoma ⬇️

scientific article published on April 16, 2012

An Age-Dependent Interaction with Leptin Unmasks Ghrelin's Bone-Protective Effects ⬇️

scientific article published on June 14, 2012

Bridging the gap: metabolic and endocrine care of patients during transition

scientific article

Carcinoid syndrome: diagnosis and medical management

scientific article

Clinical review 166: Growth hormone receptor antagonists

scientific article published on April 2004

Coadministration of lanreotide Autogel and pegvisomant normalizes IGF1 levels and is well tolerated in patients with acromegaly partially controlled by somatostatin analogs alone

scientific article

Combination treatment with somatostatin analogues and pegvisomant in acromegaly

scientific article

Combined treatment of somatostatin analogues with pegvisomant in acromegaly

scientific article

Cortistatin rather than somatostatin as a potential endogenous ligand for somatostatin receptors in the human immune system

scientific article

Des-Acyl Ghrelin: A Metabolically Active Peptide ⬇️

scientific article published on April 25, 2013

Development of ACRODAT®, a new software medical device to assess disease activity in patients with acromegaly.

scientific article published on 8 September 2017

Diagnostic imaging of dopamine receptors in pituitary adenomas

scientific article published on April 2007

Diagnostic value of a ghrelin test for the diagnosis of GH deficiency after subarachnoid hemorrhage

scientific article published on 14 September 2013

Efficacy and Safety of Switching to Pasireotide in Patients With Acromegaly Controlled With Pegvisomant and First-Generation Somatostatin Analogues (PAPE Study).

scientific article published on 15 November 2017

Efficacy and Safety of switching to Pasireotide in Acromegaly Patients controlled with Pegvisomant and Somatostatin Analogues: PAPE extension study

scientific article published on 12 October 2018

Endocrine activities of cortistatin-14 and its interaction with GHRH and ghrelin in humans

scientific article

Endocrine sequelae and metabolic syndrome in adult long-term survivors of childhood acute myeloid leukemia

scientific article published on 9 January 2013

Expert consensus document: A consensus on the medical treatment of acromegaly

scientific article

Expression of somatostatin, cortistatin, and somatostatin receptors in human monocytes, macrophages, and dendritic cells

scientific article

Extra-hepatic Acromegaly

scientific article published on 15 March 2013

Genetic manipulation of the ghrelin signaling system in male mice reveals bone compartment specificity of acylated and unacylated ghrelin in the regulation of bone remodeling

scientific article published on 25 July 2014

Ghrelin and bone.

scientific article published on January 2008

Ghrelin and new metabolic frontiers

scientific article published on 21 January 2009

Ghrelin and the endocrine pancreas.

scientific article published on October 2003

Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes

scientific article

How to Position Pasireotide LAR Treatment in Acromegaly

scientific article published on 01 June 2019

In Vitro Head-to-Head Comparison Between Octreotide and Pasireotide in GH-Secreting Pituitary Adenomas.

scientific article published on 13 March 2017

In active acromegaly, IGF1 bioactivity is related to soluble Klotho levels and quality of life

scientific article published on 15 April 2014

Insights from growth hormone receptor blockade.

scientific article

Lanreotide Autogel 120 mg at extended dosing intervals in patients with acromegaly biochemically controlled with octreotide LAR: the LEAD study

scientific article

Long-acting somatostatin analog therapy of acromegaly: a meta-analysis

scientific article

Long-term efficacy and safety of pegvisomant in combination with long-acting somatostatin analogs in acromegaly

scientific article published on 17 June 2014

Mechanisms in endocrinology: Ghrelin: the differences between acyl- and des-acyl ghrelin

scientific article published on 16 August 2012

Medical approach to pituitary tumors

scientific article published on January 2014

Medical therapy of acromegaly: efficacy and safety of somatostatin analogues

scientific article

Modulation of Glucocorticoid Metabolism by the GH-IGF-I Axis ⬇️

scientific article published on December 16, 2010

Obesity Is Underestimated Using Body Mass Index and Waist-Hip Ratio in Long-Term Adult Survivors of Childhood Cancer ⬇️

scientific article published on August 14, 2012

Octreoscan Radioreceptor Imaging ⬇️

scientific article published on April 1, 2003

Pasireotide responsiveness in acromegaly is mainly driven by somatostatin receptor subtype 2 expression

scientific article published on 01 March 2019

Pasireotide, a multi-somatostatin receptor ligand with potential efficacy for treatment of pituitary and neuroendocrine tumors

scientific article published on February 1, 2013

Pegvisomant Treatment in Acromegaly

scientific article

Pegvisomant and not somatostatin receptor ligands (SRLs) is first line medical therapy for acromegaly

scientific article published on 01 April 2020

Pegvisomant for acromegaly: does it always works?

scientific article published on 22 August 2019

Pegvisomant in combination with long-acting somatostatin analogues in acromegaly: the role of the GH receptor deletion of exon 3.

scientific article published on 4 August 2015

Pharmacological therapy for acromegaly: a critical review

scientific article published in January 2004

Pheochromocytomas and pituitary adenomas in three patients with MAX exon deletions

scientific article published on 13 March 2018

Pituitary dysfunction after aneurysmal subarachnoid haemorrhage: course and clinical predictors—the HIPS study

scientific article published on 6 November 2014

Pregnancy and acromegaly.

scientific article

Review of current and emerging treatment options in acromegaly

scientific article

Risk factors for subsequent endocrine-related cancer in childhood cancer survivors

scientific article

Should we consider des-acyl ghrelin as a separate hormone and if so, what does it do?

scientific article published on 07 April 2014

Soluble Klotho: a possible predictor of quality of life in acromegaly patients

scientific article published on 24 April 2020

Somatostatin Receptor Expression in GH-Secreting Pituitary Adenomas Treated with Long-Acting Somatostatin Analogues in Combination with Pegvisomant.

scientific article published on 25 July 2016

Somatostatin analog and pegvisomant combination therapy for acromegaly

scientific article published on October 2009

Somatostatin receptor imaging for neuroendocrine tumors

scientific article published on January 2006

T2-signal intensity, SSTR expression, and somatostatin analogs efficacy predict response to pasireotide in acromegaly

scientific article published on 01 June 2020

The Effect of the Exon-3-Deleted Growth Hormone Receptor on Pegvisomant-Treated Acromegaly: A Systematic Review and Meta-Analysis.

scientific article

The acylated/unacylated ghrelin ratio is similar in acromegaly patients during different treatment regimens

scientific article published on 11 April 2017

The medical treatment of acromegaly

scientific article published on July 2007

The position of combined medical treatment in acromegaly

scientific article published on 01 November 2019

The potential role of biomarkers in predicting gestational diabetes

scientific article

The role of AIP variants in pituitary adenomas and concomitant thyroid carcinomas in the Netherlands: a nationwide pathology registry (PALGA) study

scientific article published on 24 April 2020

Unacylated ghrelin and obestatin increase islet cell mass and prevent diabetes in streptozotocin-treated newborn rats.

scientific article published on 09 April 2010

Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor.

scientific article

Unacylated ghrelin modulates circulating angiogenic cell number in insulin-resistant states

scientific article

Unacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice

scientific article

Unacylated ghrelin suppresses ghrelin-induced neuronal activity in the hypothalamus and brainstem of male rats [corrected].

scientific article

Very long-term sequelae of craniopharyngioma.

scientific article

What is active acromegaly and which parameters do we have? ⬇️

scientific article published on May 1, 2012

What is the efficacy of switching to weekly pegvisomant in acromegaly patients well controlled on combination therapy?

scientific article published on 22 February 2016

Paulina is supported by:

About Paulina

Help