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List of works by Daniel J Murphy

A Neuronal Relay Mediates a Nutrient Responsive Gut/Fat Body Axis Regulating Energy Homeostasis in Adult Drosophila

scientific article published on 18 October 2018

An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma.

scientific article published on 23 May 2016

Author Correction: CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity.

scientific article published on 13 April 2018

BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues

scientific article

BIM's up first

scientific article published on December 2014

CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity

scientific article published on 4 December 2017

Calcium signalling links MYC to NUAK1.

scientific article published on 6 November 2017

Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress

scientific article published on 2 March 2018

Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

scientific article

Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo

scientific article

Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics

scientific article published on 13 December 2016

Distinct thresholds govern Myc's biological output in vivo

scientific article

Evidence of cancer-promoting roles for AMPK and related kinases

scientific article

Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism

scientific article published on 01 October 2019

Human SWI-SNF component BRG1 represses transcription of the c-fos gene

scientific article

IKKβ Kinase Promotes Stemness, Migration, and Invasion in KRAS-Driven Lung Adenocarcinoma Cells

scientific article published on 13 August 2020

Id2 is dispensable for Myc-induced epidermal neoplasia.

scientific article

Identification of a Clinically Relevant Signature for Early Progression in KRAS-Driven Lung Adenocarcinoma.

scientific article published on 29 April 2019

In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells.

scientific article

Inhibition of cyclin D1 gene transcription by Brg-1.

scientific article published on 12 December 2007

Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells.

scientific article

Is oxidative stress MYC’s Achilles heel?

scientific article published on 01 July 2018

Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death

scientific article

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance.

scientific article

Mesothelioma: Identical Routes to Malignancy from Asbestos and Carbon Nanotubes

scientific article

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response

scientific article published in 2024

Modelling Myc inhibition as a cancer therapy

scientific article

Oncogene-dependent tumor suppression: using the dark side of the force for cancer therapy.

scientific article published on January 2005

Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation

scientific article

Predicting lung cancer recurrence from circulating tumour DNA. Commentary on 'Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution'.

scientific article published on 16 June 2017

Progress and challenges in Mesothelioma: From bench to bedside

scientific article published on 26 November 2017

Repression of the Type I Interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in Pancreatic Ductal Adenocarcinoma

scientific article published on 21 March 2020

THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer

scientific article published on 11 January 2022

The 2014 Beatson International Cancer Conference: Powering the Cancer Machine

The ERBB network facilitates KRAS-driven lung tumorigenesis

scientific article published on 01 June 2018

The Spy1/RINGO family represents a novel mechanism regulating mammary growth and tumorigenesis

scientific article published in May 2008

The pathogenesis of mesothelioma is driven by a dysregulated translatome

scientific article published on 13 August 2021