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List of works by Alexander Weng

A convenient method for saponin isolation in tumour therapy.

scientific article

A simple method for isolation of Gypsophila saponins for the combined application of targeted toxins and saponins in tumor therapy.

scientific article

Augmenting the Efficacy of Immunotoxins and Other Targeted Protein Toxins by Endosomal Escape Enhancers ⬇️

scientific article

Combinatorial approach to increase efficacy of Cetuximab, Panitumumab and Trastuzumab by dianthin conjugation and co-application of SO1861.

scientific article published on 4 August 2015

Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis.

scientific article

Dianthin-30 or gelonin versus monomethyl auristatin E, each configured with an anti-calcitonin receptor antibody, are differentially potent in vitro in high-grade glioma cell lines derived from glioblastoma

scientific article

Dianthin-EGF is an effective tumor targeted toxin in combination with saponins in a xenograft model for colon carcinoma

scientific article

Electrophoretic isolation of saponin fractions from Saponinum album and their evaluation in synergistically enhancing the receptor-specific cytotoxicity of targeted toxins.

scientific article published on 14 October 2011

Electrophoretic mobility as a tool to separate immune adjuvant saponins from Quillaja saponaria Molina

scientific article

Enhancement of cytotoxicity of ribosome-inactivating-protein type I by saponinum album is not based on stimulation of phagocytosis.

scientific article published in July 2008

Enhancement of toxicity of saporin-based toxins by Gypsophila saponins--kinetic of the saponin.

scientific article

Epidermal growth factor receptor expression affects the efficacy of the combined application of saponin and a targeted toxin on human cervical carcinoma cells.

scientific article

Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies.

scientific article published on 29 March 2017

High-speed countercurrent chromatographic recovery and off-line electrospray ionization mass spectrometry profiling of bisdesmodic saponins from Saponaria officinalis possessing synergistic toxicity enhancing properties on targeted antitumor toxins.

scientific article

Immunotoxins constructed with ribosome-inactivating proteins and their enhancers: a lethal cocktail with tumor specific efficacy

scientific article

Improved intracellular delivery of peptide- and lipid-nanoplexes by natural glycosides.

scientific article

Liquid-chromatographic profiling of Saponinum album (Merck)

scientific article published on October 1, 2011

Macromolecular interactions of triterpenoids and targeted toxins: role of saponins charge.

scientific article published on 22 July 2013

MicroRNAs as New Bioactive Components in Medicinal Plants

scientific article

Modified trastuzumab and cetuximab mediate efficient toxin delivery while retaining antibody-dependent cell-mediated cytotoxicity in target cells

scientific article published on 7 October 2013

Real time monitoring of the cell viability during treatment with tumor-targeted toxins and saponins using impedance measurement.

scientific article

Reporter assay for endo/lysosomal escape of toxin-based therapeutics

scientific article

Ribosome-inactivating and related proteins.

scientific article published on 08 May 2015

Saponins from Saponaria officinalis L. Augment the Efficacy of a Rituximab-Immunotoxin.

scientific article published on 8 July 2016

Saponins modulate the intracellular trafficking of protein toxins

scientific article

Small structural differences of targeted anti-tumor toxins result in strong variation of protein expression.

scientific article

Soapwort saponins trigger clathrin-mediated endocytosis of saporin, a type I ribosome-inactivating protein

scientific article published on 15 August 2008

Targeted dianthin is a powerful toxin to treat pancreatic carcinoma when applied in combination with the glycosylated triterpene SO1861.

scientific article published on 29 July 2017

Targeted tumor therapy by epidermal growth factor appended toxin and purified saponin: an evaluation of toxicity and therapeutic potential in syngeneic tumor bearing mice.

scientific article

The distribution of saponins in vivo affects their synergy with chimeric toxins against tumours expressing human epidermal growth factor receptors in mice.

scientific article

The endocytic uptake pathways of targeted toxins are influenced by synergistically acting Gypsophila saponins.

scientific article published on 26 October 2011

The toxin component of targeted anti-tumor toxins determines their efficacy increase by saponins.

scientific article published on 24 January 2012

Triterpenoid saponin augmention of saporin-based immunotoxin cytotoxicity for human leukaemia and lymphoma cells is partially immunospecific and target molecule dependent

scientific article published on 27 October 2014

Triterpenoid saponins from the roots of Gypsophila trichotoma Wender.

scientific article published on 3 April 2013

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