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Authors whose works are in public domain in at least one jurisdiction

List of works by Richard G. Doveston

1-15 of 15 results

A divergent synthetic approach to diverse molecular scaffolds: assessment of lead-likeness using LLAMA, an open-access computational tool

scientific article

Modulators of 14-3-3 Protein-Protein Interactions

scientific article

Stabilization of protein-protein interactions in drug discovery

scientific article published on 11 July 2017

A systematic approach to diverse, lead-like scaffolds from α,α-disubstituted amino acids

scientific article published in June 2015

Towards the realisation of lead-oriented synthesis

scientific article published on November 15, 2013

Structural interface between LRRK2 and 14-3-3 protein.

scientific article published on 15 February 2017

Synthesis and Demonstration of the Biological Relevance of sp3 -rich Scaffolds Distantly Related to Natural Product Frameworks.

scientific article published on 6 October 2017

A unified lead-oriented synthesis of over fifty molecular scaffolds

scientific article

Total synthesis of an oxepine natural product, (±)-janoxepin

scientific article published on 30 January 2012

Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.

scientific article published on 22 June 2017

Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt

scientific article published on 3 February 2021

Elucidation of an Allosteric Mode of Action for a Thienopyrazole RORγt Inverse Agonist

scientific article published on 12 March 2020

Characterising the Protein-Protein Interaction Between MDM2 and 14-3-3σ; Proof of Concept for Small Molecule Stabilisation

Regulation of p53 by the 14-3-3 protein interaction network: new opportunities for drug discovery in cancer

Cooperative stabilisation of 14-3-3σ protein-protein interactions covalent protein modification