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List of works by Rajasekharan Somasundaram

A slow-cycling subpopulation of melanoma cells with highly invasive properties.

scientific article published on 18 September 2017

A stress-induced early innate response causes multidrug tolerance in melanoma

scientific article published on 24 November 2014

Animal models of human-derived cancer vaccines.

scientific article published on August 1995

Anti-idiotype cancer vaccines: pre-clinical and clinical studies

scientific article published on 01 November 1991

Anti-idiotype vaccine in colorectal cancer patients

scientific article published on 01 October 1993

Anti-idiotypic antibody (ab2) vaccines: coupling of Ab2 BR3E4 to KLH increases humoral and/or cellular immune responses in animals and colorectal cancer patients

scientific article published on 01 October 2001

Antibody dependent cellular cytotoxicity and complement mediated cytotoxicity on leukemic cells mediated by anti K562 monoclonal antibodies

scientific article published on 01 February 1990

Antimelanoma CTL recognizes peptides derived from an ORF transcribed from the antisense strand of the 3' untranslated region of TRIT1.

scientific article published on 14 January 2015

CD4(+), HLA class I-restricted, cytolytic T-lymphocyte clone against primary malignant melanoma cells

scientific article published on 01 January 2000

CD8+, HLA-unrestricted, cytotoxic T-lymphocyte line against malignant melanoma.

scientific article

CXC chemokine ligand 12 (stromal cell-derived factor 1 alpha) and CXCR4-dependent migration of CTLs toward melanoma cells in organotypic culture

scientific article

Cancer vaccines: single-epitope anti-idiotype vaccine versus multiple-epitope antigen vaccine

scientific article published in June 2000

Chemokines and the microenvironment in neuroectodermal tumor-host interaction

scientific article

Cloned antigens and antiidiotypes

scientific article published on 01 April 1995

Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma

scientific article published on 12 April 2018

Colon cancer antigen and anti-idiotype vaccines.

scientific article published on January 2003

Colon carcinoma cells induce CXCL11-dependent migration of CXCR3-expressing cytotoxic T lymphocytes in organotypic culture.

scientific article published on 17 June 2006

Combination therapy of immunocytokines with ipilimumab: a cure for melanoma?

Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target

scientific article published on 13 September 2013

Concanavalin A induced suppressor cell activity and autorosette forming cells in chronic myeloid leukemia patients ⬇️

scientific article published on December 1, 1983

Cytotoxic T-cell clone against rectal carcinoma induced by stimulation of a patient's peripheral blood mononuclear cells with autologous cultured tumor cells

scientific article published on 01 May 1997

Detection of HLA class II-dependent T helper antigen using antigen phage display.

scientific article

Effect of BM 12 531 on in vitro induction of suppressor cells by concanavalin A in cancer patients and normal healthy donors

scientific article published on 01 January 1986

Erratum: A stress-induced early innate response causes multidrug tolerance in melanoma

article

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

scientific article published in Nature

Functional & phenotypic studies on leukaemic T cells from acute lymphoblastic leukaemia

scientific article published on 01 December 1988

Heterogeneity in Melanoma

scientific article

Human colorectal cancer (CRC) antigen CO17-1A/GA733 encoded by adenovirus inhibits growth of established CRC cells in mice.

scientific article published in July 1997

Human leukocyte antigen-A2-restricted CTL responses to mutated BRAF peptides in melanoma patients.

scientific article published on March 2006

Immunogenicity of recombinant GA733-2E antigen (CO17-1A, EGP, KS1-4, KSA, Ep-CAM) in gastro-intestinal carcinoma patients

scientific article published on 01 April 2001

Immunomodulatory activity of monoclonal anti-idiotypic antibody to anti-colorectal carcinoma antibody CO17-1A in animals and patients

scientific article published on 01 May 1994

Immunotargeting of tumor subpopulations in melanoma patients: A paradigm shift in therapy approaches

scientific article published on November 2012

In vitro generation of effector cells cytotoxic to autologous targets from chronic myeloid leukemia patients in remission

scientific article published on 01 January 1988

In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2.

scientific article

Indomethacin to the rescue of TRAIL-resistant melanomas

scientific article published on 01 May 2014

Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma

scientific article published on 21 March 2018

Induction of antigen-specific T and B cell immunity in colon carcinoma patients by anti-idiotypic antibody

scientific article published on 01 September 1995

Induction of cellular immunity by anti-idiotypic antibodies mimicking GD2 ganglioside

scientific article published on 11 February 2003

Interleukin-2 mediated regulation of mitogen-activated T cell reactivity from different lymphoid sources in patients with squamous cell carcinoma of the oral cavity

scientific article published on 01 July 1989

Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations

scientific article published on January 2012

Isolation of melanoma cell subpopulations using negative selection

scientific article published on January 2014

Isolation of the melanoma-associated antigen p23 using antibody phage display.

scientific article

Limitations of the severe combined immunodeficiency (SCID) mouse model for study of human B-cell responses

scientific article published on 01 April 1995

Meeting report from the 10th International Congress of the Society for Melanoma Research, Philadelphia, PA, November 2013.

scientific article published on 6 May 2014

Melanoma exosomes: messengers of metastasis.

scientific article

Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature

scientific article published on July 2012

Migration of cytotoxic T lymphocytes toward melanoma cells in three-dimensional organotypic culture is dependent on CCL2 and CCR4

scientific article published on 01 February 2006

Monoclonal anti-idiotypic antibody functionally mimics the human gastrointestinal carcinoma epitope GA733

scientific article published on 01 February 1996

Monoclonal anti-idiotypic antibody mimicking the gastrointestinal carcinoma-associated epitope CO17-1A elicits antigen-specific humoral and cellular immune responses in colorectal cancer patients

scientific article published on 01 April 2003

Monocyte/macrophage functions in patients with squamous cell carcinoma of the oral cavity

scientific article published on 01 December 1989

Nivolumab in combination with ipilimumab for the treatment of melanoma

scientific article published on October 2015

Nucleophosmin is recognized by a cytotoxic T cell line derived from a rectal carcinoma patient.

scientific article

Peptides mimicking GD2 ganglioside elicit cellular, humoral and tumor-protective immune responses in mice

scientific article

Preferential involvement of CX chemokine receptor 4 and CX chemokine ligand 12 in T-cell migration toward melanoma cells.

scientific article published on 4 October 2006

Propagation of cytotoxic effectors from chronic myeloid leukemia patients and cloning of cytotoxic T cells

scientific article published on 01 January 1988

RETRACTED ARTICLE: IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance

retracted scholarly article

Recombinant CD63/ME491/neuroglandular/NKI/C-3 antigen inhibits growth of established tumors in transgenic mice

scientific article published on 01 September 2003

Relapse of melanoma after successful adoptive T-cell therapy: escape through inflammation-induced phenotypic melanoma cell plasticity

scientific article published in January 2013

SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway.

scientific article published on 24 October 2013

Serum antibodies to EpCAM in healthy donors but not ulcerative colitis patients

scientific article published on 21 July 2005

Shared MHC class II-dependent melanoma ribosomal protein L8 identified by phage display

article

Targeting CD20 in melanoma patients at high risk of disease recurrence.

scientific article

The Multifaceted Roles of B Cells in Solid Tumors: Emerging Treatment Opportunities

scientific article published on 9 March 2017

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

scientific article published on 19 September 2017

Type I-polarized BRAF-pulsed dendritic cells induce antigen-specific CD8+ T cells that impact BRAF-mutant murine melanoma

scientific article published on 8 October 2015

Will engineered T cells expressing CD20 scFv eradicate Melanoma?

scientific article published on April 2011

[1st successful immunization of pancreas and colorectal carcinoma patients with CO17-1A-vaccine]

scientific article published on 01 January 1998

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